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Related papers: Tx-LLM: A Large Language Model for Therapeutics

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Mental health has attracted substantial attention in recent years and LLM can be an effective technology for alleviating this problem owing to its capability in text understanding and dialogue. However, existing research in this domain…

Computation and Language · Computer Science 2024-12-09 Jinpeng Hu , Tengteng Dong , Luo Gang , Hui Ma , Peng Zou , Xiao Sun , Dan Guo , Xun Yang , Meng Wang

Understanding molecules is key to understanding organisms and driving advances in drug discovery, requiring interdisciplinary knowledge across chemistry and biology. Although large molecular language models have achieved notable success in…

Machine Learning · Computer Science 2025-10-03 Dongki Kim , Wonbin Lee , Sung Ju Hwang

We present MeshLLM, a novel framework that leverages large language models (LLMs) to understand and generate text-serialized 3D meshes. Our approach addresses key limitations in existing methods, including the limited dataset scale when…

Developing artificial intelligence (AI) for clinical research requires a comprehensive data foundation that supports model training and rigorous evaluation. Here, we introduce TrialPanorama, a large-scale structured resource that aggregates…

Artificial Intelligence · Computer Science 2025-12-17 Zifeng Wang , Jiacheng Lin , Qiao Jin , Junyi Gao , Jathurshan Pradeepkumar , Pengcheng Jiang , Zhiyong Lu , Jimeng Sun

This paper provides a comprehensive survey of the latest research on multilingual large language models (MLLMs). MLLMs not only are able to understand and generate language across linguistic boundaries, but also represent an important…

Computation and Language · Computer Science 2024-11-20 Shaolin Zhu , Supryadi , Shaoyang Xu , Haoran Sun , Leiyu Pan , Menglong Cui , Jiangcun Du , Renren Jin , António Branco , Deyi Xiong

The deployment of large language models (LLMs) within the healthcare sector has sparked both enthusiasm and apprehension. These models exhibit the remarkable capability to provide proficient responses to free-text queries, demonstrating a…

Computation and Language · Computer Science 2024-07-09 Zabir Al Nazi , Wei Peng

The complexity and heterogeneity of data in many real-world applications pose significant challenges for traditional machine learning and signal processing techniques. For instance, in medicine, effective analysis of diverse physiological…

Machine Learning · Computer Science 2024-08-16 Nimeesha Chan , Felix Parker , William Bennett , Tianyi Wu , Mung Yao Jia , James Fackler , Kimia Ghobadi

Temporal Logic (TL) can be used to rigorously specify complex high-level specification for systems in many engineering applications. The translation between natural language (NL) and TL has been under-explored due to the lack of dataset and…

Computation and Language · Computer Science 2024-03-25 Yongchao Chen , Rujul Gandhi , Yang Zhang , Chuchu Fan

Large language models (LLMs) and their variants have shown extraordinary efficacy across numerous downstream natural language processing (NLP) tasks, which has presented a new vision for the development of NLP. Despite their remarkable…

Computation and Language · Computer Science 2024-01-18 Yazhou Zhang , Mengyao Wang , Youxi Wu , Prayag Tiwari , Qiuchi Li , Benyou Wang , Jing Qin

Large language models are being rapidly deployed across many fields such as healthcare, finance, transportation, and energy, where time-series data are fundamental components. The current works are still limited in their ability to perform…

Artificial Intelligence · Computer Science 2026-01-23 Paul Quinlan , Qingguo Li , Xiaodan Zhu

Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

Accurate molecular property prediction is a critical challenge with wide-ranging applications in chemistry, materials science, and drug discovery. Molecular representation methods, including fingerprints and graph neural networks (GNNs),…

Machine Learning · Computer Science 2025-08-13 Jiaxin Ju , Yizhen Zheng , Huan Yee Koh , Can Wang , Shirui Pan

In the molecular domain, numerous studies have explored the use of multimodal large language models (LLMs) to construct a general-purpose, multi-task molecular model. However, these efforts are still far from achieving a truly universal…

Machine Learning · Computer Science 2025-10-31 Chengxin Hu , Hao Li , Yihe Yuan , Zezheng Song , Chenyang Zhao , Haixin Wang

While Large Language Models (LLMs) have exhibited remarkable emergent capabilities through extensive pre-training, they still face critical limitations in generalizing to specialized domains and handling diverse linguistic variations, known…

Computation and Language · Computer Science 2025-05-28 Jinwu Hu , Zhitian Zhang , Guohao Chen , Xutao Wen , Chao Shuai , Wei Luo , Bin Xiao , Yuanqing Li , Mingkui Tan

Large Language Models (LLMs) represent a major step toward artificial general intelligence, significantly advancing our ability to interact with technology. While LLMs perform well on Natural Language Processing tasks -- such as…

Computation and Language · Computer Science 2025-05-15 Brandon Smith , Mohamed Reda Bouadjenek , Tahsin Alamgir Kheya , Phillip Dawson , Sunil Aryal

With extensive pre-trained knowledge and high-level general capabilities, large language models (LLMs) emerge as a promising avenue to augment reinforcement learning (RL) in aspects such as multi-task learning, sample efficiency, and…

Machine Learning · Computer Science 2024-11-21 Yuji Cao , Huan Zhao , Yuheng Cheng , Ting Shu , Yue Chen , Guolong Liu , Gaoqi Liang , Junhua Zhao , Jinyue Yan , Yun Li

There is widespread optimism that frontier Large Language Models (LLMs) and LLM-augmented systems have the potential to rapidly accelerate scientific discovery across disciplines. Today, many benchmarks exist to measure LLM knowledge and…

Despite the success of large language models (LLMs) on general-purpose tasks, their performance in highly specialized domains such as biomedicine remains unsatisfactory. A key limitation is the inability of LLMs to effectively leverage…

Computation and Language · Computer Science 2026-05-08 Xin Gao , Ruiyi Zhang , Meixi Du , Peijia Qin , Pengtao Xie

Large language models (LLMs) have demonstrated impressive capabilities in natural language understanding and generation, but the quality bar for medical and clinical applications is high. Today, attempts to assess models' clinical knowledge…

Large Vision-Language Models offer a new paradigm for AI-driven image understanding, enabling models to perform tasks without task-specific training. This flexibility holds particular promise across medicine, where expert-annotated data is…

Computer Vision and Pattern Recognition · Computer Science 2025-04-04 Anita Rau , Mark Endo , Josiah Aklilu , Jaewoo Heo , Khaled Saab , Alberto Paderno , Jeffrey Jopling , F. Christopher Holsinger , Serena Yeung-Levy