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Glioma is a common malignant brain tumor with distinct survival among patients. The isocitrate dehydrogenase (IDH) gene mutation provides critical diagnostic and prognostic value for glioma. It is of crucial significance to non-invasively…

Image and Video Processing · Electrical Eng. & Systems 2021-09-13 Yiran Wei , Yonghao Li , Xi Chen , Carola-Bibiane Schönlieb , Chao Li , Stephen J. Price

Precise molecular subtyping of gliomas, including isocitrate dehydrogenase (IDH) mutation and 1p/19q codeletion, directly guides surgical and therapeutic decisions, yet currently relies on invasive tissue sampling. Deep learning on…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Han Jang , Junhyeok Lee , Heeseong Eum , Joon Jang , Yoseob Han , Seung Hong Choi , Kyu Sung Choi

Glioma, an aggressive brain malignancy characterized by rapid progression and its poor prognosis, poses significant challenges for accurate evolution prediction. These challenges are exacerbated by sparse, irregularly acquired longitudinal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Aghiles Kebaili , Romain Modzelewski , Jérôme Lapuyade-Lahorgue , Maxime Fontanilles , Sébastien Thureau , Su Ruan

The isocitrate dehydrogenase (IDH) gene mutation is an essential biomarker for the diagnosis and prognosis of glioma. It is promising to better predict glioma genotype by integrating focal tumor image and geometric features with brain…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yiran Wei , Xi Chen , Lei Zhu , Lipei Zhang , Carola-Bibiane Schönlieb , Stephen J. Price , Chao Li

Perfusion-weighted magnetic resonance imaging (MRI) is an imaging technique that allows one to measure tissue perfusion in an organ of interest through the injection of an intravascular paramagnetic contrast agent (CA). Due to a preference…

Computer Vision and Pattern Recognition · Computer Science 2017-08-28 Cagdas Ulas , Christine Preibisch , Jonathan Sperl , Thomas Pyka , Jayashree Kalpathy-Cramer , Bjoern Menze

Predicting the spatio-temporal progression of brain tumors is essential for guiding clinical decisions in neuro-oncology. We propose a hybrid mechanistic learning framework that combines a mathematical tumor growth model with a guided…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Daria Laslo , Efthymios Georgiou , Marius George Linguraru , Andreas Rauschecker , Sabine Muller , Catherine R. Jutzeler , Sarah Bruningk

The isocitrate dehydrogenase (IDH) gene mutation status is an important biomarker for glioma patients. The gold standard of IDH mutation detection requires tumour tissue obtained via invasive approaches and is usually expensive. Recent…

Machine Learning · Computer Science 2022-01-17 Yiran Wei , Chao Li , Xi Chen , Carola-Bibiane Schönlieb , Stephen J. Price

Gliomas are brain tumor types that have a high mortality rate which means early and accurate diagnosis is important for therapeutic intervention for the tumors. To address this difficulty, the proposed research will develop a hybrid deep…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Pandiyaraju V , Sreya Mynampati , Abishek Karthik , Poovarasan L , D. Saraswathi

Diffuse gliomas are malignant brain tumors that grow widespread through the brain. The complex interactions between neoplastic cells and normal tissue, as well as the treatment-induced changes often encountered, make glioma tumor growth…

Current treatment planning of patients diagnosed with a brain tumor, such as glioma, could significantly benefit by accessing the spatial distribution of tumor cell concentration. Existing diagnostic modalities, e.g. magnetic resonance…

Graph neural networks (GNNs) have been successfully applied to early mild cognitive impairment (EMCI) detection, with the usage of elaborately designed features constructed from blood oxygen level-dependent (BOLD) time series. However, few…

Machine Learning · Computer Science 2022-11-14 Yunpeng Zhao , Fugen Zhou , Bin Guo , Bo Liu

Understanding and predicting the progression of neurodegenerative diseases remains a major challenge in medical AI, with significant implications for early diagnosis, disease monitoring, and treatment planning. However, most available…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Nivetha Jayakumar , Swakshar Deb , Bahram Jafrasteh , Qingyu Zhao , Miaomiao Zhang

Early detection of brain tumors through magnetic resonance imaging (MRI) is essential for timely treatment, yet access to diagnostic facilities remains limited in remote areas. Gliomas, the most common primary brain tumors, arise from the…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Khush Mendiratta , Shweta Singh , Pratik Chattopadhyay

DSC-MRI perfusion is a medical imaging technique for diagnosing and prognosing brain tumors and strokes. Its analysis relies on mathematical deconvolution, but noise or motion artifacts in a clinical environment can disrupt this process,…

Quantitative Methods · Quantitative Biology 2025-10-17 Pierre Fayolle , Alexandre Bône , Noëlie Debs , Mathieu Naudin , Pascal Bourdon , Remy Guillevin , David Helbert

Dynamic susceptibility contrast magnetic resonance imaging (DSC-MRI) is widely used to evaluate acute ischemic stroke to distinguish salvageable tissue and infarct core. For this purpose, traditional methods employ deconvolution techniques,…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Anbo Cao , Pin-Yu Le , Zhonghui Qie , Haseeb Hassan , Yingwei Guo , Asim Zaman , Jiaxi Lu , Xueqiang Zeng , Huihui Yang , Xiaoqiang Miao , Taiyu Han , Guangtao Huang , Yan Kang , Yu Luo , Jia Guo

PET imaging is widely employed for observing biological metabolic activities within the human body. However, numerous benign conditions can cause increased uptake of radiopharmaceuticals, confounding differentiation from malignant tumors.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Ran Hong , Yuxia Huang , Lei Liu , Zhonghui Wu , Bingxuan Li , Xuemei Wang , Qiegen Liu

Isocitrate DeHydrogenase (IDH) mutation status is a crucial biomarker for glioma prognosis. However, current prediction methods are limited by the low availability and noise of functional MRI. Structural and morphological connectomes offer…

Computer Vision and Pattern Recognition · Computer Science 2025-08-14 Haotian Tang , Jianwei Chen , Xinrui Tang , Yunjia Wu , Zhengyang Miao , Chao Li

The ability to estimate how a tumor might evolve in the future could have tremendous clinical benefits, from improved treatment decisions to better dose distribution in radiation therapy. Recent work has approached the glioma growth…

Generating realistic images to accurately predict changes in the structure of brain MRI is a crucial tool for clinicians. Such applications help assess patients' outcomes and analyze how diseases progress at the individual level. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Mattia Litrico , Francesco Guarnera , Valerio Giuffirda , Daniele Ravì , Sebastiano Battiato

Simultaneous modeling of the spatio-temporal variation patterns of brain functional network from 4D fMRI data has been an important yet challenging problem for the field of cognitive neuroscience and medical image analysis. Inspired by the…

Computer Vision and Pattern Recognition · Computer Science 2021-03-24 Yu Zhao , Xiang Li , Wei Zhang , Shijie Zhao , Milad Makkie , Mo Zhang , Quanzheng Li , Tianming Liu
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