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Meta-analysis is a powerful tool to synthesize findings from multiple studies. The normal-normal random-effects model is widely used to account for between-study heterogeneity. However, meta-analysis of sparse data, which may arise when the…
In meta-analysis of diagnostic test accuracy, summary receiver operating characteristic (SROC) is a recommended method to summarize the discriminant capacity of a diagnostic test in the presence of study-specific cutoff values and the area…
In meta-analyses, publication bias is a well-known, important and challenging issue because the validity of the results from a meta-analysis is threatened if the sample of studies retrieved for review is biased. One popular method to deal…
Prospective registration of study protocols in clinical trial registries is a useful way to minimize the risk of publication bias in meta-analysis, and several clinical trial registries are available nowadays. However, they are mainly used…
In systematic reviews and meta-analyses, publication bias (PB) is one of the serious concerns and mainly induced by selective publication of academic literatures. Although many methods have been proposed to deal with PB, almost all the…
Publication bias is a major concern in conducting systematic reviews and meta-analyses. Various sensitivity analysis or bias-correction methods have been developed based on selection models and they have some advantages over the widely used…
The validity of conclusions from meta-analysis is potentially threatened by publication bias. Most existing procedures for correcting publication bias assume normality of the study-specific effects that account for between-study…
In the analysis of prognosis studies with time-to-event outcomes, dichotomization of patients is often made. As the evaluations of prognostic capacity, the survivals of groups with high/low expression of the biomarker are often estimated by…
Publication bias (PB) is one of the most vital threats to the accuracy of meta-analysis. Adjustment or sensitivity analysis based on selection models, which describe the probability of a study being published, provide a more objective…
Meta analysis is commonly-used to synthesize multiple results from individual studies. However, its validation is usually threatened by publication bias and between-study heterogeneity, which can be captured by the Copas selection model.…
Multivariate meta-analysis of test accuracy studies when tests are evaluated in terms of sensitivity and specificity at more than one threshold represents an effective way to synthesize results by fully exploiting the data, if compared to…
Abstract Publication bias has been a problem facing meta-analysts. Methods adjusting for publication bias have been proposed in the literature. Comparative studies for methods adjusting for publication bias are found in the literature, but…
Network meta-analysis (NMA) is a useful tool to compare multiple interventions simultaneously in a single meta-analysis, it can be very helpful for medical decision making when the study aims to find the best therapy among several active…
The summary receiver operating characteristic (SROC) curve has been recommended as one important meta-analytical summary to represent the accuracy of a diagnostic test in the presence of heterogeneous cutoff values. However, selective…
The present study investigates the performance of several statistical tests to detect publication bias in diagnostic meta-analysis by means of simulation. While bivariate models should be used to pool data from primary studies in diagnostic…
The current statistical procedures implemented in statistical software packages for pooling of diagnostic test accuracy data include hSROC regression and the bivariate random-effects meta-analysis model (BRMA). However, these models do not…
Systematic reviews aim to summarize all the available evidence relevant to a particular research question. If appropriate, the data from identified studies are quantitatively combined in a meta-analysis. Often only few studies regarding a…
Meta-analysis of diagnostic test accuracy (DTA) is the powerful statistical method for synthesizing and evaluating the diagnostic capacity of the medical tests and has been extensively used by clinical physicians and healthcare…
Copas' method corrects a pooled estimate from an aggregated data meta-analysis for publication bias. Its performance has been studied for one particular mechanism of publication bias. We show through simulations that Copas' method is not…
Publication bias undermines meta-analytic inference, yet visual diagnostics for detecting model misfit due to publication bias are lacking. We propose the z-curve plot, a publication-bias-focused absolute model fit diagnostic. The z-curve…