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We propose ProtLLM, a versatile cross-modal large language model (LLM) for both protein-centric and protein-language tasks. ProtLLM features a unique dynamic protein mounting mechanism, enabling it to handle complex inputs where the natural…

Biomolecules · Quantitative Biology 2024-03-14 Le Zhuo , Zewen Chi , Minghao Xu , Heyan Huang , Heqi Zheng , Conghui He , Xian-Ling Mao , Wentao Zhang

Neural language models are black-boxes--both linguistic patterns and factual knowledge are distributed across billions of opaque parameters. This entangled encoding makes it difficult to reliably inspect, verify, or update specific facts.…

Recent advancements in recommendation systems have shifted towards more comprehensive and personalized recommendations by utilizing large language models (LLM). However, effectively integrating LLM's commonsense knowledge and reasoning…

Information Retrieval · Computer Science 2023-08-22 Zhixuan Chu , Hongyan Hao , Xin Ouyang , Simeng Wang , Yan Wang , Yue Shen , Jinjie Gu , Qing Cui , Longfei Li , Siqiao Xue , James Y Zhang , Sheng Li

The exponential growth of text-based data in domains such as healthcare, education, and social sciences has outpaced the capacity of traditional qualitative analysis methods, which are time-intensive and prone to subjectivity. Large…

Travel behavior prediction is a core problem in transportation demand management and is traditionally addressed using numerical models calibrated on observed data. With recent advances in large language models (LLMs), new opportunities have…

Machine Learning · Computer Science 2026-03-12 Baichuan Mo , Hanyong Xu , Ruoyun Ma , Jung-Hoon Cho , Dingyi Zhuang , Xiaotong Guo , Jinhua Zhao

Concepts play a pivotal role in various human cognitive functions, including learning, reasoning and communication. However, there is very little work on endowing machines with the ability to form and reason with concepts. In particular,…

Computation and Language · Computer Science 2023-11-06 Chen Shani , Jilles Vreeken , Dafna Shahaf

Piaget's Theory of Cognitive Development (PTC) posits that the development of cognitive levels forms the foundation for human learning across various abilities. As Large Language Models (LLMs) have recently shown remarkable abilities across…

Computation and Language · Computer Science 2025-02-13 Xinglin Wang , Peiwen Yuan , Shaoxiong Feng , Yiwei Li , Boyuan Pan , Heda Wang , Yao Hu , Kan Li

Following the recent popularity of Large Language Models (LLMs), several attempts have been made to extend them to the visual domain. From having a visual assistant that could guide us through unfamiliar environments to generative models…

Despite the impressive performance of Large Language Models (LLM) for various natural language processing tasks, little is known about their comprehension of geographic data and related ability to facilitate informed geospatial…

Computation and Language · Computer Science 2023-10-23 Prabin Bhandari , Antonios Anastasopoulos , Dieter Pfoser

Competency modeling is widely used in human resource management to select, develop, and evaluate talent. However, traditional expert-driven approaches rely heavily on manual analysis of large volumes of interview transcripts, making them…

Computation and Language · Computer Science 2026-02-16 Silin Du , Manqing Xin , Raymond Jia Wang

Tool learning has emerged as a promising direction by extending Large Language Models' (LLMs) capabilities with external tools. Existing tool learning studies primarily focus on the general-purpose tool-use capability, which addresses…

Computation and Language · Computer Science 2025-02-27 Qiancheng Xu , Yongqi Li , Heming Xia , Fan Liu , Min Yang , Wenjie Li

The causal capabilities of large language models (LLMs) are a matter of significant debate, with critical implications for the use of LLMs in societally impactful domains such as medicine, science, law, and policy. We conduct a "behavorial"…

Artificial Intelligence · Computer Science 2024-08-21 Emre Kıcıman , Robert Ness , Amit Sharma , Chenhao Tan

In the past five years, research has shifted from traditional Machine Learning (ML) and Deep Learning (DL) approaches to leveraging Large Language Models (LLMs) , including multimodality, for data augmentation to enhance generalization, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Ranjan Sapkota , Shaina Raza , Maged Shoman , Achyut Paudel , Manoj Karkee

Large-scale task planning is a major challenge. Recent work exploits large language models (LLMs) directly as a policy and shows surprisingly interesting results. This paper shows that LLMs provide a commonsense model of the world in…

Robotics · Computer Science 2023-10-31 Zirui Zhao , Wee Sun Lee , David Hsu

Geolocation is now a vital aspect of modern life, offering numerous benefits but also presenting serious privacy concerns. The advent of large vision-language models (LVLMs) with advanced image-processing capabilities introduces new risks,…

Cryptography and Security · Computer Science 2024-08-20 Yi Liu , Junchen Ding , Gelei Deng , Yuekang Li , Tianwei Zhang , Weisong Sun , Yaowen Zheng , Jingquan Ge , Yang Liu

The effective assessment of the instruction-following ability of large language models (LLMs) is of paramount importance. A model that cannot adhere to human instructions might be not able to provide reliable and helpful responses. In…

Computation and Language · Computer Science 2023-11-17 Yimin Jing , Renren Jin , Jiahao Hu , Huishi Qiu , Xiaohua Wang , Peng Wang , Deyi Xiong

Large language models (LLMs) are increasingly used in high-stakes settings, where overconfident responses can mislead users. Reliable confidence estimation has been shown to enhance trust and task accuracy. Yet existing methods face…

Computation and Language · Computer Science 2025-09-30 Linwei Tao , Yi-Fan Yeh , Bo Kai , Minjing Dong , Tao Huang , Tom A. Lamb , Jialin Yu , Philip H. S. Torr , Chang Xu

Large language models have made significant progress in the past few years. However, they are either generic {\it or} field specific, splitting the community into different groups. In this paper, we unify these large language models into a…

Computer Vision and Pattern Recognition · Computer Science 2023-07-26 Yuanhao Gong

The advancement of Large Language Models (LLMs), including GPT-4, provides exciting new opportunities for generative design. We investigate the application of this tool across the entire design and manufacturing workflow. Specifically, we…

Location-based services play an critical role in improving the quality of our daily lives. Despite the proliferation of numerous specialized AI models within spatio-temporal context of location-based services, these models struggle to…

Machine Learning · Computer Science 2024-06-19 Yue Jiang , Qin Chao , Yile Chen , Xiucheng Li , Shuai Liu , Gao Cong