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This work proposes a procedure for designing algorithms for specific adaptive data collection tasks like active learning and pure-exploration multi-armed bandits. Unlike the design of traditional adaptive algorithms that rely on…

Machine Learning · Computer Science 2025-03-11 Jifan Zhang , Lalit Jain , Kevin Jamieson

Predictive simulations of complex systems are essential for applications ranging from weather forecasting to drug design. The veracity of these predictions hinges on their capacity to capture the effective system dynamics. Massively…

Computational Physics · Physics 2021-10-20 Pantelis R. Vlachas , Georgios Arampatzis , Caroline Uhler , Petros Koumoutsakos

Active learning is an established technique to reduce the labeling cost to build high-quality machine learning models. A core component of active learning is the acquisition function that determines which data should be selected to…

Machine Learning · Computer Science 2021-12-07 Yuejun Guo , Qiang Hu , Maxime Cordy , Mike Papadakis , Yves Le Traon

Predicting the adsorption affinity of a small molecule to a target surface is of importance to a range of fields, from catalysis to drug delivery and human safety, but a complex task to perform computationally when taking into account the…

Chemical Physics · Physics 2022-11-16 Ian Rouse , Vladimir Lobaskin

Accurate prediction of protein-ligand binding affinity is critical for drug discovery. While recent deep learning approaches have demonstrated promising results, they often rely solely on structural features of proteins and ligands,…

Machine Learning · Computer Science 2026-01-23 Han Liu , Keyan Ding , Peilin Chen , Yinwei Wei , Liqiang Nie , Dapeng Wu , Shiqi Wang

Model-free reinforcement learning based methods such as Proximal Policy Optimization, or Q-learning typically require thousands of interactions with the environment to approximate the optimum controller which may not always be feasible in…

Machine Learning · Computer Science 2019-05-16 Narendra Patwardhan , Zequn Wang

To address the computational challenges of ab initio molecular dynamics and the accuracy limitations of empirical force fields, the introduction of machine learning force fields has proven effective in various systems including metals and…

Soft Condensed Matter · Physics 2023-12-18 Junbao Hu , Liyang Zhou , Jian Jiang

Deep learning has made significant breakthroughs in many fields, including electroencephalogram (EEG) based brain-computer interfaces (BCIs). However, deep learning models are vulnerable to adversarial attacks, in which deliberately…

Machine Learning · Computer Science 2019-11-12 Xue Jiang , Xiao Zhang , Dongrui Wu

Large language models (LLMs) require reliable evaluation from pre-training to test-time scaling, making evaluation a recurring rather than one-off cost. As model scales grow and target tasks increasingly demand expert annotators, both the…

Artificial Intelligence · Computer Science 2026-05-20 Zeli Liu , Jiancheng Zhang , Cong Liu , Yinglun Zhu

Active learning can improve the efficiency of training prediction models by identifying the most informative new labels to acquire. However, non-response to label requests can impact active learning's effectiveness in real-world contexts.…

Machine Learning · Computer Science 2024-03-12 Thomas Robinson , Niek Tax , Richard Mudd , Ido Guy

We pose an active perception problem where an autonomous agent actively interacts with a second agent with potentially adversarial behaviors. Given the uncertainty in the intent of the other agent, the objective is to collect further…

Artificial Intelligence · Computer Science 2019-09-20 Macheng Shen , Jonathan P How

We study active preference learning as a framework for intuitively specifying the behaviour of autonomous robots. In active preference learning, a user chooses the preferred behaviour from a set of alternatives, from which the robot learns…

Robotics · Computer Science 2020-09-30 Nils Wilde , Dana Kulic , Stephen L. Smith

Intelligent systems have the ability to improve their behaviour over time taking observations, experiences or explicit feedback into account. Traditional approaches separate the learning problem and make isolated use of techniques from…

Machine Learning · Computer Science 2022-01-12 Simon Reichhuber , Sven Tomforde

Active learning aims to efficiently build a labeled training set by strategically selecting samples to query labels from annotators. In this sequential process, each sample acquisition influences subsequent selections, causing dependencies…

Machine Learning · Computer Science 2025-10-07 Beyza Kalkanli , Tales Imbiriba , Stratis Ioannidis , Deniz Erdogmus , Jennifer Dy

Active learning (AL) has emerged as a crucial strategy for reducing the prohibitive costs associated with medical image segmentation. However, standard uncertainty-based AL methods typically focus on maximizing performance metrics, ignoring…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Ghazal Danaee , Mélanie Gaillochet , Christian Desrosiers , Herve Lombaert , Sylvain Bouix

A multi-fidelity (MF) active learning method is presented for design optimization problems characterized by noisy evaluations of the performance metrics. Namely, a generalized MF surrogate model is used for design-space exploration,…

Optimization and Control · Mathematics 2022-07-12 Riccardo Pellegrini , Jeroen Wackers , Riccardo Broglia , Andrea Serani , Michel Visonneau , Matteo Diez

To identify a stationary action profile for a population of competitive agents, each executing private strategies, we introduce a novel active-learning scheme where a centralized external observer (or entity) can probe the agents' reactions…

Systems and Control · Electrical Eng. & Systems 2024-10-10 Filippo Fabiani , Alberto Bemporad

The performance of active learning algorithms can be improved in two ways. The often used and intuitive way is by reducing the overall error rate within the test set. The second way is to ensure that correct predictions are not forgotten…

Machine Learning · Computer Science 2024-11-19 Ryan Benkert , Mohit Prabhushankar , Ghassan AlRegib

Accurate prediction of protein-ligand interactions is essential for computer-aided drug discovery. However, existing methods often fail to capture solvent-dependent conformational changes and lack the ability to jointly learn multiple…

In addition to high accuracy, robustness is becoming increasingly important for machine learning models in various applications. Recently, much research has been devoted to improving the model robustness by training with noise…

Machine Learning · Computer Science 2021-03-30 Kun-Peng Ning , Lue Tao , Songcan Chen , Sheng-Jun Huang