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Tumor shape plays a critical role in influencing both growth and metastasis. We introduce a novel topological radiomic feature derived from persistent homology to characterize tumor shape, focusing on its association with time-to-event…

Methodology · Statistics 2025-12-08 Yuhyeong Jang , Tu Dan , Eric Vu , Chul Moon

Head and neck tumors and metastatic lymph nodes are crucial for treatment planning and prognostic analysis. Accurate segmentation and quantitative analysis of these structures require pixel-level annotation, making automated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 Litingyu Wang , Wenjun Liao , Shichuan Zhang , Guotai Wang

Using multimodal Magnetic Resonance Imaging (MRI) is necessary for accurate brain tumor segmentation. The main problem is that not all types of MRIs are always available in clinical exams. Based on the fact that there is a strong…

Image and Video Processing · Electrical Eng. & Systems 2021-11-11 Tongxue Zhou , Stéphane Canu , Pierre Vera , Su Ruan

Purpose: This study evaluates the impact of harmonization and multi-region feature integration on survival prediction in non-small cell lung cancer (NSCLC) patients. We assess the prognostic utility of handcrafted radiomics and pretrained…

Osteosarcoma (OS) is an aggressive primary bone malignancy. Accurate histopathological assessment of viable versus non-viable tumor regions after neoadjuvant chemotherapy is critical for prognosis and treatment planning, yet manual…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Yaxi Chen , Zi Ye , Shaheer U. Saeed , Oliver Yu , Simin Ni , Jie Huang , Yipeng Hu

The accurate automatic segmentation of gliomas and its intra-tumoral structures is important not only for treatment planning but also for follow-up evaluations. Several methods based on 2D and 3D Deep Neural Networks (DNN) have been…

Image and Video Processing · Electrical Eng. & Systems 2020-01-28 Parth Natekar , Avinash Kori , Ganapathy Krishnamurthi

Although the combined treatment of surgery, radiotherapy, chemotherapy, and emerging target therapy has significantly improved the outcomes of patients with head and neck cancer, distant metastasis remains the leading cause of treatment…

Quantitative Methods · Quantitative Biology 2025-12-02 Nuo Tong , Changhao Liu , Zizhao Tang , Feifan Sun , Yingping Li , Shuiping Gou , Mei Shi

Accurate segmentation of brain tumors from 3D multimodal MRI is vital for diagnosis and treatment planning across diverse brain tumors. This paper addresses the challenges posed by the BraTS 2023, presenting a unified transfer learning…

Image and Video Processing · Electrical Eng. & Systems 2024-12-12 Ramy A. Zeineldin , Franziska Mathis-Ullrich

Background and Purpose: Pediatric low-grade glioma (pLGG) is the most common type of brain tumor in children, and identification of molecular markers for pLGG is crucial for successful treatment planning. Convolutional Neural Network (CNN)…

Computer Vision and Pattern Recognition · Computer Science 2023-10-26 Khashayar Namdar , Matthias W. Wagner , Kareem Kudus , Cynthia Hawkins , Uri Tabori , Brigit Ertl-Wagner , Farzad Khalvati

We investigate the potential of stochastic neural networks for learning effective waveform-based acoustic models. The waveform-based setting, inherent to fully end-to-end speech recognition systems, is motivated by several comparative…

Machine Learning · Statistics 2021-08-17 Dino Oglic , Zoran Cvetkovic , Peter Sollich

Purpose: The segmentation of brain tumors is one of the most active areas of medical image analysis. While current methods perform superhuman on benchmark data sets, their applicability in daily clinical practice has not been evaluated. In…

Image and Video Processing · Electrical Eng. & Systems 2020-12-17 Sabine Müller , Joachim Weickert , Norbert Graf

In recent years Artificial Intelligence has emerged as a fundamental tool in medical applications. Despite this rapid development, deep neural networks remain black boxes that are difficult to explain, and this represents a major limitation…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Tommaso Torda , Andrea Ciardiello , Simona Gargiulo , Greta Grillo , Simone Scardapane , Cecilia Voena , Stefano Giagu

Brain tumor segmentation is a critical task for patient's disease management. In order to automate and standardize this task, we trained multiple U-net like neural networks, mainly with deep supervision and stochastic weight averaging, on…

Image and Video Processing · Electrical Eng. & Systems 2020-11-30 Theophraste Henry , Alexandre Carre , Marvin Lerousseau , Theo Estienne , Charlotte Robert , Nikos Paragios , Eric Deutsch

Discriminative convolutional neural networks (CNNs), for which a voxel-wise conditional Multinoulli distribution is assumed, have performed well in many brain lesion segmentation tasks. For a trained discriminative CNN to be used in…

Image and Video Processing · Electrical Eng. & Systems 2021-02-22 Kevin Raina

Glioma is the most common and aggressive brain tumor. Magnetic resonance imaging (MRI) plays a vital role to evaluate tumors for the arrangement of tumor surgery and the treatment of subsequent procedures. However, the manual segmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-03-23 Wenbo Zhang , Guang Yang , He Huang , Weiji Yang , Xiaomei Xu , Yongkai Liu , Xiaobo Lai

Brain tumor segmentation is a fundamental step in assessing a patient's cancer progression. However, manual segmentation demands significant expert time to identify tumors in 3D multimodal brain MRI scans accurately. This reliance on manual…

Image and Video Processing · Electrical Eng. & Systems 2024-05-07 Fadillah Maani , Anees Ur Rehman Hashmi , Numan Saeed , Mohammad Yaqub

For patients suffering from brain tumor, prognosis estimation and treatment decisions are made by a multidisciplinary team based on a set of preoperative MR scans. Currently, the lack of standardized and automatic methods for tumor…

Objective: Deep Learning-based Radiomics (DLR) has achieved great success in medical image analysis and has been considered a replacement for conventional radiomics that relies on handcrafted features. In this study, we aimed to explore the…

Image and Video Processing · Electrical Eng. & Systems 2022-09-20 Bingxin Gu , Mingyuan Meng , Lei Bi , Jinman Kim , David Dagan Feng , Shaoli Song

Deep convolutional neural network (CNN) achieves remarkable performance for medical image analysis. UNet is the primary source in the performance of 3D CNN architectures for medical imaging tasks, including brain tumor segmentation. The…

Image and Video Processing · Electrical Eng. & Systems 2020-11-30 Parvez Ahmad , Saqib Qamar , Linlin Shen , Adnan Saeed

The anatomical location of imaging features is of crucial importance for accurate diagnosis in many medical tasks. Convolutional neural networks (CNN) have had huge successes in computer vision, but they lack the natural ability to…

Computer Vision and Pattern Recognition · Computer Science 2016-11-01 Mohsen Ghafoorian , Nico Karssemeijer , Tom Heskes , Inge van Uden , Clara Sanchez , Geert Litjens , Frank-Erik de Leeuw , Bram van Ginneken , Elena Marchiori , Bram Platel
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