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Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…

Machine Learning · Computer Science 2026-01-30 Yiying Sheng , Wenhao Ding , Dylan Roi , Leonard Leong Litt Yeo , Hwa Liang Leo , Choon Hwai Yap

Mathematical oncology provides unique and invaluable insights into tumour growth on both the microscopic and macroscopic levels. This review presents state-of-the-art modelling techniques and focuses on their role in understanding…

Diffusion magnetic resonance imaging (dMRI) is a crucial non-invasive technique for exploring the microstructure of the living human brain. Traditional hand-crafted and model-based tissue microstructure reconstruction methods often require…

Image and Video Processing · Electrical Eng. & Systems 2025-02-26 Xinrui Ma , Jian Cheng , Wenxin Fan , Ruoyou Wu , Yongquan Ye , Shanshan Wang

Early cancer detection remains one of the most critical challenges in modern healthcare, where delayed diagnosis significantly reduces survival outcomes. Recent advancements in artificial intelligence, particularly deep learning, have…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Emmanuella Avwerosuoghene Oghenekaro

In recent years, deep learning models have been applied to neuroimaging data for early diagnosis of Alzheimer's disease (AD). Structural magnetic resonance imaging (sMRI) and positron emission tomography (PET) images provide structural and…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Yanteng Zhanga , Xiaohai He , Yi Hao Chan , Qizhi Teng , Jagath C. Rajapakse

Comprehending the interplay between spatial and temporal characteristics of neural dynamics can contribute to our understanding of information processing in the human brain. Graph neural networks (GNNs) provide a new possibility to…

Neurons and Cognition · Quantitative Biology 2022-04-29 Simon Wein , Alina Schüller , Ana Maria Tomé , Wilhelm M. Malloni , Mark W. Greenlee , Elmar W. Lang

Glioblastoma Multiforme is a malignant brain tumor with poor prognosis. There have been numerous attempts to model the invasion of tumorous glioma cells via partial differential equations in the form of advection-diffusion-reaction…

Cell Behavior · Quantitative Biology 2020-01-16 Christian Engwer , Michael Wenske

Diffusion MRI (dMRI) angular super-resolution (ASR) aims to reconstruct high-angular-resolution (HAR) signals from limited low-angular-resolution (LAR) data without prolonging scan time. However, existing methods are limited in recovering…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 Mu Nan , Taohui Xiao , Ruoyou Wu , Shoujun Yu , Ye Li , Hairong Zheng , Shanshan Wang

The Blood-Oxygen-Level-Dependent (BOLD) signal of resting-state fMRI (rs-fMRI) records the temporal dynamics of intrinsic functional networks in the brain. However, existing deep learning methods applied to rs-fMRI either neglect the…

Machine Learning · Computer Science 2021-06-30 Soham Gadgil , Qingyu Zhao , Adolf Pfefferbaum , Edith V. Sullivan , Ehsan Adeli , Kilian M. Pohl

Spatiotemporal graph neural networks (ST-GNNs) are powerful tools for modeling spatial and temporal data dependencies. However, their applications have been limited primarily to small-scale datasets because of memory constraints. While…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-17 Seth Ockerman , Amal Gueroudji , Tanwi Mallick , Yixuan He , Line Pouchard , Robert Ross , Shivaram Venkataraman

Deep Recurrent Neural Network architectures, though remarkably capable at modeling sequences, lack an intuitive high-level spatio-temporal structure. That is while many problems in computer vision inherently have an underlying high-level…

Computer Vision and Pattern Recognition · Computer Science 2016-04-12 Ashesh Jain , Amir R. Zamir , Silvio Savarese , Ashutosh Saxena

Accurate differentiation of pseudoprogression (PsP) from True Progression (TP) following radiotherapy (RT) in glioblastoma (GBM) patients is crucial for optimal treatment planning. However, this task remains challenging due to the…

Advances in spatial transcriptomics (ST) technologies enable systematic molecular characterization of tumor microenvironment, tumor gradients and gene regulatory networks. Cancer progression is known to vary along pathological gradients,…

Diffusion MRI tractography technique enables non-invasive visualization of the white matter pathways in the brain. It plays a crucial role in neuroscience and clinical fields by facilitating the study of brain connectivity and neurological…

Computer Vision and Pattern Recognition · Computer Science 2025-03-06 Yiqiong Yang , Yitian Yuan , Baoxing Ren , Ye Wu , Yanqiu Feng , Xinyuan Zhang

Differentiating true tumor progression (TP) from treatment-related pseudoprogression (PsP) in glioblastoma remains challenging, especially at early follow-up. We present the first stage-specific, cross-sectional benchmarking of deep…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Wenhao Guo , Golrokh Mirzaei

Cardiac computed tomography (CT) has emerged as a major imaging modality for the diagnosis and monitoring of cardiovascular diseases. High temporal resolution is essential to ensure diagnostic accuracy. Limited-angle data acquisition can…

Image and Video Processing · Electrical Eng. & Systems 2025-03-12 Shuo Han , Yongshun Xu , Dayang Wang , Bahareh Morovati , Li Zhou , Jonathan S. Maltz , Ge Wang , Hengyong Yu

Purpose: Magnetic Resonance Imaging (MRI) enables non-invasive assessment of brain abnormalities during early life development. Permanent magnet scanners operating in the neonatal intensive care unit (NICU) facilitate MRI of sick infants,…

Image and Video Processing · Electrical Eng. & Systems 2025-05-23 Yamin Arefeen , Brett Levac , Bhairav Patel , Chang Ho , Jonathan I. Tamir

Tomography medical imaging is essential in the clinical workflow of modern cancer radiotherapy. Radiation oncologists identify cancerous tissues, applying delineation on treatment regions throughout all image slices. This kind of task is…

Computer Vision and Pattern Recognition · Computer Science 2019-04-08 Chun-Hung Chao , Yen-Chi Cheng , Hsien-Tzu Cheng , Chi-Wen Huang , Tsung-Ying Ho , Chen-Kan Tseng , Le Lu , Min Sun

Parameters in mathematical models for glioblastoma multiforme (GBM) tumour growth are highly patient specific. Here we aim to estimate parameters in a Cahn-Hilliard type diffuse interface model in an optimised way using model order…

Numerical Analysis · Mathematics 2023-07-19 Abramo Agosti , Pasquale Ciarletta , Harald Garcke , Michael Hinze

Latent diffusion models (LDMs) have recently achieved strong performance in 3D medical image synthesis. However, modalities like cine cardiac MRI (CMR), representing a temporally synchronized 3D volume across the cardiac cycle, add an…