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A microfluidic device is constructed from PDMS with a single channel having a short section that is a thin flexible membrane, in order to investigate the complex fluid-structure interaction that arises between a flowing fluid and a…

Soft Condensed Matter · Physics 2020-07-03 Debadi Chakraborty , J. Ravi Prakash , Leslie Yeo , James Friend

Microfluidic multipoles (MFMs) have been realized experimentally and hold promise for "open-space" biological and chemical surface processing. Whereas convective flow can readily be predicted using hydraulic-electrical analogies, the design…

Biological systems achieve precise control over ambient fluids through the self-organization of active protein structures including flagella, cilia, and cytoskeletal networks. In active structures individual proteins consume chemical energy…

Microfluidic valves play a key role within microfluidic systems by regulating fluid flow through distinct microchannels, enabling many advanced applications in medical diagnostics, lab-on-chips, and laboratory automation. While microfluidic…

Materials Science · Physics 2023-12-19 Tinku Supakar , David Space , Sophy Meija , Rou Yu Tan , Jeffrey R. Alston , Eric A. Josephs

Modern micromanipulation techniques typically involve trapping using electromagnetic, acoustic or flow fields that produce stresses on the trapped particles thereby precluding stress-free manipulations. Here, we show that by employing…

Fluid Dynamics · Physics 2024-06-13 Jeremias Gonzalez , Ajay Gopinathan , Bin Liu

Strong control over experimental conditions in microfluidic channels provides a unique opportunity to study and optimize membraneless microbial fuel cells (MFCs), particularly with respect to the role of flow. However, improved performance…

In this study, capillary-driven flow of different pure liquids and diluted bitumen samples were studied using microfluidic channel (width of 30 um and depth of 9 um). Capillary filling kinetics of liquids as a function of time were…

Soft Condensed Matter · Physics 2016-12-01 Kiarash Keshmiri , Saeed Mozaffari , Plamen Tchoukov , Haibo Huang , Neda Nazemifard

Self-organization of kinesin-driven, microtubule-based 3D active fluids relies on the collective dynamics of single microtubules. However, the connection between macroscopic fluid flows and microscopic motion of microtubules remains…

Soft Condensed Matter · Physics 2019-04-29 Teagan E. Bate , Edward J. Jarvis , Megan E. Varney , Kun-Ta Wu

Flows of particles through bottlenecks are ubiquitous in nature and industry, involving both dry granular materials and suspensions. However, practical limitations of conventional experimental setups hinder the full understanding of these…

Soft Condensed Matter · Physics 2025-07-02 Lars Kool , Jules Tampier , Philippe Bourrianne , Anke Lindner

Flows enabled by phoretic mechanisms are of significant interest in several biological and biomedical processes, such as bacterial motion and targeted drug delivery. Here, we develop a homogenization-based macroscopic boundary condition…

Recent numerical analyses to optimize the design of microfluidic devices for more effective entrapment or segregation of surrogate circulating tumor cells (CTCs) from healthy cells have been reported in the literature without concurrently…

Computational Physics · Physics 2020-06-23 Hakan Başağaoğlu , Justin Blount , Sauro Succi , Christopher J. Freitas

Recent progress in colloidal science has led to elaborate self-assembled structures whose complexity raises hopes for elaborating new materials. However, the throughputs are extremely low and consequently, the chance to produce materials of…

Soft Condensed Matter · Physics 2014-09-16 Bingqing Shen , Joshua Ricouvier , Mathilde Reyssat , Florent Malloggi , Patrick Tabeling

Artificial microswimmers are a new technology with promising microfluidics and biomedical applications, such as directed cargo transport, microscale assembly, and targeted drug delivery. A fundamental barrier to realising this potential is…

Fluid Dynamics · Physics 2018-06-27 Thomas D. Montenegro-Johnson

Ultrasound-vaporizable microdroplets can be exploited for targeted drug delivery. However, it requires customized microfluidic techniques able to produce monodisperse, capillary-sized and biocompatible multiple emulsions. Recent development…

Soft Condensed Matter · Physics 2019-12-17 E. Teston , V. Hingot , V. Faugeras , C. Errico , M. Bezagu , M. Tanter , O. Couture

Two dimensional active fluids display a transition from turbulent to coherent flow upon decreasing the size of the confining geometry. A recent experiment suggests that the behavior in three dimensions is remarkably different; emergent…

Soft Condensed Matter · Physics 2021-08-17 Minu Varghese , Arvind Baskaran , Michael Hagan , Aparna Baskaran

Syringe pumps are widely used biomedical equipment which offer low-cost solutions to drive and control flow through microfluidic chips. However, they have been shown to transmit mechanical oscillations resulting from their stepper motors,…

Fluid Dynamics · Physics 2024-06-19 Md Ehtashamul Haque , Amirali Matin , Xu Wang , Maïwenn Kersaudy-Kerhoas

Semiconductor microelectronics are emerging as a powerful tool for building smart, autonomous robots too small to see with the naked eye. Yet a number of existing microrobot platforms, despite significant advantages in speed, robustness,…

Robotics · Computer Science 2024-11-15 Lucas C. Hanson , William H. Reinhardt , Scott Shrager , Tarunyaa Sivakumar , Marc Z. Miskin

Alternative computing approaches that interface readily with physical systems are well suited for embedded control of those systems. We demonstrate finite state machines implemented as pneumatic circuits of microfluidic valves, and we…

Emerging Technologies · Computer Science 2023-09-18 Siavash Ahrar , Manasi Raje , Irene C. Lee , Elliot E. Hui

Microfluidic devices manufactured from soft polymeric materials have emerged as a paradigm for cheap, disposable and easy-to-prototype fluidic platforms for integrating chemical and biological assays and analyses. The interplay between the…

Soft Condensed Matter · Physics 2021-11-25 Ivan C. Christov

This article describes the design and manufacturing of a microfluidic chip, allowing for the actuation of a gas-liquid interface and of the neighboring fluid. A first way to control the interface motion is to apply a pressure difference…

Soft Condensed Matter · Physics 2010-01-04 Jie Xu , Daniel Attinger