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Bioprinting is an enabling biofabrication technique to create heterogeneous tissue constructs according to patient-specific geometries and compositions. Optimization of bioinks as per requirements for specific tissue applications is a…

Materials Science · Physics 2022-10-25 Abhinaba Banerjee , Sudipto Datta , Amit Roy Chowdhury , Pallab Datta

Response of the mechanoreceptors underlying the skin is greatly affected by its mechanical properties. Knowledge of this response is essential in designing artificial tactile devices such as minimally invasive tools and tactile displays.…

Tissues and Organs · Quantitative Biology 2018-08-31 Roozbeh Khodambashi , S. Najarian , A. T. Golpaygani , A. A. Dehkordi

In the present work, complex irregular bones and joints of the complete human arm were developed in a computer-aided design environment. Finite element analysis of an actual human arm was done to identify the distribution of stress using…

Tissues and Organs · Quantitative Biology 2018-07-11 Amit Kumar Bedaka , Ponnusamy Pandithevan

We develop a robust cut finite element method for a model of diffusion in fractured media consisting of a bulk domain with embedded cracks. The crack has its own pressure field and can cut through the bulk mesh in a very general fashion.…

Numerical Analysis · Mathematics 2020-06-03 Erik Burman , Peter Hansbo , Mats G. Larson

Pimple is one of the most common skin diseases for humans. The mechanical modeling of pimple growth is very limited. A finite element model is developed to quantify the deformation field with the expansion of follicle, and then the…

Medical Physics · Physics 2017-04-07 Xiangbiao Liao , Xiaobin Deng , LiangLiang Zhu , Feng Hao , Hang Xiao , Xiaoyang Shi , Xi Chen

This paper proposes a proof of concept application of a biphasic constitutive model to identify the mechanical properties of in vivo human skin under extension. Although poromechanics theory has been extensively used to model other soft…

We present a finite element modelling approach for unidirectional Fused Filament Fabrication (FFF)-printed specimens under tensile loading. In this study, the focus is on the fracture behaviour, the goal is to simulate the mechanical…

Computational Physics · Physics 2025-02-28 Simon Seibel , Josef Kiendl

A time-dependent modeling framework for autogenous self-healing concrete that couples moisture diffusion with damage evolution was developed. Water transport follows Fick's second law with a damage-dependent diffusivity obtained by…

Computational Engineering, Finance, and Science · Computer Science 2026-03-17 William Liu

A general approach to simulate the mechanical behavior of textile materials by taking into account all their constitutive elementary fibers and contacts between them is presented in this paper. A finite element code, based on an implicit…

Materials Science · Physics 2009-12-08 Damien Durville

The process of wound healing has been an active area of research around the world. The problem is the wounds of different patients heal differently. For example, patients with a background of diabetes may have difficulties in healing [1].…

Medical Physics · Physics 2022-09-15 Hy Dang

Finite element meshes for 3D models simulating realistic malignant melanoma (MM) growth, incorporating accurate dielectric properties of the skin, have been developed. Numerical simulations illustrate how 3D finite element meshes can be…

Numerical Analysis · Mathematics 2025-08-12 Eric Lindström , Larisa Beilina

The precise mechanisms underlying the failure of multi-phase materials may be strongly dependent on the material's microstructural morphology. Micromechanical modeling has provided much insight into this dependence, but uncertainties remain…

Materials Science · Physics 2016-04-14 T. W. J. de Geus , R. H. J. Peerlings , M. G. D. Geers

Wounds in epithelial tissues compromise their vital role in homeostasis. A rapid and efficient wound healing encompasses different mechanisms, which includes the formation of a contractile actin-myosin cable around its edge, known as the…

Soft Condensed Matter · Physics 2024-03-22 R. F. Almada , N. A. M. Araujo , P. Patricio

This study presents a mathematical model formulated as a system of first-order non-linear ordinary differential equations, aimed at examining the effects of different factors, classified as local and systemic factors on a wound healing…

Other Quantitative Biology · Quantitative Biology 2025-09-16 Alinafe Maenje , Joseph Malinzi

When modelling discontinuities (interfaces) using the finite element method, the standard approach is to use a conforming finite-element mesh in which the mesh matches the interfaces. However, this approach can prove cumbersome if the…

Computational Engineering, Finance, and Science · Computer Science 2024-06-06 Jedrzej Dobrzanski , Kajetan Wojtacki , Stanislaw Stupkiewicz

The developed computational approach is capable of initiating and propagating cracks inside materials and along material interfaces of general multi-domain structures under quasi-static conditions. Special attention is paid to particular…

Computational Engineering, Finance, and Science · Computer Science 2023-08-23 Roman Vodička

Diabetic foot ulcers are triggered by mechanical loadings applied to the surface of the plantar skin. Strain is considered to play a crucial role in relation to ulcer etiology and can be assessed by Finite Element (FE) modelling. A…

Medical Physics · Physics 2023-07-19 Alessio Trebbi , Nolwenn Fougeron , Yohan Payan

In this paper we propose a novel coupled poroelasticity-diffusion model for the formation of extracellular oedema and infectious myocarditis valid in large deformations, manifested as an interaction between interstitial flow and the…

The modeling of damage processes in materials constitutes an ill-posed mathematical problem which manifests in mesh-dependent finite element results. The loss of ellipticity of the discrete system of equations is counteracted by…

Computational Engineering, Finance, and Science · Computer Science 2021-02-18 Philipp Junker , Johannes Riesselmann , Daniel Balzani

Pressure ulcers are a severe disease affecting patients that are bedridden or in a wheelchair bound for long periods of time. These wounds can develop in the deep layers of the skin of specific parts of the body, mostly on heels or sacrum,…

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