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Boron Neutron Capture Therapy (BNCT) is an innovative binary form of radiation therapy with high selectivity towards cancer tissue based on the neutron capture reaction 10B(n,$\alpha$)7Li, consisting in the exposition of patients to neutron…

Boron Neutron Capture Therapy (BNCT) is a neutron radiotherapy used to treat tumours cells previously doping with Boron-10. This therapy requires an epithermal neutron beam for the treatment of deep tumours and a thermal beam for shallow…

Instrumentation and Detectors · Physics 2021-06-02 M. Macías , B. Fernández , J. Praena

Selective accumulation of B-10 compound in tumour tissue is a fundamental condition for the achievement of BNCT (Boron Neutron Capture Therapy), since the effectiveness of therapy irradiation derives just from neutron capture reaction of…

Medical Physics · Physics 2007-12-05 M. Cortesi

Neutron computed tomography (nCT) is a 3D characterization technique used to image the internal morphology or chemical composition of samples in biology and materials sciences. A typical workflow involves placing the sample in the path of a…

Accurate dose calculation on cone beam computed tomography (CBCT) images is essential for modern proton treatment planning workflows, particularly when accounting for inter-fractional anatomical changes in adaptive treatment scenarios.…

Boron Neutron Capture Therapy (BNCT) is a form of radiotherapy based on the irradiation of the tumour with a low energy neutron beam, after the administration of a selective drug enriched in boron-10. The therapy exploits the high cross…

This study addresses the essential task of medical image segmentation, which involves the automatic identification and delineation of anatomical structures and pathological regions in medical images. Accurate segmentation is crucial in…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Seyedeh Sahar Taheri Otaghsara , Reza Rahmanzadeh

The superior soft tissue differentiation provided by MRI may enable more accurate tumor segmentation compared to CT and PET, potentially enhancing adaptive radiotherapy treatment planning. The Head and Neck Tumor Segmentation for MR-Guided…

Boron Neutron Capture Therapy (BNCT), is an advanced cancer therapy that destroys the cancer tumors using the well-known Li(p,n)Be . Because of the highly selectively reaction between a boron and a neutron, BNCT is effective for rapidly…

Accelerator Physics · Physics 2016-09-21 Zhu Xiaowen , Lu Yuanrong , Zhu Kun

Accurate brain tumor segmentation in the early stages of the disease is crucial for the treatment's effectiveness, avoiding exhaustive visual inspection of a qualified specialist on 3D MR brain images of multiple protocols (e.g., T1, T2,…

Image and Video Processing · Electrical Eng. & Systems 2024-02-09 Felipe C. R. Salvagnini , Gerson O. Barbosa , Alexandre X. Falcao , Cid A. N. Santos

Tumor segmentation in whole-body PET/CT imaging is crucial for precise disease evaluation and treatment planning. However, it remains challenging due to variability in lesion size, contrast, and anatomical distribution. Relying on manual…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Hussain Alasmawi

Dosimetry in BNCT poses significant challenges due to the indirect effect of neutrons interacting with elements within the body and uncertainties associated with the uptake of boron compounds used in clinical practice. Current treatment…

In this paper, we present a fully automatic brain tumor segmentation method based on Deep Neural Networks (DNNs). The proposed networks are tailored to glioblastomas (both low and high grade) pictured in MR images. By their very nature,…

Computer Vision and Pattern Recognition · Computer Science 2016-05-23 Mohammad Havaei , Axel Davy , David Warde-Farley , Antoine Biard , Aaron Courville , Yoshua Bengio , Chris Pal , Pierre-Marc Jodoin , Hugo Larochelle

The accurate imaging and quantitative measurement of 478-keV prompt gamma rays are critical for advancing boron neutron capture therapy (BNCT), a promising cancer treatment. Although numerical simulations have indicated that such…

Instrumentation and Detectors · Physics 2025-09-03 Tetsuya Mizumoto , Shotaro Komura , Atsushi Takada , Yoshinori Sakurai , Toru Tanimori

A major challenge in brain tumor treatment planning and quantitative evaluation is determination of the tumor extent. The noninvasive magnetic resonance imaging (MRI) technique has emerged as a front-line diagnostic tool for brain tumors…

Computer Vision and Pattern Recognition · Computer Science 2017-06-06 Hao Dong , Guang Yang , Fangde Liu , Yuanhan Mo , Yike Guo

Radiotherapy is the main treatment modality for nasopharynx cancer. Delineation of Gross Target Volume (GTV) from medical images such as CT and MRI images is a prerequisite for radiotherapy. As manual delineation is time-consuming and…

Image and Video Processing · Electrical Eng. & Systems 2021-01-28 Haochen Mei , Wenhui Lei , Ran Gu , Shan Ye , Zhengwentai Sun , Shichuan Zhang , Guotai Wang

We apply an ensemble of modified TransBTS, nnU-Net, and a combination of both for the segmentation task of the BraTS 2021 challenge. In fact, we change the original architecture of the TransBTS model by adding Squeeze-and-Excitation blocks,…

Image and Video Processing · Electrical Eng. & Systems 2021-10-18 Mariia Dobko , Danylo-Ivan Kolinko , Ostap Viniavskyi , Yurii Yelisieiev

Brain tumor segmentation plays a crucial role in computer-aided diagnosis. This study introduces a novel segmentation algorithm utilizing a modified nnU-Net architecture. Within the nnU-Net architecture's encoder section, we enhance…

Image and Video Processing · Electrical Eng. & Systems 2024-09-23 Sahaj K. Mistry , Sourav Saini , Aashray Gupta , Aayush Gupta , Sunny Rai , Vinit Jakhetiya , Ujjwal Baid , Sharath Chandra Guntuku

Convolutional neural networks have achieved excellent results in automatic medical image segmentation. In this study, we proposed a novel 3D multi-path DenseNet for generating the accurate glioblastoma (GBM) tumor contour from four…

Medical Physics · Physics 2021-02-25 Jie Fu , Kamal Singhrao , X. Sharon Qi , Yingli Yang , Dan Ruan , John H. Lewis

Purpose: Accurate segmentation of clinical target volumes (CTV) and organs-at-risk is crucial for optimizing gynecologic brachytherapy (GYN-BT) treatment planning. However, anatomical variability, low soft-tissue contrast in CT imaging, and…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Mingzhe Hu , Yuan Gao , Yuheng Li , Ricahrd LJ Qiu , Chih-Wei Chang , Keyur D. Shah , Priyanka Kapoor , Beth Bradshaw , Yuan Shao , Justin Roper , Jill Remick , Zhen Tian , Xiaofeng Yang
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