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Inverse protein folding generates valid amino acid sequences that can fold into a desired protein structure, with recent deep-learning advances showing strong potential and competitive performance. However, challenges remain, such as…

Biomolecules · Quantitative Biology 2025-07-29 Peizhen Bai , Filip Miljković , Xianyuan Liu , Leonardo De Maria , Rebecca Croasdale-Wood , Owen Rackham , Haiping Lu

The emergence of generative AI and controllable diffusion has made image-to-image synthesis increasingly practical and efficient. However, when input images exhibit low entropy and sparse, the inherent characteristics of diffusion models…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Hao Wang , Xiwen Chen , Ashish Bastola , Jiayou Qin , Abolfazl Razi

Diffusion models have become increasingly popular for generative modeling due to their ability to generate high-quality samples. This has unlocked exciting new possibilities for solving inverse problems, especially in image restoration and…

Recent studies have shown that diffusion language models achieve remarkable data efficiency under limited-data constraints, yet the underlying mechanisms remain unclear. In this work, we perform extensive ablation experiments to disentangle…

Computation and Language · Computer Science 2025-10-07 Zitian Gao , Haoming Luo , Lynx Chen , Jason Klein Liu , Ran Tao , Joey Zhou , Bryan Dai

Diffusion models have gained tremendous success in text-to-image generation, yet still lag behind with visual understanding tasks, an area dominated by autoregressive vision-language models. We propose a large-scale and fully end-to-end…

Computer Vision and Pattern Recognition · Computer Science 2025-04-03 Zijie Li , Henry Li , Yichun Shi , Amir Barati Farimani , Yuval Kluger , Linjie Yang , Peng Wang

Diffusion Language Models (DLMs) are rapidly emerging as a powerful and promising alternative to the dominant autoregressive (AR) paradigm. By generating tokens in parallel through an iterative denoising process, DLMs possess inherent…

Computation and Language · Computer Science 2025-12-08 Tianyi Li , Mingda Chen , Bowei Guo , Zhiqiang Shen

The tremendous progress in neural image generation, coupled with the emergence of seemingly omnipotent vision-language models has finally enabled text-based interfaces for creating and editing images. Handling generic images requires a…

Computer Vision and Pattern Recognition · Computer Science 2023-07-27 Omri Avrahami , Ohad Fried , Dani Lischinski

Denoising diffusion probabilistic models are currently becoming the leading paradigm of generative modeling for many important data modalities. Being the most prevalent in the computer vision community, diffusion models have also recently…

Machine Learning · Computer Science 2024-10-08 Akim Kotelnikov , Dmitry Baranchuk , Ivan Rubachev , Artem Babenko

While continuous diffusion models have achieved remarkable success, discrete diffusion offers a unified framework for jointly modeling text and images. Beyond unification, discrete diffusion provides faster inference, finer control, and…

This paper presents a novel theoretical framework for understanding how diffusion models can learn disentangled representations. Within this framework, we establish identifiability conditions for general disentangled latent variable models,…

World models that forecast environmental changes from actions are vital for autonomous driving models with strong generalization. The prevailing driving world model mainly build on video prediction model. Although these models can produce…

Computer Vision and Pattern Recognition · Computer Science 2025-02-18 Jingcheng Ni , Yuxin Guo , Yichen Liu , Rui Chen , Lewei Lu , Zehuan Wu

Discrete diffusion models, like continuous diffusion models, generate high-quality samples by gradually undoing noise applied to datapoints with a Markov process. Gradual generation in theory comes with many conceptual benefits; for…

Machine Learning · Computer Science 2025-09-30 Alan N. Amin , Nate Gruver , Andrew Gordon Wilson

Foundation models, particularly Large Language Models (LLMs), have revolutionized text and video processing, yet time series data presents distinct challenges for such approaches due to domain-specific features such as missing values,…

Machine Learning · Computer Science 2025-02-12 Defu Cao , Wen Ye , Yizhou Zhang , Yan Liu

Masked autoencoding has achieved great success for self-supervised learning in the image and language domains. However, mask based pretraining has yet to show benefits for point cloud understanding, likely due to standard backbones like…

Computer Vision and Pattern Recognition · Computer Science 2022-08-02 Haotian Liu , Mu Cai , Yong Jae Lee

There has been a lot of recent interest in designing neural network models to estimate a distribution from a set of examples. We introduce a simple modification for autoencoder neural networks that yields powerful generative models. Our…

Machine Learning · Computer Science 2015-06-08 Mathieu Germain , Karol Gregor , Iain Murray , Hugo Larochelle

Diffusion models have established themselves as state-of-the-art generative models across various data modalities, including images and videos, due to their ability to accurately approximate complex data distributions. Unlike traditional…

Machine Learning · Computer Science 2025-10-23 Daniel Wesego

Domain generalization (DG) for object detection aims to enhance detectors' performance in unseen scenarios. This task remains challenging due to complex variations in real-world applications. Recently, diffusion models have demonstrated…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Boyong He , Yuxiang Ji , Qianwen Ye , Zhuoyue Tan , Liaoni Wu

Masked diffusion models (MDM) exhibit superior generalization when learned using a Partial masking scheme (Prime). This approach converts tokens into sub-tokens and models the diffusion process at the sub-token level. We identify two…

Machine Learning · Computer Science 2026-05-22 Chen-Hao Chao , Wei-Fang Sun , Junwei Quan , Chun-Yi Lee , Rahul G. Krishnan

Discrete diffusion models have recently shown great promise for modeling complex discrete data, with masked diffusion models (MDMs) offering a compelling trade-off between quality and generation speed. MDMs denoise by progressively…

Machine Learning · Computer Science 2026-04-15 Tianyu Xie , Shuchen Xue , Zijin Feng , Tianyang Hu , Jiacheng Sun , Zhenguo Li , Cheng Zhang

Despite the rapid advancement of unsupervised learning in visual representation, it requires training on large-scale datasets that demand costly data collection, and pose additional challenges due to concerns regarding data privacy.…

Computer Vision and Pattern Recognition · Computer Science 2023-08-15 David Junhao Zhang , Mutian Xu , Chuhui Xue , Wenqing Zhang , Xiaoguang Han , Song Bai , Mike Zheng Shou
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