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Non-invasive measurement of the arterial blood speed gives rise to important healthinformation such as cardio output and blood supplies to vital organs. The magnitude andchange in arterial blood speed are key indicators of the health…

Medical Physics · Physics 2021-10-22 Alex Ce Zhang , Yu-Hwa Lo

Functionally significant coronary artery disease (CAD) is caused by plaque buildup in the coronary arteries, potentially leading to narrowing of the arterial lumen, i.e. coronary stenosis, that significantly obstructs blood flow to the…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Nils Hampe , Sanne G. M. van Velzen , Jean-Paul Aben , Carlos Collet , Ivana Išgum

Coronary Artery Disease (CAD) results from plaque deposit in a coronary artery. Early diagnosis is imperative, so a non-invasive detection method is being developed to identify acoustic signals caused by partial occlusions in the artery.…

Signal Processing · Electrical Eng. & Systems 2024-04-25 Bansi Mandalia , Steve Greenwald , Simon Shaw , Gregory Slabaugh

Coronary Microvascular Dysfunction (CMD) is characterized by impaired vasodilation and can lead to insufficient blood flow to the myocardium during stress or exertion, affecting millions of people globally. Despite their diagnostic value,…

Computational Engineering, Finance, and Science · Computer Science 2025-08-04 Haizhou Yang , Jiyang Zhang , Ismael Z. Assi , Brahmajee K. Nallamothu , Krishna Garikipati , C. Alberto Figueroa

Bimodal stimulation, combining cochlear implant (CI) and acoustic input from the opposite ear, typically enhances speech perception but varies due to factors like temporal mismatch. Previously, we used cortical auditory evoked potentials…

Neurons and Cognition · Quantitative Biology 2025-01-29 Hanna Dolhopiatenko , Waldo Nogueira

The gold standard in the treatment of ischaemic stroke is set by evidence from randomized controlled trials, based on simple descriptions of presumptively homogeneous populations. Yet the manifest complexity of the brain's functional,…

We propose a simplified version of local molecular field (LMF) theory to treat Coulomb interactions in simulations of ionic fluids. LMF theory relies on splitting the Coulomb potential into a short-ranged part that combines with other…

Statistical Mechanics · Physics 2009-11-13 Natalia A. Denesyuk , John D. Weeks

Early identification of stroke is crucial for intervention, requiring reliable models. We proposed an efficient retinal image representation together with clinical information to capture a comprehensive overview of cardiovascular health,…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Yuqing Huang , Bastian Wittmann , Olga Demler , Bjoern Menze , Neda Davoudi

Diffuse correlation spectroscopy (DCS) is an emerging noninvasive technique that measures the tissue blood flow, by using near-infrared coherent point-source illumination to detect spectral changes. While machine learning has demonstrated…

Machine Learning · Computer Science 2024-02-02 Xi Chen , Xingda Li

Kinetic modeling enables \textit{in vivo} quantification of tracer uptake and glucose metabolism in [${}^{18}$F]Fluorodeoxyglucose ([${}^{18}$F]FDG) dynamic positron emission tomography (dPET) imaging of mice. However, kinetic modeling…

Quantitative Methods · Quantitative Biology 2025-10-27 Christian Salomonsen , Kristoffer K. Wickstrøm , Samuel Kuttner , Elisabeth Wetzer

Normalizing flows provide an elegant method for obtaining tractable density estimates from distributions by using invertible transformations. The main challenge is to improve the expressivity of the models while keeping the invertibility…

Computer Vision and Pattern Recognition · Computer Science 2023-09-07 Avideep Mukherjee , Badri Narayan Patro , Vinay P. Namboodiri

The area under the curve (AUC) of the mean cumulative function (MCF) has recently been introduced as a novel estimand for evaluating treatment effects in recurrent event settings, offering an alternative to the commonly used…

Methodology · Statistics 2025-07-22 Jiren Sun , Tuo Wang , Yanyao Yi , Ting Ye , Jun Shao , Yu Du

Low-frequency oscillations in the human circulatory system is important for basic physiology and practical applications in clinical medicine. Our objective was to study which mechanism (central or local) is responsible for changes in blood…

Tissues and Organs · Quantitative Biology 2024-11-25 Irina A. Mizeva , Natalia P. Podolyan , Oleg V. Mamontov , Anastasiia V. Sakovskaia , Alexei A. Kamshilin

Precise and fast prediction methods for ischemic areas comprised of dead tissue, core, and salvageable tissue, penumbra, in acute ischemic stroke (AIS) patients are of significant clinical interest. They play an essential role in improving…

Image and Video Processing · Electrical Eng. & Systems 2023-12-06 Luca Tomasetti , Kjersti Engan , Liv Jorunn Høllesli , Kathinka Dæhli Kurz , Mahdieh Khanmohammadi

Significance: Measuring cerebral blood flow (CBF) is crucial for diagnosing various cerebral diseases. An affordable, wearable, and fiber-free continuous-wave speckle contrast flowmetry (CW-DSCF) technique has been developed for continuous…

Quantitative Methods · Quantitative Biology 2025-02-13 Chaebeom Yeo , Xuhui Liu , Mehrana Mohtasebi , Faezeh Akbari , Faraneh Fathi , Guoqiang Yu

A lateral shear interferometer based digital holographic microscopy has been realized to study the morphology dynamics of Human red blood cells quantitatively. Here, a lateral shear interferometer is embedded with a conventional microscope…

Image and Video Processing · Electrical Eng. & Systems 2019-09-10 Shital Devinder , Ashish Lal , Tathagato Rai Dastidar , Satish Kumar Dubey

Echocardiogram (echo) is the earliest and the primary tool for identifying regional wall motion abnormalities (RWMA) in order to diagnose myocardial infarction (MI) or commonly known as heart attack. This paper proposes a novel approach,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Serkan Kiranyaz , Aysen Degerli , Tahir Hamid , Rashid Mazhar , Rayyan Ahmed , Rayaan Abouhasera , Morteza Zabihi , Junaid Malik , Ridha Hamila , Moncef Gabbouj

Pairwise Causal Discovery is the task of determining causal, anticausal, confounded or independence relationships from pairs of variables. Over the last few years, this challenging task has promoted not only the discovery of novel machine…

Machine Learning · Computer Science 2022-12-05 Felipe Giori , Flavio Figueiredo

This study proposes an approach to estimate the functional localization and connectivity from CBF and BOLD signals simultaneously measured by ASL (arterial spin labeling) MRI, especially using exploratory Structural Equation Modeling…

Neurons and Cognition · Quantitative Biology 2017-04-11 Jiancheng Zhuang

A novel approach is adopted to model cerebrospinal fluid (CSF) flow in human perivascular spaces (PVSs) surrounding brain-penetrating arteries. It is proposed that the outer PVS boundary oscillates due to brain pulsations and the arterial…

Fluid Dynamics · Physics 2025-10-24 Gregory Holba , James P. Hague , Nigel Hoggard , Marc Pradas