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Multimodal Fusion Learning (MFL), leveraging disparate data from various imaging modalities (e.g., MRI, CT, SPECT), has shown great potential for addressing medical problems such as skin cancer and brain tumor prediction. However, existing…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Joy Dhar , Nayyar Zaidi , Maryam Haghighat

Aims Late diagnosis of Oral Squamous Cell Carcinoma (OSCC) contributes significantly to its high global mortality rate, with over 50\% of cases detected at advanced stages and a 5-year survival rate below 50\% according to WHO statistics.…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Ajo Babu George , Sreehari J R Ajo Babu George , Sreehari J R Ajo Babu George , Sreehari J R

Breast cancer is one of the leading causes of death globally, and thus there is an urgent need for early and accurate diagnostic techniques. Although ultrasound imaging is a widely used technique for breast cancer screening, it faces…

Image and Video Processing · Electrical Eng. & Systems 2025-02-11 Pandiyaraju V , Shravan Venkatraman , Pavan Kumar S , Santhosh Malarvannan , Kannan A

Cancer research is increasingly driven by the integration of diverse data modalities, spanning from genomics and proteomics to imaging and clinical factors. However, extracting actionable insights from these vast and heterogeneous datasets…

Cancer is a leading cause of death worldwide, necessitating advancements in early detection and treatment technologies. In this paper, we present a novel and highly efficient melanoma detection framework that synergistically combines the…

Image and Video Processing · Electrical Eng. & Systems 2024-08-05 Peng Zhang , Divya Chaudhary

The use of machine learning (ML) for cancer staging through medical image analysis has gained substantial interest across medical disciplines. When accompanied by the innovative federated learning (FL) framework, ML techniques can further…

Machine Learning · Computer Science 2024-10-10 Kasra Borazjani , Naji Khosravan , Leslie Ying , Seyyedali Hosseinalipour

Multimodal clinical prediction is widely used to integrate heterogeneous data such as Electronic Health Records (EHR) and biosignals. However, existing methods tend to rely on static modality integration schemes and simple fusion…

Machine Learning · Computer Science 2026-01-16 Jongseok Kim , Seongae Kang , Jonghwan Shin , Yuhan Lee , Ohyun Jo

Survival analysis plays a vital role in making clinical decisions. However, the models currently in use are often difficult to interpret, which reduces their usefulness in clinical settings. Prototype learning presents a potential solution,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-08 Shuo Jiang , Zhuwen Chen , Liaoman Xu , Yanming Zhu , Changmiao Wang , Jiong Zhang , Feiwei Qin , Yifei Chen , Zhu Zhu

Accurately predicting molecular properties is a challenging but essential task in drug discovery. Recently, many mono-modal deep learning methods have been successfully applied to molecular property prediction. However, the inherent…

Machine Learning · Computer Science 2024-09-16 Xiaohua Lu , Liangxu Xie , Lei Xu , Rongzhi Mao , Shan Chang , Xiaojun Xu

Predicting patient features from single-cell data can help identify cellular states implicated in health and disease. Linear models and average cell type expressions are typically favored for this task for their efficiency and robustness,…

Machine Learning · Computer Science 2024-03-11 Jan P. Engelmann , Alessandro Palma , Jakub M. Tomczak , Fabian J. Theis , Francesco Paolo Casale

Whole-slide image classification represents a key challenge in computational pathology and medicine. Attention-based multiple instance learning (MIL) has emerged as an effective approach for this problem. However, the effect of attention…

Quantitative Methods · Quantitative Biology 2025-03-14 Rajiv Krishnakumar , Julien Baglio , Frederik F. Flöther , Christian Ruiz , Stefan Habringer , Nicole H. Romano

Multi-modal emotion recognition has garnered increasing attention as it plays a significant role in human-computer interaction (HCI) in recent years. Since different discrete emotions may exist at the same time, compared with single-class…

Machine Learning · Computer Science 2025-07-29 Chuhang Zheng , Chunwei Tian , Jie Wen , Daoqiang Zhang , Qi Zhu

Is there a way for a designer to evaluate the performance of a given hood frame geometry without spending significant time on simulation setup? This paper seeks to address this challenge by developing a multimodal machine-learning (MMML)…

Machine Learning · Computer Science 2025-09-16 Abhishek Indupally , Satchit Ramnath

Accurate breast lesion risk estimation can significantly reduce unnecessary biopsies and help doctors decide optimal treatment plans. Most existing computer-aided systems rely solely on mammogram features to classify breast lesions. While…

Image and Video Processing · Electrical Eng. & Systems 2021-08-24 Hung Q. Vo , Pengyu Yuan , Tiancheng He , Stephen T. C. Wong , Hien V. Nguyen

Automated segmentation of multiple sclerosis (MS) lesions using multicontrast magnetic resonance (MR) images improves efficiency and reproducibility compared to manual delineation, with deep learning (DL) methods achieving state-of-the-art…

Deep learning has become a powerful tool for medical image analysis; however, conventional Convolutional Neural Networks (CNNs) often fail to capture the fine-grained and complex features critical for accurate diagnosis. To address this…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Zahid Ullah , Minki Hong , Tahir Mahmood , Jihie Kim

The integration of deep learning in medical imaging has shown great promise for enhancing diagnostic, therapeutic, and research outcomes. However, applying universal models across multiple modalities remains challenging due to the inherent…

Image and Video Processing · Electrical Eng. & Systems 2024-12-30 Yixin Chen , Lin Gao , Yajuan Gao , Rui Wang , Jingge Lian , Xiangxi Meng , Yanhua Duan , Leiying Chai , Hongbin Han , Zhaoping Cheng , Zhaoheng Xie

Recent advances in Large Multi-modal Models (LMMs) have demonstrated their remarkable success as general-purpose multi-modal assistants, with particular focuses on holistic image- and video-language understanding. Conversely, less attention…

Computer Vision and Pattern Recognition · Computer Science 2025-11-11 Ye Liu , Zongyang Ma , Junfu Pu , Zhongang Qi , Yang Wu , Ying Shan , Chang Wen Chen

Recent advances in unified multimodal models (UMM) have demonstrated remarkable progress in both understanding and generation tasks. However, whether these two capabilities are genuinely aligned and integrated within a single model remains…

Computation and Language · Computer Science 2026-02-03 Chenlong Wang , Yuhang Chen , Zhihan Hu , Dongping Chen , Wenhu Chen , Sarah Wiegreffe , Tianyi Zhou

Deep-learning models based on whole-slide digital pathology images (WSIs) become increasingly popular for predicting molecular biomarkers. Instance-based models has been the mainstream strategy for predicting genetic alterations using WSIs…

Quantitative Methods · Quantitative Biology 2022-06-02 Bangwei Guo , Xingyu Li , Miaomiao Yang , Hong Zhang , Xu Steven Xu