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In this paper, we propose a realistic mathematical model taking into account the mutual interference among the interacting populations. This model attempts to describe the control (vaccination) function as a function of the number of…

Neural and Evolutionary Computing · Computer Science 2016-11-18 V. Sree Hari Rao , M. Naresh Kumar

One of the major issues in the theoretical modeling of epidemic spreading is the development of methods to control the transmission of an infectious agent. Human behavior plays a fundamental role in the spreading dynamics and can be used to…

I study the spreading of infectious diseases on heterogeneous populations. I represent the population structure by a contact-graph where vertices represent agents and edges represent disease transmission channels among them. The population…

Populations and Evolution · Quantitative Biology 2009-11-13 Alexei Vazquez

Infectious diseases, either emerging or long-lasting, place numerous people at risk and bring heavy public health burdens worldwide. In the process against infectious diseases, predicting the epidemic risk by modeling the disease…

Machine Learning · Computer Science 2023-08-08 Mutong Liu , Yang Liu , Jiming Liu

In response to the ongoing pandemic and health emergency of COVID-19, several models have been used to understand the dynamics of virus spread. Some employ mathematical models like the compartmental SEIHRD approach and others rely on…

Computational Geometry · Computer Science 2024-09-10 Raunak Sarbajna , Karima Elgarroussi , Hoang D Vo , Jianyuan Ni , Christoph F. Eick

The Agent Based Model community has a rich and diverse ecosystem of libraries, platforms, and applications to help modelers develop rigorous simulations. Despite this robust and diverse ecosystem, the complexity of life from microbial…

Computers and Society · Computer Science 2021-11-16 Thomas Pike , Samantha Golden , Daniel Lowdermilk , Brandon Luong , Benjamin Rosado

The vision of personalized medicine is to identify interventions that maintain or restore a person's health based on their individual biology. Medical digital twins, computational models that integrate a wide range of health-related data…

Quantitative Methods · Quantitative Biology 2025-10-21 Luis L. Fonseca , Lucas Böttcher , Borna Mehrad , Reinhard C. Laubenbacher

Forecasts of the trajectory of an infectious agent can help guide public health decision making. A traditional approach to forecasting fits a computational model to structured data and generates a predictive distribution. However, human…

Metapopulation epidemic models help capture the spatial dimension of infectious disease spread by dividing heterogeneous populations into separate but interconnected communities, represented by nodes in a network. In the event of an…

Populations and Evolution · Quantitative Biology 2025-02-21 Henrik Zunker , Philipp Dönges , Patrick Lenz , Seba Contreras , Martin J. Kühn

Effective pandemic control requires timely and coordinated policymaking across administrative regions that are intrinsically interdependent. However, human-driven responses are often fragmented and reactive, with policies formulated in…

Artificial Intelligence · Computer Science 2026-01-15 Ziyi Shi , Xusen Guo , Hongliang Lu , Mingxing Peng , Haotian Wang , Zheng Zhu , Zhenning Li , Yuxuan Liang , Xinhu Zheng , Hai Yang

In the present paper, our goal is to establish a framework for the mathematical modelling and the analysis of the spread of an epidemic in a large population commuting regularly, typically along a time-periodic pattern, as is roughly…

Populations and Evolution · Quantitative Biology 2024-08-29 Pierre-Alexandre Bliman , Boureima Sangaré , Assane Savadogo

Agent-Based Models (ABMs) are powerful tools for studying emergent properties in complex systems. In ABMs, agent behaviors are governed by local interactions and stochastic rules. However, these rules are, in general, non-differentiable,…

Artificial Intelligence · Computer Science 2025-11-27 Francesco Cozzi , Marco Pangallo , Alan Perotti , André Panisson , Corrado Monti

The study of infectious disease propagation is essential for understanding and controlling epidemics. One of the most useful tools for gaining insights into the spread of infectious diseases is mathematical modelling. In terms of…

The duration, type and structure of connections between individuals in real-world populations play a crucial role in how diseases invade and spread. Here, we incorporate the aforementioned heterogeneities into a model by considering a…

Physics and Society · Physics 2018-04-05 Rosanna C Barnard , Istvan Z Kiss , Luc Berthouze , Joel C Miller

Antimicrobial peptides (AMPs) play important roles in cancer, autoimmune diseases, and aging. A critical aspect of AMP functionality is their targeted interaction with pathogen membranes, which often possess altered lipid compositions.…

Computer simulations offer a robust toolset for exploring complex systems across various disciplines. A particularly impactful approach within this realm is Agent-Based Modeling (ABM), which harnesses the interactions of individual agents…

Artificial Intelligence · Computer Science 2023-12-19 Zengqing Wu , Run Peng , Xu Han , Shuyuan Zheng , Yixin Zhang , Chuan Xiao

Epidemiological forecasting from surveillance data is a hard problem and hybridizing mechanistic compartmental models with neural models is a natural direction. The mechanistic structure helps keep trajectories epidemiologically plausible,…

Machine Learning · Computer Science 2026-02-09 Yiqi Su , Ray Lee , Jiaming Cui , Naren Ramakrishnan

Recent statistics of malaria shows that over 200 million cases and estimated deaths of nearly half a million occur globally. Africa alone accounts for almost 90% of the cases. Several studies have been conducted to understand the disease…

Populations and Evolution · Quantitative Biology 2020-04-15 Babagana Modu , Nereida Polovina , Savas Konur

Agent Based Modelling (ABM) is a computational framework for simulating the behaviours and interactions of autonomous agents. As Agent Based Models are usually representative of complex systems, obtaining a likelihood function of the model…

Artificial Intelligence · Computer Science 2021-07-09 D. Townsend

An agent-based model of population dynamics is presented. The model has as its expected behaviour the population dynamics of the equation-based Webworld model, within which large communities of species can be grown on evolutionary time…

Populations and Evolution · Quantitative Biology 2008-11-18 Craig R. Powell