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Missing data is a common problem in medical research, and is commonly addressed using multiple imputation. Although traditional imputation methods allow for valid statistical inference when data are missing at random (MAR), their…

Imputing missing values is an important preprocessing step in data analysis, but the literature offers little guidance on how to choose between different imputation models. This letter suggests adopting the imputation model that generates a…

Methodology · Statistics 2021-07-13 Moritz Marbach

Multiple imputation is widely used to handle missing data. Although Rubin's combining rule is simple, it is not clear whether or not the standard multiple imputation inference is consistent when coupled with the commonly-used full sample…

Methodology · Statistics 2023-01-03 Qian Guan , Shu Yang

Missing data is a common concern in health datasets, and its impact on good decision-making processes is well documented. Our study's contribution is a methodology for tackling missing data problems using a combination of synthetic dataset…

Machine Learning · Computer Science 2022-11-08 Gift Khangamwa , Terence L. van Zyl , Clint J. van Alten

We present an approach for imputation of missing items in multivariate categorical data nested within households. The approach relies on a latent class model that (i) allows for household level and individual level variables, (ii) ensures…

Methodology · Statistics 2018-07-05 Olanrewaju Akande , Jerome Reiter , Andrés F. Barrientos

Key to effective generic, or "black-box", variational inference is the selection of an approximation to the target density that balances accuracy and speed. Copula models are promising options, but calibration of the approximation can be…

Methodology · Statistics 2022-07-01 Michael Stanley Smith , Rubén Loaiza-Maya

Continuous proportions measured on the same experimental unit often pose two challenges: interior outliers that inflate variance beyond the beta ceiling and residual dependence that invalidates independent-margin models. We introduce a…

Methodology · Statistics 2025-11-14 Divan A. Burger , Janet van Niekerk , Peter C. le Roux , Morgan J. Raath-Krüger

In this paper, a Bayesian semiparametric copula approach is used to model the underlying multivariate distribution $F_{true}$. First, the Dirichlet process is constructed on the unknown marginal distributions of $F_{true}$. Then a Gaussian…

Methodology · Statistics 2019-07-05 Luai Al-Labadi , Forough Fazeli Asl , Zahra Saberi

This article proposes a graphical model that handles mixed-type, multi-group data. The motivation for such a model originates from real-world observational data, which often contain groups of samples obtained under heterogeneous conditions…

Methodology · Statistics 2023-01-02 Sjoerd Hermes , Joost van Heerwaarden , Pariya Behrouzi

In this paper, we derive copula-based and empirical dependency models (DMs) for simulating non-independent variables, and then propose a new way for determining the distribution of the model outputs conditional on every subset of inputs.…

Statistics Theory · Mathematics 2022-09-12 Matieyendou Lamboni

A wide range of systems exhibit high dimensional incomplete data. Accurate estimation of the missing data is often desired, and is crucial for many downstream analyses. Many state-of-the-art recovery methods involve supervised learning…

Computer Vision and Pattern Recognition · Computer Science 2019-03-15 Adrian V. Dalca , John Guttag , Mert R. Sabuncu

Methods to handle missing data have been extensively explored in the context of estimation and descriptive studies, with multiple imputation being the most widely used method in clinical research. However, in the context of clinical risk…

Methodology · Statistics 2024-11-25 Junhui Mi , Rahul D. Tendulkar , Sarah M. C. Sittenfeld , Sujata Patil , Emily C. Zabor

We consider a binary unsupervised classification problem where each observation is associated with an unobserved label that we want to retrieve. More precisely, we assume that there are two groups of observation: normal and abnormal. The…

Machine Learning · Statistics 2011-05-05 Stevenn Volant , Marie-Laure Martin Magniette , Stéphane Robin

Multiple imputation is a highly recommended technique to deal with missing data, but the application to longitudinal datasets can be done in multiple ways. When a new wave of longitudinal data arrives, we can treat the combined data of…

Methodology · Statistics 2026-05-18 X. M. Kavelaars , S. van Buuren , J. R. van Ginkel

The non-identifiability of the competing risks model requires researchers to work with restrictions on the model to obtain informative results. We present a new identifiability solution based on an exclusion restriction. Many areas of…

Methodology · Statistics 2023-09-06 Munir Hiabu , Simon M. S. LU , Ralf A. Wilke

Copulas provide a modular parameterization of multivariate distributions that decouples the modeling of marginals from the dependencies between them. Gaussian Mixture Copula Model (GMCM) is a highly flexible copula that can model many kinds…

Methodology · Statistics 2021-09-29 Siva Rajesh Kasa , Vaibhav Rajan

Copulas, generalized estimating equations, and generalized linear mixed models promote the analysis of grouped data where non-normal responses are correlated. Unfortunately, parameter estimation remains challenging in these three…

Methodology · Statistics 2024-10-16 Sarah S. Ji , Benjamin B. Chu , Hua Zhou , Kenneth Lange

We study an unbiased estimator for the density of a sum of random variables that are simulated from a computer model. A numerical study on examples with copula dependence is conducted where the proposed estimator performs favourably in…

Statistics Theory · Mathematics 2018-09-19 Patrick J. Laub , Robert Salomone , Zdravko I. Botev

Modeling the ratio of two dependent components as a function of covariates is a frequently pursued objective in observational research. Despite the high relevance of this topic in medical studies, where biomarker ratios are often used as…

Methodology · Statistics 2023-12-04 Moritz Berger , Nadja Klein , Michael Wagner , Matthias Schmid

The standard quantile regression model assumes a linear relationship at the quantile of interest and that all variables are observed. We relax these assumptions by considering a partial linear model while allowing for missing linear…

Methodology · Statistics 2016-06-07 Ben Sherwood