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The Quantum Approximate Optimization Algorithm (QAOA) has enjoyed increasing attention in noisy intermediate-scale quantum computing due to its application to combinatorial optimization problems. Because combinatorial optimization problems…

Optimization and Control · Mathematics 2024-01-18 Yunsoo Ha , Sara Shashaani , Matt Menickelly

The feedback-based algorithm for quantum optimization (FALQON) has recently been proposed to solve quadratic unconstrained binary optimization problems. This paper efficiently generalizes FALQON to tackle quadratic constrained binary…

Quantum Physics · Physics 2025-04-15 Salahuddin Abdul Rahman , Özkan Karabacak , Rafal Wisniewski

Portfolio optimization is one of the most studied optimization problems at the intersection of quantum computing and finance. In this work, we develop the first quantum formulation for a portfolio optimization problem with higher-order…

Quantum Physics · Physics 2026-01-28 Valter Uotila , Julia Ripatti , Bo Zhao

Quantum linear system algorithms (QLSAs) have the potential to speed up algorithms that rely on solving linear systems. Interior Point Methods (IPMs) yield a fundamental family of polynomial-time algorithms for solving optimization…

Optimization and Control · Mathematics 2023-03-22 Zeguan Wu , Mohammadhossein Mohammadisiahroudi , Brandon Augustino , Xiu Yang , Tamás Terlaky

Quadratic Unconstrained Binary Optimization (QUBO) problems are prevalent in various applications and are known to be NP-hard. The seminal work of Goemans and Williamson introduced a semidefinite programming (SDP) relaxation for such…

Quantum Physics · Physics 2025-10-10 Haomu Yuan , Daniel Stilck França , Ilia Luchnikov , Egor Tiunov , Tobias Haug , Leandro Aolita

Solving combinatorial optimization problems on current noisy quantum devices is currently being advocated for (and restricted to) binary polynomial optimization with equality constraints via quantum heuristic approaches. This is achieved…

Quantum Physics · Physics 2021-02-04 Claudio Gambella , Andrea Simonetto

The bin packing is a well-known NP-Hard problem in the domain of artificial intelligence, posing significant challenges in finding efficient solutions. Conversely, recent advancements in quantum technologies have shown promising potential…

Quantum Physics · Physics 2024-01-17 Lorenzo Cellini , Antonio Macaluso , Michele Lombardi

This paper studies quantum optimization baselines for the Generalized Traveling Salesman Problem (GTSP), a clustered routing problem that naturally models variant selection and sequencing problems under discrete alternatives. We propose a…

Abstraction layers are of paramount importance in software architecture, as they shield the higher-level formulation of payload computations from lower-level details. Since quantum computing (QC) introduces many such details that are often…

Quantum Physics · Physics 2024-09-04 Lukas Schmidbauer , Karen Wintersperger , Elisabeth Lobe , Wolfgang Mauerer

The LogQ algorithm encodes Quadratic Unconstrained Binary Optimization (QUBO) problems, which are often encountered in the industry (portfolio optimization, fleet optimization, charging stations, etc.). It was developed within the framework…

Optimization and Control · Mathematics 2026-04-15 Jérémie Messud , Yagnik Chatterjee

Quantum annealing aims at solving optimization problems of practical relevance using quantum-computing hardware. Problems of interest are typically formulated in terms of quadratic unconstrained binary optimization (QUBO) Hamiltonians.…

AlphaFold has achieved groundbreaking advancements in protein structure prediction, exerting profound influence across biology, medicine, and drug discovery. However, its reliance on multiple sequence alignment (MSA) is inherently…

Quantum Physics · Physics 2025-06-03 Rong Chen , Quan-Xin Mei , Wen-Ding Zhao , Lin Yao , Hao-Xiang Yang , Shun-Yao Zhang , Jiao Chen , Hong-Lin Li

Critical decision-making issues in science, engineering, and industry are based on combinatorial optimization; however, its application is inherently limited by the NP-hard nature of the problem. A specialized paradigm of analogue quantum…

Quantum Physics · Physics 2026-02-04 Rudraksh Sharma , Ravi Katukam , Arjun Nagulapally

Feature selection is crucial for enhancing the accuracy and efficiency of machine learning (ML) models. This work investigates the utility of quantum annealing for the feature selection process in an ML-pipeline, used for maximizing the…

Quantum Physics · Physics 2024-12-02 Daniel Pranjic , Bharadwaj Chowdary Mummaneni , Christian Tutschku

The increasing complexity of industrial scheduling and transport routing problems motivates the study of alternative optimization formulations and computational paradigms. In this work, we study how higher-order unconstrained binary…

Quantum Amplitude Amplification (QAA), the generalization of Grover's algorithm, is capable of yielding optimal solutions to combinatorial optimization problems with high probabilities. In this work we extend the conventional 2-dimensional…

Quantum Physics · Physics 2026-01-16 Daniel Koch , Brian Pardo , Kip Nieman

Quantum annealing technologies aim to solve computational optimization and sampling problems. QPU (Quantum Processing Unit) machines such as the D-Wave system use the QUBO (Quadratic Unconstrained Binary Optimization) formula to define…

Quantum Physics · Physics 2022-03-28 Toufan D. Tambunan , Andriyan B. Suksmono , Ian J. M. Edward , Rahmat Mulyawan

The Optimum-Path Forest is a graph-based framework for designing classifiers that exploit inter-sample connectivity. A particular variant constructs decision boundaries based on prototypes computed by a Minimum Spanning Tree (MST) over the…

A range of quantum algorithms, especially those leveraging variational parameterization and circuit-based optimization, are being studied as alternatives for solving classically intractable combinatorial optimization problems (COPs).…

Quantum Physics · Physics 2025-06-18 Monit Sharma , Hoong Chuin Lau

The emergence of huge-scale, data-intensive linear optimization (LO) problems in applications such as machine learning has driven the need for more computationally efficient interior point methods (IPMs). While conventional IPMs are…

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