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We develop a new quantum neural network layer designed to run efficiently on a quantum computer but that can be simulated on a classical computer when restricted in the way it entangles input states. We first ask how a classical neural…

Quantum Physics · Physics 2020-11-26 Roberto Bondesan , Max Welling

Quantum machine learning has emerged as a promising application domain for near-term quantum hardware, particularly through hybrid quantum-classical models that leverage both classical and quantum processing. Although numerous hybrid…

Quantum Physics · Physics 2026-01-09 Dominik Freinberger , Philipp Moser

Quantum convolutional neural networks (QCNNs) offer a promising architecture for near-term quantum machine learning by combining hierarchical feature extraction with modest parameter growth. However, any QCNN operating on classical data…

Quantum Physics · Physics 2025-12-16 Xingyun Feng

Quantum Machine Learning continues to be a highly active area of interest within Quantum Computing. Many of these approaches have adapted classical approaches to the quantum settings, such as QuantumFlow, etc. We push forward this trend and…

Quantum Physics · Physics 2022-10-12 Samuel A. Stein , Ying Mao , James Ang , Ang Li

Structure-based virtual screening (SBVS) is a key computational strategy for identifying potential drug candidates by estimating the binding free energies (delta G_bind) of protein-ligand complexes. The immense size of chemical libraries,…

Quantum Physics · Physics 2025-07-15 Pei-Kun Yang

Many recent machine learning tasks resort to quantum computing to improve classification accuracy and training efficiency by taking advantage of quantum mechanics, known as quantum machine learning (QML). The variational quantum circuit…

Quantum Physics · Physics 2022-08-17 Jindi Wu , Zeyi Tao , Qun Li

We introduce a hybrid model combining a quantum-inspired tensor network and a variational quantum circuit to perform supervised learning tasks. This architecture allows for the classical and quantum parts of the model to be trained…

Quantum Physics · Physics 2021-10-13 Samuel Yen-Chi Chen , Chih-Min Huang , Chia-Wei Hsing , Ying-Jer Kao

As quantum machine-learning architectures mature, a central challenge is no longer their construction, but identifying the regimes in which they offer practical advantages over classical approaches. In this work, we introduce a framework…

Machine Learning · Computer Science 2026-01-21 Brandon B. Le , D. Keller

Image classification is a major application domain for conventional deep learning (DL). Quantum machine learning (QML) has the potential to revolutionize image classification. In any typical DL-based image classification, we use…

Computer Vision and Pattern Recognition · Computer Science 2021-09-21 Mahabubul Alam , Satwik Kundu , Rasit Onur Topaloglu , Swaroop Ghosh

Quantum neural network architectures that have little-to-no inductive biases are known to face trainability and generalization issues. Inspired by a similar problem, recent breakthroughs in machine learning address this challenge by…

Neural network (NN) potentials promise highly accurate molecular dynamics (MD) simulations within the computational complexity of classical MD force fields. However, when applied outside their training domain, NN potential predictions can…

Chemical Physics · Physics 2023-07-28 Stephan Thaler , Gregor Doehner , Julija Zavadlav

The development of quantum neural networks (QNNs) has attracted considerable attention due to their potential to surpass classical models in certain machine learning tasks. Nonetheless, it remains unclear under which conditions QNNs provide…

Quantum machine learning techniques have been proposed as a way to potentially enhance performance in machine learning applications. In this paper, we introduce two new quantum methods for neural networks. The first one is a quantum…

Inspired by the success of classical neural networks, there has been tremendous effort to develop classical effective neural networks into quantum concept. In this paper, a novel hybrid quantum-classical neural network with deep residual…

Machine Learning · Computer Science 2021-05-25 Yanying Liang , Wei Peng , Zhu-Jun Zheng , Olli Silvén , Guoying Zhao

Equivariant quantum neural networks (QNNs) are promising variational models that exploit symmetries to improve machine learning capabilities. Despite theoretical developments in equivariant QNNs, their implementation on near-term quantum…

Quantum Physics · Physics 2026-04-20 Koki Chinzei , Quoc Hoan Tran , Yasuhiro Endo , Hirotaka Oshima

We introduce and analyze a novel quantum machine learning model motivated by convolutional neural networks. Our quantum convolutional neural network (QCNN) makes use of only $O(\log(N))$ variational parameters for input sizes of $N$ qubits,…

Quantum Physics · Physics 2019-10-23 Iris Cong , Soonwon Choi , Mikhail D. Lukin

Continual learning aims to learn new tasks without forgetting previously learned ones. This is especially challenging when one cannot access data from previous tasks and when the model has a fixed capacity. Current regularization-based…

Machine Learning · Computer Science 2020-02-21 Sayna Ebrahimi , Mohamed Elhoseiny , Trevor Darrell , Marcus Rohrbach

Quantum machine learning aims to release the prowess of quantum computing to improve machine learning methods. By combining quantum computing methods with classical neural network techniques we aim to foster an increase of performance in…

High Energy Physics - Phenomenology · Physics 2021-03-17 Andrew Blance , Michael Spannowsky

Time series prediction is essential for human activities in diverse areas. A common approach to this task is to harness Recurrent Neural Networks (RNNs). However, while their predictions are quite accurate, their learning process is complex…

Quantum Physics · Physics 2025-05-30 Michał Siemaszko , Adam Buraczewski , Bertrand Le Saux , Magdalena Stobińska

Accurate and reliable diagnosis of diseases is crucial in enabling timely medical treatment and enhancing patient survival rates. In recent years, Machine Learning has revolutionized diagnostic practices by creating classification models…

Machine Learning · Computer Science 2025-12-02 Antonio Tudisco , Deborah Volpe , Giovanna Turvani