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Digital breast tomosynthesis (DBT) is an emerging modality for breast imaging. A typical tomosynthesis image is reconstructed from projection data acquired at a limited number of views over a limited angular range. In general, the…

Medical Physics · Physics 2009-08-19 I. Reiser , J. Bian , R. M. Nishikawa , E. Y. Sidky , X. Pan

Purpose: This work aims to develop an image reconstruction algorithm for wide-angle digital breast tomosynthesis (DBT) that has improved depth resolution and in-plane contrast while reducing non-uniformity artifacts. Approach: The image…

Optimization and Control · Mathematics 2026-05-29 Emil Y. Sidky , Adrian A. Sanchez , John Paul Phillips , Zheng Zhang , Dan Xia , Ingrid S. Reiser , Xiaochuan Pan

Digital Breast Tomosynthesis (DBT) is a widely used medical imaging modality for breast cancer screening and diagnosis, offering higher spatial resolution and greater detail through its 3D-like breast volume imaging capability. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-21 Yuexi Du , Regina J. Hooley , John Lewin , Nicha C. Dvornek

The two-dimensional nature of mammography makes estimation of the overall breast density challenging, and estimation of the true patient-specific radiation dose impossible. Digital breast tomosynthesis (DBT), a pseudo-3D technique, is now…

Digital Breast Tomosynthesis (DBT) provides an insight into the fine details of normal fibroglandular tissues and abnormal lesions by reconstructing a pseudo-3D image of the breast. In this respect, DBT overcomes a major limitation of…

Computer Vision and Pattern Recognition · Computer Science 2013-07-24 Guang Yang , John H. Hipwell , David J. Hawkes , Simon R. Arridge

Investigation of image reconstruction from data collected over a limited angular range in X-ray CT remains a topic of active research because it may yield insight into the development of imaging workflow of practical significance. This…

Medical Physics · Physics 2021-03-02 Zheng Zhang , Buxin Chen , Dan Xia , Emil Y. Sidky , Xiaochuan Pan

PURPOSE: We develop a practical, iterative algorithm for image-reconstruction in under-sampled tomographic systems, such as digital breast tomosynthesis (DBT). METHOD: The algorithm controls image regularity by minimizing the image total…

Digital Breast Tomosynthesis is an X-ray imaging technique that allows a volumetric reconstruction of the breast, from a small number of low-dose two-dimensional projections. Although it is already used in clinical setting, enhancing the…

Numerical Analysis · Mathematics 2020-07-21 Elena Morotti , Elena Loli Piccolomini

In practical applications of tomographic imaging, there are often challenges for image reconstruction due to under-sampling and insufficient data. In computed tomography (CT), for example, image reconstruction from few views would enable…

Medical Physics · Physics 2009-04-30 Emil Y. Sidky , Chien-Min Kao , Xiaochuan Pan

Purpose: The goal of this study is to develop a novel deep learning (DL) based reconstruction framework to improve the digital breast tomosynthesis (DBT) imaging performance. Methods: In this work, the DIR-DBTnet is developed for DBT image…

Medical Physics · Physics 2021-06-09 Ting Su , Xiaolei Deng , Zhenwei Wang , Jiecheng Yang , Jianwei Chen , Hairong Zheng , Dong Liang , Yongshuai Ge

There are a number of clinically relevant tasks in digital breast tomosynthesis (DBT) involving the detection and visual assessment of fiber-like structures such as Cooper's ligaments, blood vessels, and spiculated lesions. Such structures…

Medical Physics · Physics 2018-03-14 Sean D. Rose , Ingrid Reiser , Emil Y. Sidky , Xiaochuan Pan

Digital breast tomosynthesis (DBT) exams should utilize the lowest possible radiation dose while maintaining sufficiently good image quality for accurate medical diagnosis. In this work, we propose a convolution neural network (CNN) to…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Rodrigo de Barros Vimieiro , Chuang Niu , Hongming Shan , Lucas Rodrigues Borges , Ge Wang , Marcelo Andrade da Costa Vieira

Mammography-based screening has helped reduce the breast cancer mortality rate, but has also been associated with potential harms due to low specificity, leading to unnecessary exams or procedures, and low sensitivity. Digital breast…

Computer Vision and Pattern Recognition · Computer Science 2020-01-24 Sadanand Singh , Thomas Paul Matthews , Meet Shah , Brent Mombourquette , Trevor Tsue , Aaron Long , Ranya Almohsen , Stefano Pedemonte , Jason Su

Full Field Digital Mammograms (FFDMs) and Digital Breast Tomosynthesis (DBT) are the two most widely used imaging modalities for breast cancer screening. Although DBT has increased cancer detection compared to FFDM, its widespread adoption…

Computer Vision and Pattern Recognition · Computer Science 2024-08-19 Umang Sharma , Jungkyu Park , Laura Heacock , Sumit Chopra , Krzysztof Geras

Diffuse optical breast imaging utilizes near-infrared (NIR) light propagation through tissues to assess the optical properties of tissue for the identification of abnormal tissue. This optical imaging approach is sensitive, cost-effective,…

Medical Physics · Physics 2017-11-22 Wenxiang Cong , Xavier Intes , Ge Wang

Digital breast tomosynthesis is rapidly replacing digital mammography as the basic x-ray technique for evaluation of the breasts. However, the sparse sampling and limited angular range gives rise to different artifacts, which manufacturers…

Medical Physics · Physics 2018-08-15 Nikita Moriakov , Koen Michielsen , Jonas Adler , Ritse Mann , Ioannis Sechopoulos , Jonas Teuwen

Although digital breast tomosynthesis (DBT) improves diagnostic performance over full-field digital mammography (FFDM), false-positive recalls remain a concern in breast cancer screening. We developed a multi-modal artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2025-04-14 Jungkyu Park , Jan Witowski , Yanqi Xu , Hari Trivedi , Judy Gichoya , Beatrice Brown-Mulry , Malte Westerhoff , Linda Moy , Laura Heacock , Alana Lewin , Krzysztof J. Geras

Lesion detection in digital breast tomosynthesis (DBT) is an important and a challenging problem characterized by a low prevalence of images containing tumors. Due to the label scarcity problem, large deep learning models and…

Computer Vision and Pattern Recognition · Computer Science 2022-10-12 Yifan Zhang , Haoyu Dong , Nicholas Konz , Hanxue Gu , Maciej A. Mazurowski

Automated methods for breast cancer detection have focused on 2D mammography and have largely ignored 3D digital breast tomosynthesis (DBT), which is frequently used in clinical practice. The two key challenges in developing automated…

Computer Vision and Pattern Recognition · Computer Science 2020-02-28 Yu Zhang , Xiaoqin Wang , Hunter Blanton , Gongbo Liang , Xin Xing , Nathan Jacobs

Digital Breast Tomosynthesis (DBT) is an advanced breast imaging modality that offers superior lesion detection accuracy compared to conventional mammography, albeit at the trade-off of longer reading time. Accelerating lesion detection…

Computer Vision and Pattern Recognition · Computer Science 2024-07-26 Muhammad Alberb , Marawan Elbatel , Aya Elgebaly , Ricardo Montoya-del-Angel , Xiaomeng Li , Robert Martí
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