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In this study, we generate and maintain a database of 10 million virtual lipids through METiS's in-house de novo lipid generation algorithms and lipid virtual screening techniques. These virtual lipids serve as a corpus for pre-training,…

Computation and Language · Computer Science 2025-05-06 Tianhao Yu , Cai Yao , Zhuorui Sun , Feng Shi , Lin Zhang , Kangjie Lyu , Xuan Bai , Andong Liu , Xicheng Zhang , Jiali Zou , Wenshou Wang , Chris Lai , Kai Wang

Tutoring systems improve learning through tailored interventions, such as worked examples, but often suffer from the aptitude-treatment interaction effect where low prior knowledge learners benefit more. We applied the ICAP learning theory…

Human-Computer Interaction · Computer Science 2026-02-20 Sutapa Dey Tithi , Xiaoyi Tian , Ally Limke , Min Chi , Tiffany Barnes

As large language models (LLMs) become more common in educational tools and programming environments, questions arise about how these systems should interact with users. This study investigates how different interaction styles with…

Human-Computer Interaction · Computer Science 2025-07-08 Kai Deng

In this study, we reveal an in-context learning (ICL) capability of multilingual large language models (LLMs): by translating the input to several languages, we provide Parallel Input in Multiple Languages (PiM) to LLMs, which significantly…

Computation and Language · Computer Science 2025-06-04 Yongyu Mu , Peinan Feng , Zhiquan Cao , Yuzhang Wu , Bei Li , Chenglong Wang , Tong Xiao , Kai Song , Tongran Liu , Chunliang Zhang , Jingbo Zhu

Intelligent tutoring agents powered by large language models (LLMs) have been increasingly explored to deliver personalized knowledge in areas such as language learning and science education. However, their capabilities in guiding users to…

Computation and Language · Computer Science 2025-05-27 Jian Wang , Yinpei Dai , Yichi Zhang , Ziqiao Ma , Wenjie Li , Joyce Chai

We provide ongoing results from the development of a personalized learning system integrated into a serious game. Given limited instructor resources, the use of computerized systems to help tutor students offers a way to provide higher…

Computers and Society · Computer Science 2023-05-29 Ying Tang , Ryan Hare

Recent advancements in machine learning provide methods to train autonomous agents capable of handling the increasing complexity of sequential decision-making in robotics. Imitation Learning (IL) is a prominent approach, where agents learn…

Robotics · Computer Science 2025-05-01 Jonas Werner , Kun Chu , Cornelius Weber , Stefan Wermter

This paper addresses the challenge of improving interaction quality in dialogue based learning by detecting and recommending effective pedagogical strategies in tutor student conversations. We introduce PedagoSense, a pedology grounded…

Computation and Language · Computer Science 2026-02-03 Shahem Sultan , Shahem Fadi , Yousef Melhim , Ibrahim Alsarraj , Besher Hassan

There are growing promises that Large Language Models (LLMs) can support students' learning by providing explanations, feedback, and guidance. However, despite their rapid adoption and widespread attention, there is still limited empirical…

Large language models (LLMs) enable increasingly capable tutoring-style conversational agents, yet effective tutoring requires sensitivity to learners' affective and cognitive states beyond text alone. Facial expressions provide immediate…

Human-Computer Interaction · Computer Science 2026-04-20 Shuangquan Feng , Laura Fleig , Ruisen Tu , Philip Chi , Edmund Bu , Melinda Ozel , Junhua Ma , Teng Fei , Virginia R. de Sa

Massively multilingual sentence representation models, e.g., LASER, SBERT-distill, and LaBSE, help significantly improve cross-lingual downstream tasks. However, the use of a large amount of data or inefficient model architectures results…

Computation and Language · Computer Science 2024-05-31 Zhuoyuan Mao , Chenhui Chu , Sadao Kurohashi

The widespread availability of large language models (LLMs), such as ChatGPT, has significantly impacted education, raising both opportunities and challenges. Students can frequently interact with LLM-powered, interactive learning tools,…

Artificial Intelligence · Computer Science 2026-03-06 Hunter McNichols , Fareya Ikram , Andrew Lan

This research-to-practice work-in-progress (WIP) paper presents an AI-enabled smart tutor designed to provide homework assessment and feedback for students in an undergraduate circuit analysis course. We detail the tutor's design philosophy…

Computers and Society · Computer Science 2025-06-11 Liangliang Chen , Huiru Xie , Jacqueline Rohde , Ying Zhang

Large language models (LLMs) demonstrate their promise in tackling complicated practical challenges by combining action-based policies with chain of thought (CoT) reasoning. Having high-quality prompts on hand, however, is vital to the…

Machine Learning · Computer Science 2024-03-01 Xue Yan , Yan Song , Xinyu Cui , Filippos Christianos , Haifeng Zhang , David Henry Mguni , Jun Wang

Federated instruction tuning enables multiple clients to collaboratively fine-tune a shared large language model (LLM) that can follow humans' instructions without directly sharing raw data. However, existing literature impractically…

Computation and Language · Computer Science 2024-09-12 Rui Ye , Rui Ge , Yuchi Fengting , Jingyi Chai , Yanfeng Wang , Siheng Chen

Cognitive diagnosis (CD) plays a crucial role in intelligent education, evaluating students' comprehension of knowledge concepts based on their test histories. However, current CD methods often model students, exercises, and knowledge…

Computation and Language · Computer Science 2025-05-21 Weiming Zhang , Lingyue Fu , Qingyao Li , Kounianhua Du , Jianghao Lin , Jingwei Yu , Wei Xia , Weinan Zhang , Ruiming Tang , Yong Yu

We present DIALIGHT, a toolkit for developing and evaluating multilingual Task-Oriented Dialogue (ToD) systems which facilitates systematic evaluations and comparisons between ToD systems using fine-tuning of Pretrained Language Models…

Computation and Language · Computer Science 2024-01-05 Songbo Hu , Xiaobin Wang , Zhangdie Yuan , Anna Korhonen , Ivan Vulić

Large language models (LLMs) open up new horizons for sequential recommendations, owing to their remarkable language comprehension and generation capabilities. However, there are still numerous challenges that should be addressed to…

Information Retrieval · Computer Science 2024-03-29 Yuling Wang , Changxin Tian , Binbin Hu , Yanhua Yu , Ziqi Liu , Zhiqiang Zhang , Jun Zhou , Liang Pang , Xiao Wang

Large Language Models (LLMs) demonstrate strong performance in real-world applications, yet existing open-source instruction datasets often concentrate on narrow domains, such as mathematics or coding, limiting generalization and widening…

Computation and Language · Computer Science 2025-06-16 Jijie Li , Li Du , Hanyu Zhao , Bo-wen Zhang , Liangdong Wang , Boyan Gao , Guang Liu , Yonghua Lin

How can language learning systems be developed for languages that lack sufficient training resources? This challenge is increasingly faced by developers across the African continent who aim to build AI systems capable of understanding and…