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Dynamical systems in the life sciences are often composed of complex mixtures of overlapping behavioral regimes. Cellular subpopulations may shift from cycling to equilibrium dynamics or branch towards different developmental fates. The…

Machine Learning · Computer Science 2025-10-13 Nathan Quiblier , Roy Friedman , Matthew Ricci

In this contribution we develop an efficient reduced order model for solving parametrized linear-quadratic optimal control problems with linear time-varying state system. The fully reduced model combines reduced basis approximations of the…

Numerical Analysis · Mathematics 2024-08-29 Hendrik Kleikamp , Lukas Renelt

Scientific analysis often relies on the ability to make accurate predictions of a system's dynamics. Mechanistic models, parameterized by a number of unknown parameters, are often used for this purpose. Accurate estimation of the model…

Dynamical Systems · Mathematics 2017-11-01 Franz Hamilton , Alun Lloyd , Kevin Flores

Incorporating a priori physics knowledge into machine learning leads to more robust and interpretable algorithms. In this work, we combine deep learning techniques and classic numerical methods for differential equations to address two…

Machine Learning · Computer Science 2026-05-04 Caitlin Ho , Andrea Arnold

Certain neural network architectures, in the infinite-layer limit, lead to systems of nonlinear differential equations. Motivated by this idea, we develop a framework for analyzing time signals based on non-autonomous dynamical equations.…

Machine Learning · Statistics 2022-04-19 Ryeongkyung Yoon , Harish S. Bhat , Braxton Osting

Time integration of stiff systems is a primary source of computational cost in combustion, hypersonics, and other reactive transport systems. This stiffness can introduce time scales significantly smaller than those associated with other…

Machine Learning · Computer Science 2026-05-19 Kamaljyoti Nath , Additi Pandey , Bryan T. Susi , Hessam Babaee , George Em Karniadakis

Many engineering problems involve learning hidden dynamics from indirect observations, where the physical processes are described by systems of partial differential equations (PDE). Gradient-based optimization methods are considered…

Numerical Analysis · Mathematics 2019-12-17 Kailai Xu , Dongzhuo Li , Eric Darve , Jerry M. Harris

In differential equation discovery algorithms, a priori expert knowledge is mainly used implicitly to constrain the form of the expected equation, making it impossible for the algorithm to truly discover equations. Instead, most…

Artificial Intelligence · Computer Science 2025-01-03 Elizaveta Ivanchik , Alexander Hvatov

Discovering symbolic differential equations from data uncovers fundamental dynamical laws underlying complex systems. However, existing methods often struggle with the vast search space of equations and may produce equations that violate…

Machine Learning · Computer Science 2026-03-11 Jianke Yang , Manu Bhat , Bryan Hu , Yadi Cao , Nima Dehmamy , Robin Walters , Rose Yu

We propose a hybrid moment method for the multi-scale kinetic equations in the framework of the regularized moment method [7]. In this method, the fourth order moment system is chosen as the governing equations in the fluid region. When…

Computational Physics · Physics 2020-04-14 Weiming Li , Peng Song , Yanli Wang

The combination of numerical integration and deep learning, i.e., ODE-net, has been successfully employed in a variety of applications. In this work, we introduce inverse modified differential equations (IMDE) to contribute to the behaviour…

Numerical Analysis · Mathematics 2021-08-16 Aiqing Zhu , Pengzhan Jin , Beibei Zhu , Yifa Tang

Hybrid approaches that combine data-driven learning with physics-based insight have shown promise for improving the reliability of industrial condition monitoring. This work develops a hybrid condition monitoring framework that integrates…

Machine Learning · Computer Science 2026-04-14 Maryam Ahang , Todd Charter , Masoud Jalayer , Homayoun Najjaran

We propose a new method to design adaptation algorithms that guarantee a certain prescribed level of performance and are applicable to systems with nonconvex parameterization. The main idea behind the method is, given the desired…

Optimization and Control · Mathematics 2007-05-23 I. Y. Tyukin , D. V. Prokhorov , Cees van Leeuwen

Differential equation discovery, a machine learning subfield, is used to develop interpretable models, particularly in nature-related applications. By expertly incorporating the general parametric form of the equation of motion and…

Machine Learning · Computer Science 2024-02-23 Alexander Hvatov , Roman Titov

We study a class of algorithms for solving bilevel optimization problems in both stochastic and deterministic settings when the inner-level objective is strongly convex. Specifically, we consider algorithms based on inexact implicit…

Optimization and Control · Mathematics 2022-07-12 Michael Arbel , Julien Mairal

Recent advances in learning dynamical systems from data have shown significant promise. However, many existing methods assume access to the full state of the system -- an assumption that is rarely satisfied in practice, where systems are…

Machine Learning · Computer Science 2026-03-10 Thibault Monsel , Onofrio Semeraro , Lionel Mathelin , Guillaume Charpiat

To improve the physical understanding and the predictions of complex dynamic systems, such as ocean dynamics and weather predictions, it is of paramount interest to identify interpretable models from coarsely and off-grid sampled…

Computational Physics · Physics 2021-05-04 Gert-Jan Both , Georges Tod , Remy Kusters

Data assimilation algorithms estimate the state of a dynamical system from partial observations, where the successful performance of these algorithms hinges on costly parameter tuning and on employing an accurate model for the dynamics.…

Machine Learning · Statistics 2026-03-24 Melissa Adrian , Daniel Sanz-Alonso , Rebecca Willett

This paper presents a data-integrated framework for learning the dynamics of fractional-order nonlinear systems in both discrete-time and continuous-time settings. The proposed framework consists of two main steps. In the first step,…

Systems and Control · Electrical Eng. & Systems 2025-06-19 Bahram Yaghooti , Chengyu Li , Bruno Sinopoli

This report presents three Moving Horizon Estimation (MHE) methods for discrete-time partitioned linear systems, i.e. systems decomposed into coupled subsystems with non-overlapping states. The MHE approach is used due to its capability of…

Systems and Control · Electrical Eng. & Systems 2024-02-01 Marcello Farina , Giancarlo Ferrari-Trecate , Riccardo Scattolini