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Pathological is crucial to cancer diagnosis. Usually, Pathologists draw their conclusion based on observed cell and tissue structure on histology slides. Rapid development in machine learning, especially deep learning have established…

Image and Video Processing · Electrical Eng. & Systems 2020-01-15 Jiangbo Shi , Zeyu Gao , Haichuan Zhang , Pargorn Puttapirat , Chunbao Wang , Xiangrong Zhang , Chen Li

Neural networks promise to bring robust, quantitative analysis to medical fields, but adoption is limited by the technicalities of training these networks. To address this translation gap between medical researchers and neural networks in…

Image and Video Processing · Electrical Eng. & Systems 2019-02-20 Brendon Lutnick , Brandon Ginley , Darshana Govind , Sean D. McGarry , Peter S. LaViolette , Rabi Yacoub , Sanjay Jain , John E. Tomaszewski , Kuang-Yu Jen , Pinaki Sarder

Supervised Deep Learning has been highly successful in recent years, achieving state-of-the-art results in most tasks. However, with the ongoing uptake of such methods in industrial applications, the requirement for large amounts of…

Computer Vision and Pattern Recognition · Computer Science 2019-07-18 Fabio De Sousa Ribeiro , Francesco Caliva , Mark Swainson , Kjartan Gudmundsson , Georgios Leontidis , Stefanos Kollias

The large number of trainable parameters of deep neural networks renders them inherently data hungry. This characteristic heavily challenges the medical imaging community and to make things even worse, many imaging modalities are ambiguous…

Neural and Evolutionary Computing · Computer Science 2017-11-29 Simon Kohl , David Bonekamp , Heinz-Peter Schlemmer , Kaneschka Yaqubi , Markus Hohenfellner , Boris Hadaschik , Jan-Philipp Radtke , Klaus Maier-Hein

AI-based diagnoses have demonstrated dermatologist-level performance in classifying skin cancer. However, such systems are prone to under-performing when tested on data from minority groups that lack sufficient representation in the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-31 Janet Wang , Yunsung Chung , Zhengming Ding , Jihun Hamm

Artificial Intelligence (AI) is now firmly at the center of evidence-based medicine. Despite many success stories that edge the path of AI's rise in healthcare, there are comparably many reports of significant shortcomings and unexpected…

Pre-biopsy magnetic resonance imaging (MRI) is increasingly used to target suspicious prostate lesions. This has led to artificial intelligence (AI) applications improving MRI-based detection of clinically significant prostate cancer…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Hassan Jahanandish , Shengtian Sang , Cynthia Xinran Li , Sulaiman Vesal , Indrani Bhattacharya , Jeong Hoon Lee , Richard Fan , Geoffrey A. Sonna , Mirabela Rusu

Whole gland (WG) segmentation of the prostate plays a crucial role in detection, staging and treatment planning of prostate cancer (PCa). Despite promise shown by deep learning (DL) methods, they rely on the availability of a considerable…

Image and Video Processing · Electrical Eng. & Systems 2021-07-23 Alvaro Fernandez-Quilez , Steinar Valle Larsen , Morten Goodwin , Thor Ole Gulsurd , Svein Reidar Kjosavik , Ketil Oppedal

In the field of image classification, existing methods often struggle with biased or ambiguous data, a prevalent issue in real-world scenarios. Current strategies, including semi-supervised learning and class blending, offer partial…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Lars Schmarje , Vasco Grossmann , Claudius Zelenka , Johannes Brünger , Reinhard Koch

Background: Bayesian Networks (BNs) are probabilistic graphical models that leverage Bayes' theorem to portray dependencies and cause-and-effect relationships between variables. These networks have gained prominence in the field of health…

Artificial intelligence (AI) techniques for image-based segmentation have garnered much attention in recent years. Convolutional neural networks (CNNs) have shown impressive results and potential towards fully automated segmentation in…

Medical Physics · Physics 2021-11-17 Fereshteh Yousefirizi , Abhinav K. Jha , Julia Brosch-Lenz , Babak Saboury , Arman Rahmim

The rapid proliferation of AI-generated images, powered by generative adversarial networks (GANs), diffusion models, and other synthesis techniques, has raised serious concerns about misinformation, copyright violations, and digital…

Computer Vision and Pattern Recognition · Computer Science 2026-03-31 Nusrat Tasnim , Kutub Uddin , Khalid Malik

The Gleason scoring system is the primary diagnostic and prognostic tool for prostate cancer. In recent years, with the development of digitisation devices, the use of computer vision techniques for the analysis of biopsies has increased.…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Julio Silva-Rodríguez , Adrián Colomer , María A. Sales , Rafael Molina , Valery Naranjo

While perception tasks such as visual object recognition and text understanding play an important role in human intelligence, the subsequent tasks that involve inference, reasoning and planning require an even higher level of intelligence.…

Machine Learning · Statistics 2016-09-06 Hao Wang , Dit-Yan Yeung

Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…

Enhancing the robustness of deep learning models against adversarial attacks is crucial, especially in critical domains like healthcare where significant financial interests heighten the risk of such attacks. Whole slide images (WSIs) are…

Computer Vision and Pattern Recognition · Computer Science 2024-03-22 Saba Heidari Gheshlaghi , Milan Aryal , Nasim Yahyasoltani , Masoud Ganji

There is a dire need for medical imaging datasets with accompanying annotations to perform downstream patient analysis. However, it is difficult to manually generate these annotations, due to the time-consuming nature, and the variability…

Image and Video Processing · Electrical Eng. & Systems 2024-06-21 Deepa Krishnaswamy , Vamsi Krishna Thiriveedhi , Cosmin Ciausu , David Clunie , Steve Pieper , Ron Kikinis , Andrey Fedorov

In Canada, prostate cancer is the most common form of cancer in men and accounted for 20% of new cancer cases for this demographic in 2022. Due to recent successes in leveraging machine learning for clinical decision support, there has been…

Image and Video Processing · Electrical Eng. & Systems 2023-12-01 Aditya Sridhar , Chi-en Amy Tai , Hayden Gunraj , Yuhao Chen , Alexander Wong

Purpose: Machine learning is broadly used for clinical data analysis. Before training a model, a machine learning algorithm must be selected. Also, the values of one or more model parameters termed hyper-parameters must be set. Selecting…

Machine Learning · Computer Science 2018-12-10 Xueqiang Zeng , Gang Luo