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By coupling peptides with DNA tags (i.e., 'barcodes'), it is now possible to harness high-throughput sequencing (HTS) technologies to enable highly multiplexed peptide-based assays, which have a variety of potential applications including…

Quantitative Methods · Quantitative Biology 2020-07-13 Zane W. Fink , Vidal Martinez , John Altin , Jason T. Ladner

The installation and maintenance of scientific software for research in experimental, phenomenological, and theoretical High Energy Physics (HEP) requires a considerable amount of time and expertise. While many tools are available to make…

Computational Physics · Physics 2023-03-01 Thomas Hahn , Andrii Verbytskyi

Beyond the conventional trial-and-error method, machine learning offers a great opportunity to accelerate the discovery of functional materials, but still often suffers from difficulties such as limited materials data and unbalanced…

Materials Science · Physics 2021-08-23 Xing-Yu Ma , Hou-Yi Lyu , Kuan-Rong Hao , Zhen-Gang Zhu , Qing-Bo Yan , Gang Su

Accelerating the discovery of structural materials is essential for applications in hard and refractory alloys, hypersonic platforms, nuclear systems, and other extreme environment technologies. Progress is often constrained by slow…

Materials Science · Physics 2025-12-16 Vivek Chawla , Dayakar Penumadu , Sergei Kalinin

Among the upgrades in current high energy physics (HEP) experiments and the new facilities coming online, solving software challenges has become integral for the success of the collaborations, The demand for human resources highly-skilled…

Physics Education · Physics 2023-03-01 Michel H. Villanueva , Sudhir Malik , Meirin Oan Evans

Pythonic Black-box Electronic Structure Tool (PyBEST) represents a fully-fledged modern electronic structure software package developed at Nicolaus Copernicus University in Toru\'n. The package provides an efficient and reliable platform…

Computational acceleration of performance-metric-based materials discovery via high-throughput screening and machine learning methods is becoming widespread. Nevertheless, development and optimization of the opto-electronic properties that…

Materials Science · Physics 2019-06-10 Jonathon N. Baker , Preston C. Bowes , Joshua S. Harris , Douglas L. Irving

The practically unlimited high-dimensional composition space of high-entropy materials (HEMs) has emerged as an exciting platform for functional materials design and discovery. However, the identification of stable and synthesizable HEMs…

Materials Science · Physics 2024-03-01 Dibyendu Dey , Liangbo Liang , Liping Yu

With the advancement of the Materials Genome Initiative, high-throughput computation has become central to accelerating materials discovery. However, conventional first-principles workflows are cumbersome and error-prone. Existing…

Materials Science · Physics 2026-04-08 Lianduan Zeng , Xiao Zhou , Xueru Zheng , Ning Gao , Lei Liu , Yunxuan Cao , Hongjian Chen , Zhongyang Wang , Tongxiang Fan

High Energy Physics (HEP) experiments are making increasing use of GPUs and GPU dominated High Performance Computer facilities. Both the software and hardware of these systems are rapidly evolving, creating challenges for experiments to…

High Energy Physics - Experiment · Physics 2025-05-15 Mohammad Atif , Pengfei Ding , Ka Hei Martin Kwok , Charles Leggett

Conventionally, high-throughput computational materials searches start from an input set of bulk compounds extracted from material databases, and this set is screened for candidate materials for specific applications. In contrast, many…

Materials Science · Physics 2023-04-11 Rachel Woods-Robinson , Matthew K. Horton , Kristin A. Persson

Predicting material properties of disordered systems remains a long-standing and formidable challenge in rational materials design. To address this issue, we introduce an automated software framework capable of modeling partial occupation…

Materials Science · Physics 2015-11-16 Keson Yang , Corey Oses , Stefano Curtarolo

New facilities of the 2020s, such as the High Luminosity Large Hadron Collider (HL-LHC), will be relevant through at least the 2030s. This means that their software efforts and those that are used to analyze their data need to consider…

Context: Software startups develop innovative, software-intensive products. Given the uncertainty associated with such an innovative context, experimentation is a valuable approach for these companies, especially in the early stages of the…

Computers and Society · Computer Science 2022-01-11 Jorge Melegati , Eduardo Guerra , Xiaofeng Wang

The high computational cost of ab-initio methods limits their application in predicting electronic properties at the device scale. Therefore, an efficient method is needed to map the atomic structure to the electronic structure quickly.…

Materials Science · Physics 2025-09-09 Yunlong Wang , Zhixin Liang , Chi Ding , Junjie Wang , Zheyong Fan , Hui-Tian Wang , Dingyu Xing , Jian Sun

Machine- and deep-learning approaches for biological sequences depend critically on transforming raw DNA, RNA, and protein FASTA files into informative numerical representations. However, this process is often fragmented across multiple…

Genomics · Quantitative Biology 2025-12-01 Hamid Ismail , Marwan Bikdash

As the proliferation of high-throughput approaches in materials science is increasing the wealth of data in the field, the gap between accumulated-information and derived-knowledge widens. We address the issue of scientific discovery in…

Objective: Medical relations are the core components of medical knowledge graphs that are needed for healthcare artificial intelligence. However, the requirement of expert annotation by conventional algorithm development processes creates a…

Machine Learning · Computer Science 2020-09-09 Yucong Lin , Keming Lu , Yulin Chen , Chuan Hong , Sheng Yu

High-entropy alloys, which exist in the high-dimensional composition space, provide enormous unique opportunities for realizing unprecedented structural and functional properties. A fundamental challenge, however, lies in how to predict the…

Materials Science · Physics 2021-05-20 Jie Qi , Andrew M. Cheung , S. Joseph Poon

We propose an efficient computational methodology for predicting the synthesizability of high entropy oxides (HEOs) in a large space of possible candidate compounds. HEOs are a growing field with an enormous potential chemical composition…

Materials Science · Physics 2026-03-03 Oliver A. Dicks , Solveig S. Aamlid , Alannah M. Hallas , Joerg Rottler
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