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Although there is significant progress in supervised semantic segmentation, it remains challenging to deploy the segmentation models to unseen domains due to domain biases. Domain adaptation can help in this regard by transferring knowledge…

Computer Vision and Pattern Recognition · Computer Science 2022-05-03 Binhui Xie , Mingjia Li , Shuang Li

Understanding protein sequences is vital and urgent for biology, healthcare, and medicine. Labeling approaches are expensive yet time-consuming, while the amount of unlabeled data is increasing quite faster than that of the labeled data due…

Computation and Language · Computer Science 2021-11-01 Liang He , Shizhuo Zhang , Lijun Wu , Huanhuan Xia , Fusong Ju , He Zhang , Siyuan Liu , Yingce Xia , Jianwei Zhu , Pan Deng , Bin Shao , Tao Qin , Tie-Yan Liu

Contrastive learning (CL) is a popular technique for self-supervised learning (SSL) of visual representations. It uses pairs of augmentations of unlabeled training examples to define a classification task for pretext learning of a deep…

Computer Vision and Pattern Recognition · Computer Science 2020-10-26 Chih-Hui Ho , Nuno Vasconcelos

Modern neural recording techniques such as two-photon imaging or Neuropixel probes allow to acquire vast time-series datasets with responses of hundreds or thousands of neurons. Contrastive learning is a powerful self-supervised framework…

Preserving maximal information is one of principles of designing self-supervised learning methodologies. To reach this goal, contrastive learning adopts an implicit way which is contrasting image pairs. However, we believe it is not fully…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Hong-Yu Zhou , Chixiang Lu , Sibei Yang , Xiaoguang Han , Yizhou Yu

Session-based recommendation, which aims to predict the next item of users' interest as per an existing sequence interaction of items, has attracted growing applications of Contrastive Learning (CL) with improved user and item…

Information Retrieval · Computer Science 2023-12-21 Zhengxiang Shi , Xi Wang , Aldo Lipani

We introduce a simple neural encoder architecture that can be trained using an unsupervised contrastive learning objective which gets its positive samples from data-augmented k-Nearest Neighbors search. We show that when built on top of…

Artificial Intelligence · Computer Science 2023-10-24 Robin Algayres , Adel Nabli , Benoit Sagot , Emmanuel Dupoux

T-cells play a key role in adaptive immunity by mounting specific responses against diverse pathogens. An effective binding between T-cell receptors (TCRs) and pathogen-derived peptides presented on Major Histocompatibility Complexes (MHCs)…

Quantitative Methods · Quantitative Biology 2025-09-05 Gian Marco Visani , Michael N. Pun , Anastasia A. Minervina , Philip Bradley , Paul Thomas , Armita Nourmohammad

Context-aware methods achieved great success in supervised scene text recognition via incorporating semantic priors from words. We argue that such prior contextual information can be interpreted as the relations of textual primitives due to…

Computer Vision and Pattern Recognition · Computer Science 2023-08-02 Jinglei Zhang , Tiancheng Lin , Yi Xu , Kai Chen , Rui Zhang

Pre-trained self-supervised models such as BERT have achieved striking success in learning sequence representations, especially for natural language processing. These models typically corrupt the given sequences with certain types of noise,…

Computation and Language · Computer Science 2020-11-02 Fuli Luo , Pengcheng Yang , Shicheng Li , Xuancheng Ren , Xu Sun

Self-Supervised Learning (SSL) enables us to pre-train foundation models without costly labeled data. Among SSL methods, Contrastive Learning (CL) methods are better at obtaining accurate semantic representations in noise interference.…

Image and Video Processing · Electrical Eng. & Systems 2026-02-06 Hengtong Shen , Haiyan Gu , Haitao Li , Yi Yang , Agen Qiu

Recently, self-supervised learning has attracted attention due to its remarkable ability to acquire meaningful representations for classification tasks without using semantic labels. This paper introduces a self-supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2022-02-09 Hyungtae Lee , Heesung Kwon

Contrastive learning (CL) has become a cornerstone of self-supervised pretraining (SSP) in foundation models, however, extending CL to pixel-wise representation, crucial for medical vision, remains an open problem. Standard CL formulates…

Computer Vision and Pattern Recognition · Computer Science 2025-06-27 Yuting He , Shuo Li

In natural language processing (NLP) of spoken languages, word embeddings have been shown to be a useful method to encode the meaning of words. Sign languages are visual languages, which require sign embeddings to capture the visual and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Ryan Wong , Necati Cihan Camgoz , Richard Bowden

An accurate binding affinity prediction between T-cell receptors and epitopes contributes decisively to develop successful immunotherapy strategies. Some state-of-the-art computational methods implement deep learning techniques by…

Machine Learning · Computer Science 2024-01-18 Etienne Goffinet , Raghvendra Mall , Ankita Singh , Rahul Kaushik , Filippo Castiglione

Semi-supervised action recognition aims to improve spatio-temporal reasoning ability with a few labeled data in conjunction with a large amount of unlabeled data. Albeit recent advancements, existing powerful methods are still prone to…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Yu Wang , Sanping Zhou , Kun Xia , Le Wang

Designing full-length, epitope-specific TCR {\alpha}\b{eta} remains challenging due to vast sequence space, data biases and incomplete modeling of immunogenetic constraints. We present LSMTCR, a scalable multi-architecture framework that…

Computational Engineering, Finance, and Science · Computer Science 2025-10-09 Ruihao Zhang , Xiao Liu

Self-supervised learning (SSL) methods such as masked language modeling have shown massive performance gains by pretraining transformer models for a variety of natural language processing tasks. The follow-up research adapted similar…

Computer Vision and Pattern Recognition · Computer Science 2022-05-12 Gokul Karthik Kumar , Sahal Shaji Mullappilly , Abhishek Singh Gehlot

Contrastive learning has been demonstrated to be effective in enhancing pre-trained language models (PLMs) to derive superior universal sentence embeddings. However, existing contrastive methods still have two limitations. Firstly, previous…

Computation and Language · Computer Science 2022-10-11 Yuxin Jiang , Linhan Zhang , Wei Wang

Contrastive learning is an approach to representation learning that utilizes naturally occurring similar and dissimilar pairs of data points to find useful embeddings of data. In the context of document classification under topic modeling…

Machine Learning · Computer Science 2020-03-05 Christopher Tosh , Akshay Krishnamurthy , Daniel Hsu