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The application of large language models (LLMs) in healthcare holds significant promise for enhancing clinical decision-making, medical research, and patient care. However, their integration into real-world clinical settings raises critical…

Computers and Society · Computer Science 2025-09-18 Manar Aljohani , Jun Hou , Sindhura Kommu , Xuan Wang

Trustworthiness in healthcare question-answering (QA) systems is important for ensuring patient safety, clinical effectiveness, and user confidence. As large language models (LLMs) become increasingly integrated into medical settings, the…

Computation and Language · Computer Science 2025-11-04 Yinuo Wang , Baiyang Wang , Robert E. Mercer , Frank Rudzicz , Sudipta Singha Roy , Pengjie Ren , Zhumin Chen , Xindi Wang

Large language models (LLMs) are increasingly deployed in medical contexts, raising critical concerns about safety, alignment, and susceptibility to adversarial manipulation. While prior benchmarks assess model refusal capabilities for…

Computation and Language · Computer Science 2025-05-19 Sijia Chen , Xiaomin Li , Mengxue Zhang , Eric Hanchen Jiang , Qingcheng Zeng , Chen-Hsiang Yu

With the advent of Large Language Models (LLMs), medical artificial intelligence (AI) has experienced substantial technological progress and paradigm shifts, highlighting the potential of LLMs to streamline healthcare delivery and improve…

Computation and Language · Computer Science 2024-12-10 Lei Liu , Xiaoyan Yang , Junchi Lei , Yue Shen , Jian Wang , Peng Wei , Zhixuan Chu , Zhan Qin , Kui Ren

The remarkable capabilities of Large Language Models (LLMs) make them increasingly compelling for adoption in real-world healthcare applications. However, the risks associated with using LLMs in medical applications have not been…

Integrating language models (LMs) in healthcare systems holds great promise for improving medical workflows and decision-making. However, a critical barrier to their real-world adoption is the lack of reliable evaluation of their…

Computation and Language · Computer Science 2025-12-15 Akash Ghosh , Srivarshinee Sridhar , Raghav Kaushik Ravi , Muhsin Muhsin , Sriparna Saha , Chirag Agarwal

Artificial Intelligence (AI) is revolutionizing scientific research, yet its growing integration into laboratory environments presents critical safety challenges. Large language models (LLMs) and vision language models (VLMs) now assist in…

Evaluating large language models (LLMs) in medicine is crucial because medical applications require high accuracy with little room for error. Current medical benchmarks have three main types: medical exam-based, comprehensive medical, and…

Large Language Models (LLMs) have exploded a new heatwave of AI for their ability to engage end-users in human-level conversations with detailed and articulate answers across many knowledge domains. In response to their fast adoption in…

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

Computation and Language · Computer Science 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

Large vision-language models (VLMs) commonly process images at native or high resolution to remain effective across tasks. This inflates visual tokens ofter to 97-99% of total tokens, resulting in high compute and latency, even when…

Computer Vision and Pattern Recognition · Computer Science 2026-03-23 Moshe Kimhi , Nimrod Shabtay , Raja Giryes , Chaim Baskin , Eli Schwartz

Large language models (LLMs) are approaching expert-level performance in medical question answering (QA), demonstrating strong potential to improve public healthcare. However, underlying biases related to sensitive attributes such as sex…

Artificial Intelligence · Computer Science 2026-01-13 Ying Xiao , Jie Huang , Ruijuan He , Jing Xiao , Mohammad Reza Mousavi , Yepang Liu , Kezhi Li , Zhenpeng Chen , Jie M. Zhang

Ensuring alignment, which refers to making models behave in accordance with human intentions [1,2], has become a critical task before deploying large language models (LLMs) in real-world applications. For instance, OpenAI devoted six months…

Artificial Intelligence · Computer Science 2024-03-22 Yang Liu , Yuanshun Yao , Jean-Francois Ton , Xiaoying Zhang , Ruocheng Guo , Hao Cheng , Yegor Klochkov , Muhammad Faaiz Taufiq , Hang Li

While Large Language Models (LLMs) demonstrate significant potential in providing accessible mental health support, their practical deployment raises critical trustworthiness concerns due to the domains high-stakes and safety-sensitive…

Computation and Language · Computer Science 2026-03-04 Zixin Xiong , Ziteng Wang , Haotian Fan , Xinjie Zhang , Wenxuan Wang

Recent advancements in multimodal large language models for video understanding (videoLLMs) have enhanced their capacity to process complex spatiotemporal data. However, challenges such as factual inaccuracies, harmful content, biases,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Youze Wang , Zijun Chen , Ruoyu Chen , Shishen Gu , Wenbo Hu , Jiayang Liu , Yinpeng Dong , Hang Su , Jun Zhu , Meng Wang , Richang Hong

Large-scale language models (LLMs) often offer clinical judgments based on incomplete information, increasing the risk of misdiagnosis. Existing studies have primarily evaluated confidence in single-turn, static settings, overlooking the…

Computation and Language · Computer Science 2026-01-23 Zhiyao Ren , Yibing Zhan , Siyuan Liang , Guozheng Ma , Baosheng Yu , Dacheng Tao

Recent advancements in large vision language models (VLMs) tailored for autonomous driving (AD) have shown strong scene understanding and reasoning capabilities, making them undeniable candidates for end-to-end driving systems. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-01-05 Shuo Xing , Hongyuan Hua , Xiangbo Gao , Shenzhe Zhu , Renjie Li , Kexin Tian , Xiaopeng Li , Heng Huang , Tianbao Yang , Zhangyang Wang , Yang Zhou , Huaxiu Yao , Zhengzhong Tu

The rapid progress of Large Models (LMs) has recently revolutionized various fields of deep learning with remarkable grades, ranging from Natural Language Processing (NLP) to Computer Vision (CV). However, LMs are increasingly challenged…

Computer Vision and Pattern Recognition · Computer Science 2024-02-02 Ziyan Guo , Li Xu , Jun Liu

Background: Clinical trials rely on transparent inclusion criteria to ensure generalizability. In contrast, benchmarks validating health-related large language models (LLMs) rarely characterize the "patient" or "query" populations they…

Artificial Intelligence · Computer Science 2026-04-17 Alvin Rajkomar , Pavan Sudarshan , Angela Lai , Lily Peng
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