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Deep Learning (DL) methods can reconstruct highly accelerated magnetic resonance imaging (MRI) scans, but they rely on application-specific large training datasets and often generalize poorly to out-of-distribution data. Self-supervised…

Image and Video Processing · Electrical Eng. & Systems 2026-04-24 Hongze Yu , Jeffrey A. Fessler , Yun Jiang

Deformable image registration is a fundamental task in medical image analysis and plays a crucial role in a wide range of clinical applications. Recently, deep learning-based approaches have been widely studied for deformable medical image…

Image and Video Processing · Electrical Eng. & Systems 2023-07-03 Jing Zou , Noémie Debroux , Lihao Liu , Jing Qin , Carola-Bibiane Schönlieb , Angelica I Aviles-Rivero

Supervised Deep-Learning (DL)-based reconstruction algorithms have shown state-of-the-art results for highly-undersampled dynamic Magnetic Resonance Imaging (MRI) reconstruction. However, the requirement of excessive high-quality…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Jie Feng , Ruimin Feng , Qing Wu , Zhiyong Zhang , Yuyao Zhang , Hongjiang Wei

Nonlinear image registration continues to be a fundamentally important tool in medical image analysis. Diagnostic tasks, image-guided surgery and radiotherapy as well as motion analysis all rely heavily on accurate intra-patient alignment.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Mattias P. Heinrich

Deep learning based deformable registration methods have become popular in recent years. However, their ability to generalize beyond training data distribution can be poor, significantly hindering their usability. LUMIR brain registration…

Computer Vision and Pattern Recognition · Computer Science 2025-10-28 Joel Honkamaa , Pekka Marttinen

We present KeyMorph, a deep learning-based image registration framework that relies on automatically detecting corresponding keypoints. State-of-the-art deep learning methods for registration often are not robust to large misalignments, are…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Alan Q. Wang , Evan M. Yu , Adrian V. Dalca , Mert R. Sabuncu

Recent denoising algorithms based on the "blind-spot" strategy show impressive blind image denoising performances, without utilizing any external dataset. While the methods excel in recovering highly contaminated images, we observe that…

Image and Video Processing · Electrical Eng. & Systems 2022-04-07 Chaewon Kim , Jaeho Lee , Jinwoo Shin

Deformable image registration (DIR) remains a fundamental yet challenging problem in medical image analysis, largely due to the prohibitively high-dimensional deformation space of dense displacement fields and the scarcity of voxel-level…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Runxun Zhang , Yizhou Liu , Li Dongrui , Bo XU , Jingwei Wei

Deformable image registration is inherently a multi-objective optimization (MOO) problem, requiring a delicate balance between image similarity and deformation regularity. These conflicting objectives often lead to poor optimization…

Computer Vision and Pattern Recognition · Computer Science 2024-10-24 Yi Zhang , Yidong Zhao , Qian Tao

Deformable image registration (DIR) is a cornerstone of medical image analysis, enabling spatial alignment for tasks like comparative studies and multi-modal fusion. While learning-based methods (e.g., CNNs, transformers) offer fast…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Nikita Drozdov , Marat Zinovev , Dmitry Sorokin

Medical image registration is a fundamental and vital task which will affect the efficacy of many downstream clinical tasks. Deep learning (DL)-based deformable image registration (DIR) methods have been investigated, showing…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Ti Bai , Muhan Lin , Xiao Liang , Biling Wang , Michael Dohopolski , Bin Cai , Dan Nguyen , Steve Jiang

State-of-the-art, high capacity deep neural networks not only require large amounts of labelled training data, they are also highly susceptible to label errors in this data, typically resulting in large efforts and costs and therefore…

Machine Learning · Computer Science 2020-07-20 Christian Haase-Schütz , Rainer Stal , Heinz Hertlein , Bernhard Sick

This paper presents DeepFLASH, a novel network with efficient training and inference for learning-based medical image registration. In contrast to existing approaches that learn spatial transformations from training data in the high…

Image and Video Processing · Electrical Eng. & Systems 2020-04-07 Jian Wang , Miaomiao Zhang

Image registration is a crucial task in signal processing, but it often encounters issues with stability and efficiency. Non-learning registration approaches rely on optimizing similarity metrics between fixed and moving images, which can…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Zihao Wang , Hervé Delingette

Data-driven deep learning approaches to image registration can be less accurate than conventional iterative approaches, especially when training data is limited. To address this whilst retaining the fast inference speed of deep learning, we…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Xi Jia , Alexander Thorley , Wei Chen , Huaqi Qiu , Linlin Shen , Iain B Styles , Hyung Jin Chang , Ales Leonardis , Antonio de Marvao , Declan P. O'Regan , Daniel Rueckert , Jinming Duan

Learning-based single image super-resolution (SISR) methods are continuously showing superior effectiveness and efficiency over traditional model-based methods, largely due to the end-to-end training. However, different from model-based…

Image and Video Processing · Electrical Eng. & Systems 2020-03-24 Kai Zhang , Luc Van Gool , Radu Timofte

Implicit neural representations (INRs) have emerged as a powerful paradigm for medical imaging via physics-informed unsupervised learning. Classical INRs optimize an entire network from scratch for each subject, leading to inefficient…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Qing Wu , Xuanyu Tian , Chenhe Du , Haonan Zhang , Xiao Wang , Le Lu , Yuyao Zhang

Deformable image registration (DIR) involves optimization of multiple conflicting objectives, however, not many existing DIR algorithms are multi-objective (MO). Further, while there has been progress in the design of deep learning…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Monika Grewal , Henrike Westerveld , Peter A. N. Bosman , Tanja Alderliesten

In the presence of large sets of labeled data, Deep Learning (DL) has accomplished extraordinary triumphs in the avenue of computer vision, particularly in object classification and recognition tasks. However, DL cannot always perform well…

Computer Vision and Pattern Recognition · Computer Science 2019-01-03 Mohammad Mahfujur Rahman , Clinton Fookes , Mahsa Baktashmotlagh , Sridha Sridharan

Image registration aims to establish spatial correspondence across pairs, or groups of images, and is a cornerstone of medical image computing and computer-assisted-interventions. Currently, most deep learning-based registration methods…

Image and Video Processing · Electrical Eng. & Systems 2021-07-12 Xiang Chen , Nishant Ravikumar , Yan Xia , Alejandro F Frangi