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A central goal in systems biology and drug discovery is to predict the transcriptional response of cells to perturbations. This task is challenging due to the noisy and sparse nature of single-cell measurements, as well as the fact that…

Quantitative Methods · Quantitative Biology 2026-02-10 Chenglei Yu , Chuanrui Wang , Bangyan Liao , Tailin Wu

Multivariant time series (MTS) data are usually incomplete in real scenarios, and imputing the incomplete MTS is practically important to facilitate various time series mining tasks. Recently, diffusion model-based MTS imputation methods…

Machine Learning · Computer Science 2024-05-24 S. Zhang , S. Wang , H. Miao , H. Chen , C. Fan , J. Zhang

Diffusion models (DMs) excel in unconditional generation, as well as on applications such as image editing and restoration. The success of DMs lies in the iterative nature of diffusion: diffusion breaks down the complex process of mapping…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Beomsu Kim , Jaemin Kim , Jeongsol Kim , Jong Chul Ye

We adopt a Gamma and Malliavin Calculi point of view in order to generalize Score-based diffusion Generative Models (SGMs) to an infinite-dimensional abstract Hilbertian setting. Particularly, we define the forward noising process using…

Probability · Mathematics 2025-10-06 Giacomo Greco

Seismic imaging from sparsely acquired data faces challenges such as low image quality, discontinuities, and migration swing artifacts. Existing convolutional neural network (CNN)-based methods struggle with complex feature distributions…

Geophysics · Physics 2024-08-01 Xingchen Shi , Shijun Cheng , Weijian Mao , Wei Ouyang

Score-based diffusion models have emerged as one of the most promising frameworks for deep generative modelling. In this work we conduct a systematic comparison and theoretical analysis of different approaches to learning conditional…

Machine Learning · Computer Science 2021-11-29 Georgios Batzolis , Jan Stanczuk , Carola-Bibiane Schönlieb , Christian Etmann

Predicting counterfactual outcomes in longitudinal data, where sequential treatment decisions heavily depend on evolving patient states, is critical yet notoriously challenging due to complex time-dependent confounding and inadequate…

Machine Learning · Statistics 2026-04-15 Farbod Alinezhad , Jianfei Cao , Gary J. Young , Brady Post

Constrained clustering has gained significant attention in the field of machine learning as it can leverage prior information on a growing amount of only partially labeled data. Following recent advances in deep generative models, we…

Machine Learning · Computer Science 2022-02-02 Laura Manduchi , Kieran Chin-Cheong , Holger Michel , Sven Wellmann , Julia E. Vogt

Score-based Generative Models (SGMs) have achieved impressive performance in data generation across a wide range of applications and benefit from strong theoretical guarantees. Recently, methods inspired by statistical mechanics, in…

Classifier-free guidance (CFG) is the de facto standard for conditional sampling in diffusion models, yet it often reduces sample diversity. Using tools from statistical physics, we analyze the emergence of generative distortions induced by…

Machine Learning · Statistics 2026-05-11 Enrico Ventura , Beatrice Achilli , Luca Ambrogioni , Carlo Lucibello

Efficiently analyzing maps from upcoming large-scale surveys requires gaining direct access to a high-dimensional likelihood and generating large-scale fields with high fidelity, which both represent major challenges. Using CAMELS…

Cosmology and Nongalactic Astrophysics · Physics 2023-11-03 Sultan Hassan , Sambatra Andrianomena

We introduce a new type of graphical model called a "cumulative distribution network" (CDN), which expresses a joint cumulative distribution as a product of local functions. Each local function can be viewed as providing evidence about…

Machine Learning · Computer Science 2012-06-18 Jim Huang , Brendan J. Frey

While recent debiasing methods for Scene Graph Generation (SGG) have shown impressive performance, these efforts often attribute model bias solely to the long-tail distribution of relationships, overlooking the more profound causes stemming…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Li Liu , Shuzhou Sun , Shuaifeng Zhi , Fan Shi , Zhen Liu , Janne Heikkilä , Yongxiang Liu

Subspace clustering is a classical technique that has been widely used for human motion segmentation and other related tasks. However, existing segmentation methods often cluster data without guidance from prior knowledge, resulting in…

Computer Vision and Pattern Recognition · Computer Science 2022-02-11 Tao Zhou , Huazhu Fu , Chen Gong , Ling Shao , Fatih Porikli , Haibin Ling , Jianbing Shen

We investigate the utility of diffusion generative models to efficiently synthesise datasets that effectively train deep learning models for image analysis. Specifically, we propose novel $\Gamma$-distribution Latent Denoising Diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 David Stojanovski , Mariana da Silva , Pablo Lamata , Arian Beqiri , Alberto Gomez

Traditionally, chaotic systems are built on the domain of infinite precision in mathematics. However, the quantization is inevitable for any digital devices, which causes dynamical degradation. To cope with this problem, many methods were…

Chaotic Dynamics · Physics 2016-09-27 Qianxue Wang , Simin Yu , Chengqing Li , Jinhu Lü , Xiaole Fang , Christophe Guyeux , Jacques M. Bahi

In this paper, the problem of distributed caching in dense wireless small cell networks (SCNs) is studied using mean field games (MFGs). In the considered SCN, small base stations (SBSs) are equipped with data storage units and cooperate to…

Information Theory · Computer Science 2016-03-24 Kenza Hamidouche , Walid Saad , Mérouane Debbah , H. Vincent Poor

Multi-modal medical image completion has been extensively applied to alleviate the missing modality issue in a wealth of multi-modal diagnostic tasks. However, for most existing synthesis methods, their inferences of missing modalities can…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Xiangxi Meng , Yuning Gu , Yongsheng Pan , Nizhuan Wang , Peng Xue , Mengkang Lu , Xuming He , Yiqiang Zhan , Dinggang Shen

Score-based generative models (SGMs) have gained prominence in sparse-view CT reconstruction for their precise sampling of complex distributions. In SGM-based reconstruction, data consistency in the score-based diffusion model ensures close…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Weiwen Wu , Yanyang Wang

Score-based Generative Models (SGMs) is one leading method in generative modeling, renowned for their ability to generate high-quality samples from complex, high-dimensional data distributions. The method enjoys empirical success and is…

Machine Learning · Computer Science 2024-01-30 Sixu Li , Shi Chen , Qin Li