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With the rapid development of quantum computers, quantum algorithms have been studied extensively. However, quantum algorithms tackling statistical problems are still lacking. In this paper, we propose a novel non-oracular quantum adaptive…

Methodology · Statistics 2021-07-20 Wenxuan Zhong , Yuan Ke , Ye Wang , Yongkai Chen , Jinyang Chen , Ping Ma

Quantum annealing algorithms belong to the class of metaheuristic tools, applicable for solving binary optimization problems. Hardware implementations of quantum annealing, such as the quantum annealing machines produced by D-Wave Systems,…

Quantum Physics · Physics 2017-09-18 Florian Neukart , David Von Dollen , Christian Seidel , Gabriele Compostella

Quantum Annealing (QA) is a computational framework where a quantum system's continuous evolution is used to find the global minimum of an objective function over an unstructured search space. It can be seen as a general metaheuristic for…

Quantum Physics · Physics 2022-02-04 Arthur Braida , Simon Martiel , Ioan Todinca

Quantum enhanced optimization of classical cost functions is a central theme of quantum computing due to its high potential value in science and technology. The variational quantum eigensolver (VQE) and the quantum approximate optimization…

Quantum Physics · Physics 2024-11-27 Giuseppe Scriva , Nikita Astrakhantsev , Sebastiano Pilati , Guglielmo Mazzola

A hybrid quantum-classical algorithm is a computational scheme in which quantum circuits are used to extract information that is then processed by a classical routine to guide subsequent quantum operations. These algorithms are especially…

Quantum Physics · Physics 2025-09-03 Alon Levi , Ziv Ossi , Eliahu Cohen , Amit Te'eni

Conformation generation, also known as molecular unfolding (MU), is a crucial step in structure-based drug design, remaining a challenging combinatorial optimization problem. Quantum annealing (QA) has shown great potential for solving…

Quantum annealing is a method developed to solve combinatorial optimization problems by utilizing quantum bits. Solving such problems corresponds to minimizing a cost function defined over binary variables. However, in many practical cases,…

Quantum Physics · Physics 2025-06-26 Seiya Endo , Shohei Kawakatsu , Hiromichi Matsuyama , Kohei Suzuki , Yuichiro Matsuzaki

Recent work [Sachdeva et al.] presented an iterative hybrid quantum variational optimization algorithm designed by Q-CTRL and executed on IBM gate-based quantum processing units (QPUs), claiming a significant performance advantage against a…

Quantum Physics · Physics 2024-06-28 Catherine C. McGeoch , Kevin Chern , Pau Farré , Andrew K. King

A longstanding computational challenge is the accurate simulation of many-body particle systems. Especially for deriving key characteristics of high-impact but complex systems such as battery materials and high entropy alloys (HEA). While…

Quantum Physics · Physics 2025-11-20 Koen Mesman , Yinglu Tang , Matthias Moller , Boyang Chen , Sebastian Feld

Quantum simulation of strongly correlated systems is potentially the most feasible useful application of near-term quantum computers. Minimizing quantum computational resources is crucial to achieving this goal. A promising class of…

Quantum Physics · Physics 2023-06-14 V. O. Shkolnikov , Nicholas J. Mayhall , Sophia E. Economou , Edwin Barnes

A computation in adiabatic quantum computing is implemented by traversing a path of nondegenerate eigenstates of a continuous family of Hamiltonians. We introduce a method that traverses a discretized form of the path: At each step we apply…

Quantum Physics · Physics 2009-08-14 S. Boixo , E. Knill , R. D. Somma

This study describes a hybrid quantum-classical computational approach for designing synthesizable deuterated $Alq_3$ emitters possessing desirable emission quantum efficiencies (QEs). This design process has been performed on the…

Recent advances in quantum computing devices have brought attention to hybrid quantum-classical algorithms like the Variational Quantum Eigensolver (VQE) as a potential route to practical quantum advantage in chemistry. However, it is not…

Recent advances in quantum technology have led to the development and manufacturing of experimental programmable quantum annealing optimizers that contain hundreds of quantum bits. These optimizers, named `D-Wave' chips, promise to solve…

Quantum Physics · Physics 2015-10-23 Victor Martin-Mayor , Itay Hen

Quantum chemical calculations have attracted much attention as a practical application of quantum computing. Quantum computers can prepare superpositions of electronic states with various numbers of electrons on qubits. This special feature…

Chemical Physics · Physics 2024-03-29 Soichi Shirai , Takahiro Horiba , Hirotoshi Hirai

We present a new hybrid quantum-classical algorithm for optimizing unitary coupled-cluster (UCC) wave functions deemed the projective quantum eigensolver (PQE), amenable to near-term noisy quantum hardware. Contrary to variational quantum…

Quantum Physics · Physics 2021-08-10 Nicholas H. Stair , Francesco A. Evangelista

Quantum chemistry is one of the most promising applications of quantum computers in the near future. For noisy intermediate-scale quantum devices, the quantum-classical hybrid framework based on the variational quantum eigensolver (VQE) has…

Variational Quantum Eigensolver (VQE) provides a powerful solution for approximating molecular ground state energies by combining quantum circuits and classical computers. However, estimating probabilistic outcomes on quantum hardware…

Quantum Physics · Physics 2024-05-07 Senwei Liang , Linghua Zhu , Xiaolin Liu , Chao Yang , Xiaosong Li

We investigate the computational efficiency and thermodynamic cost of the D-Wave quantum annealer under reverse-annealing with and without pausing. Our experimental results demonstrate that the combination of reverse-annealing and pausing…

Quantum Physics · Physics 2024-02-27 Tomasz Śmierzchalski , Zakaria Mzaouali , Sebastian Deffner , Bartłomiej Gardas

Quantum computing is entering a transformative phase with the emergence of logical quantum processors, which hold the potential to tackle complex problems beyond classical capabilities. While significant progress has been made, applying…

Quantum Physics · Physics 2025-01-29 Shunya Minami , Kouhei Nakaji , Yohichi Suzuki , Alán Aspuru-Guzik , Tadashi Kadowaki