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The recent success of large language models (LLMs) has sparked a growing interest in training large-scale models. As the model size continues to scale, concerns are growing about the depletion of high-quality, well-curated training data.…

Machine Learning · Computer Science 2025-11-18 Xuanyu Chen , Nan Yang , Shuai Wang , Dong Yuan

In recent years, Large Language Models (LLMs) have demonstrated exceptional proficiency across a broad spectrum of Natural Language Processing (NLP) tasks, including Machine Translation. However, previous methods predominantly relied on…

Existing Speech Language Model (SLM) scaling analysis paints a bleak picture. It predicts that SLMs require much more compute and data compared to text, leading some to question the feasibility of training high-quality SLMs. However, modern…

Computation and Language · Computer Science 2025-07-29 Gallil Maimon , Michael Hassid , Amit Roth , Yossi Adi

Proteins adopt multiple structural conformations to perform their diverse biological functions, and understanding these conformations is crucial for advancing drug discovery. Traditional physics-based simulation methods often struggle with…

Biomolecules · Quantitative Biology 2025-03-14 Jiarui Lu , Xiaoyin Chen , Stephen Zhewen Lu , Chence Shi , Hongyu Guo , Yoshua Bengio , Jian Tang

Instruction-fine-tuned large language models (LLMs) under 14B parameters continue to underperform on natural language understanding (NLU) tasks, often trailing smaller models like BERT-base on benchmarks such as GLUE and SuperGLUE.…

Computation and Language · Computer Science 2025-09-29 Bokai Hu , Sai Ashish Somayajula , Xin Pan , Pengtao Xie

Why do larger language models generalize better? To investigate this question, we develop generalization bounds on the pretraining objective of large language models (LLMs) in the compute-optimal regime, as described by the Chinchilla…

Machine Learning · Computer Science 2025-04-22 Marc Finzi , Sanyam Kapoor , Diego Granziol , Anming Gu , Christopher De Sa , J. Zico Kolter , Andrew Gordon Wilson

This paper explores the use of foundational large language models (LLMs) in hyperparameter optimization (HPO). Hyperparameters are critical in determining the effectiveness of machine learning models, yet their optimization often relies on…

Machine Learning · Computer Science 2024-11-12 Michael R. Zhang , Nishkrit Desai , Juhan Bae , Jonathan Lorraine , Jimmy Ba

LLM alignment ensures that large language models behave safely and effectively by aligning their outputs with human values, goals, and intentions. Aligning LLMs employ huge amounts of data, computation, and time. Moreover, curating data…

Machine Learning · Computer Science 2025-02-19 Amrit Khera , Rajat Ghosh , Debojyoti Dutta

Test-time scaling has emerged as a powerful technique for enhancing the reasoning capabilities of large language models. However, its effectiveness in medical reasoning remains uncertain, as the medical domain fundamentally differs from…

Computation and Language · Computer Science 2026-02-19 Xiaoke Huang , Juncheng Wu , Hui Liu , Xianfeng Tang , Yuyin Zhou

We surely enjoy the larger the better models for their superior performance in the last couple of years when both the hardware and software support the birth of such extremely huge models. The applied fields include text mining and others.…

Computation and Language · Computer Science 2024-06-04 Hanjuan Huang , Hao-Jia Song , Hsing-Kuo Pao

Scale is often attributed as one of the factors that cause an increase in the performance of LLMs, resulting in models with billion and trillion parameters. One of the limitations of such large models is the high computational requirements…

Machine Learning · Computer Science 2024-05-09 Sher Badshah , Hassan Sajjad

Large Language Models (LLMs) are large-scale pretrained models that have achieved remarkable success across diverse domains. These successes have been driven by unprecedented complexity and scale in both data and computations. However, due…

Large language models (LLMs) show promise for supporting clinical decision-making in complex fields such as rheumatology. Our evaluation shows that smaller language models (SLMs), combined with retrieval-augmented generation (RAG), achieve…

Computation and Language · Computer Science 2025-07-11 Sabine Felde , Rüdiger Buchkremer , Gamal Chehab , Christian Thielscher , Jörg HW Distler , Matthias Schneider , Jutta G. Richter

Reasoning is an integral part of many tasks performed by language models (LMs). However, the effects of scaling model sizes and data on reasoning abilities at pretraining time remain understudied. To rigorously investigate this problem, we…

Artificial Intelligence · Computer Science 2025-09-30 Xinyi Wang , Shawn Tan , Shenbo Xu , Mingyu Jin , William Yang Wang , Rameswar Panda , Yikang Shen

Large language models (LLMs) are increasingly explored for their reasoning capabilities, yet their ability to perform structured, constraint-based optimization from natural language remains insufficiently understood. This study evaluates…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-11-18 Aasish Kumar Sharma , Julian Kunkel

Large language models (LLMs) rely on pretraining on massive and heterogeneous corpora, where training data composition has a decisive impact on training efficiency and downstream generalization under realistic compute and data budget…

Computation and Language · Computer Science 2026-04-21 Zhuo Chen , Yuxuan Miao , Supryadi , Deyi Xiong

Large foundation models are typically trained on data from multiple domains, with the data mixture--the proportion of each domain used--playing a critical role in model performance. The standard approach to selecting this mixture relies on…

Machine Learning · Computer Science 2025-10-03 Mustafa Shukor , Louis Bethune , Dan Busbridge , David Grangier , Enrico Fini , Alaaeldin El-Nouby , Pierre Ablin

Fine-tuning large language models (LLMs) with limited data poses a practical challenge in low-resource languages, specialized domains, and constrained deployment settings. While pre-trained LLMs provide strong foundations, effective…

Computation and Language · Computer Science 2025-10-29 Marton Szep , Daniel Rueckert , Rüdiger von Eisenhart-Rothe , Florian Hinterwimmer

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

Computation and Language · Computer Science 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang