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The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

Computation and Language · Computer Science 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi

The current work investigates the capability of Large language models (LLMs) that are explicitly trained on large corpuses of medical knowledge (Med-PaLM 2) to predict psychiatric functioning from patient interviews and clinical…

Computation and Language · Computer Science 2023-08-04 Isaac R. Galatzer-Levy , Daniel McDuff , Vivek Natarajan , Alan Karthikesalingam , Matteo Malgaroli

Automated depression diagnosis aims to analyze multimodal information from interview videos to predict participants' depression scores. Previous studies often lack clear explanations of how these scores were determined, limiting their…

Artificial Intelligence · Computer Science 2026-03-19 Wei Zhang , Juan Chen , En Zhu , Wenhong Cheng , YunPeng Li , Yanbo J. Wang

Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient…

Computation and Language · Computer Science 2025-01-03 Kaushik Roy , Harshul Surana , Darssan Eswaramoorthi , Yuxin Zi , Vedant Palit , Ritvik Garimella , Amit Sheth

Psychological constructs within individuals are widely believed to be interconnected. We investigated whether and how Large Language Models (LLMs) can model the correlational structure of human psychological traits from minimal quantitative…

Artificial Intelligence · Computer Science 2026-03-24 Yi-Fei Liu , Yi-Long Lu , Di He , Hang Zhang

In psychological practices, standardized questionnaires serve as essential tools for assessing mental health through structured, clinically-validated questions (i.e., items). While social media platforms offer rich data for mental health…

Computation and Language · Computer Science 2025-06-03 Federico Ravenda , Seyed Ali Bahrainian , Andrea Raballo , Antonietta Mira , Noriko Kando

Mental health has attracted substantial attention in recent years and LLM can be an effective technology for alleviating this problem owing to its capability in text understanding and dialogue. However, existing research in this domain…

Computation and Language · Computer Science 2024-12-09 Jinpeng Hu , Tengteng Dong , Luo Gang , Hui Ma , Peng Zou , Xiao Sun , Dan Guo , Xun Yang , Meng Wang

Psychological support hotlines provide critical support for individuals experiencing mental health emergencies, yet current assessments largely rely on human operators whose judgments may vary with professional experience and are…

Computation and Language · Computer Science 2026-05-12 Terumi Chiba , Yang Luo , Ziyun Cui , Yongsheng Tong , Chao Zhang

Large Language Models (LLMs) have demonstrated exceptional capabilities in solving various tasks, progressively evolving into general-purpose assistants. The increasing integration of LLMs into society has sparked interest in whether they…

Computation and Language · Computer Science 2025-10-20 Yuan Li , Yue Huang , Hongyi Wang , Ying Cheng , Xiangliang Zhang , James Zou , Lichao Sun

Standardized, validated questionnaires are vital tools in research and healthcare, offering dependable self-report data. Prior work has revealed that virtual agent-administered questionnaires are almost equivalent to self-administered ones…

Human-Computer Interaction · Computer Science 2024-07-09 Hye Sun Yun , Mehdi Arjmand , Phillip Sherlock , Michael K. Paasche-Orlow , James W. Griffith , Timothy Bickmore

The advent of large language models (LLMs) has significantly advanced various fields, including natural language processing and automated dialogue systems. This paper explores the application of LLMs in psychological counseling, addressing…

Computation and Language · Computer Science 2024-06-21 Wenjie Li , Tianyu Sun , Kun Qian , Wenhong Wang

Background: Advancements in large language models (LLMs) have opened new possibilities in psychiatric interviews, an underexplored area where LLMs could be valuable. This study focuses on enhancing psychiatric interviews by analyzing…

Artificial Intelligence · Computer Science 2025-02-11 Jae-hee So , Joonhwan Chang , Eunji Kim , Junho Na , JiYeon Choi , Jy-yong Sohn , Byung-Hoon Kim , Sang Hui Chu

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

This paper compares the effectiveness of traditional machine learning methods, encoder-based models, and large language models (LLMs) on the task of detecting depression and anxiety. Five Russian-language datasets were considered, each…

Computation and Language · Computer Science 2025-11-04 Gleb Kuzmin , Petr Strepetov , Maksim Stankevich , Natalia Chudova , Artem Shelmanov , Ivan Smirnov

Large language models (LLMs) have offered new opportunities for emotional support, and recent work has shown that they can produce empathic responses to people in distress. However, long-term mental well-being requires emotional…

Computation and Language · Computer Science 2024-08-09 Hongli Zhan , Allen Zheng , Yoon Kyung Lee , Jina Suh , Junyi Jessy Li , Desmond C. Ong

Large Language Models (LLMs) such as ChatGPT have shown remarkable abilities in producing human-like text. However, it is unclear how accurately these models internalize concepts that shape human thought and behavior. Here, we developed a…

Machine Learning · Computer Science 2025-07-01 Hiro Taiyo Hamada , Ippei Fujisawa , Genji Kawakita , Yuki Yamada

As demand for mental health care outpaces clinician-delivered assessment, scalable screening tools are increasingly needed. Large language models (LLMs) may identify psychiatric risk from patient narratives, but their reliability across…

Computation and Language · Computer Science 2026-05-26 Jianfeng Zhu , Megan Korhummel , Ruoming Jin , Karin G. Coifman

The demand for psychological counselling has grown significantly in recent years, particularly with the global outbreak of COVID-19, which has heightened the need for timely and professional mental health support. Online psychological…

Computation and Language · Computer Science 2023-09-04 Tin Lai , Yukun Shi , Zicong Du , Jiajie Wu , Ken Fu , Yichao Dou , Ziqi Wang

Advances in large language models (LLMs) have enabled a wide range of applications. However, depression prediction is hindered by the lack of large-scale, high-quality, and rigorously annotated datasets. This study introduces DepressLLM,…

Computation and Language · Computer Science 2025-08-13 Sehwan Moon , Aram Lee , Jeong Eun Kim , Hee-Ju Kang , Il-Seon Shin , Sung-Wan Kim , Jae-Min Kim , Min Jhon , Ju-Wan Kim
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