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Longitudinal study designs are indispensable for studying disease progression. Inferring covariate effects from longitudinal data, however, requires interpretable methods that can model complicated covariance structures and detect nonlinear…

Machine Learning · Statistics 2022-10-27 Juho Timonen , Henrik Mannerström , Aki Vehtari , Harri Lähdesmäki

Accurate and efficient plasma models are essential to understand and control experimental devices. Existing magnetohydrodynamic or kinetic models are nonlinear, computationally intensive, and can be difficult to interpret, while often only…

Plasma Physics · Physics 2020-03-04 Alan A. Kaptanoglu , Kyle D. Morgan , Chris J. Hansen , Steven L. Brunton

In this study, we present a non-invasive glucose prediction system that integrates Near-Infrared (NIR) spectroscopy and millimeter-wave (mm-wave) sensing. We employ a Mixed Linear Model (MixedLM) to analyze the association between mm-wave…

Machine Learning · Computer Science 2024-09-12 Yuyang Sun , Panagiotis Kosmas

In this paper, we study the problem of blood glucose forecasting and provide a deep personalized solution. Predicting blood glucose level in people with diabetes has significant value because health complications of abnormal glucose level…

Machine Learning · Computer Science 2021-09-08 Mohammadreza Armandpour , Brian Kidd , Yu Du , Jianhua Z. Huang

Accurate prediction of future blood glucose (BG) levels can effectively improve BG management for people living with diabetes, thereby reducing complications and improving quality of life. The state of the art of BG prediction has been…

Machine Learning · Computer Science 2024-02-27 Chengzhe Piao , Taiyu Zhu , Stephanie E Baldeweg , Paul Taylor , Pantelis Georgiou , Jiahao Sun , Jun Wang , Kezhi Li

Hypoglycemia is a severe condition of decreased blood glucose, specifically below 70 mg/dL (3.9 mmol/L). This condition can often be asymptomatic and challenging to predict in individuals with type 1 diabetes (T1D). Research on hypoglycemic…

Quantitative Methods · Quantitative Biology 2026-03-24 Vaibhav Gupta , Florian Grensing , Beyza Cinar , Louisa van den Boom , Maria Maleshkova

To best of the authors knowledge, this article presents the first-ever non-invasive glucometer that takes into account serum glucose for high accuracy. In case of blood glucose measurement, serum glucose value has always been considered…

Signal Processing · Electrical Eng. & Systems 2021-06-28 Prateek Jain , Amit M Joshi , Navneet Agrawal , Saraju Mohanty

Standard objective functions used during the training of neural-network-based predictive models do not consider clinical criteria, leading to models that are not necessarily clinically acceptable. In this study, we look at this problem from…

Quantitative Methods · Quantitative Biology 2020-09-24 Maxime De Bois , Mounîm A. El Yacoubi , Mehdi Ammi

We apply Gaussian process (GP) regression, which provides a powerful non-parametric probabilistic method of relating inputs to outputs, to survival data consisting of time-to-event and covariate measurements. In this context, the covariates…

Statistics Theory · Mathematics 2014-09-08 James E. Barrett , Anthony C. C. Coolen

The paper proposes an alternative way to achieve the Internal Model Principle (IMP) in contrast to the standard way, where a model of the signal one wishes to track/reject is directly substituted into the closed-loop. The proposed…

Systems and Control · Electrical Eng. & Systems 2025-05-26 Can Kutlu Yüksel , Tomáš Vyhlídal , Silviu-Iulian Niculescu

Reconstructing gene regulatory networks from large-scale heterogeneous data is a key challenge in biology. In multi-omics data analysis, networks based on pairwise statistical association measures remain popular, as they are easy to build…

Methodology · Statistics 2025-06-11 Ekaterina Tomilina , Florence Jaffrézic , Gildas Mazo

The Gaussian process (GP) regression model is a widely employed surrogate modeling technique for computer experiments, offering precise predictions and statistical inference for the computer simulators that generate experimental data.…

Methodology · Statistics 2024-04-02 Lulu Kang , Yuanxing Cheng , Yiwei Wang , Chun Liu

Diabetes cases worldwide have risen steadily over the past decades, lending urgency to the search for more efficient, effective, and personalized ways to treat the disease. Current treatment strategies, however, may fail to maintain…

Tissues and Organs · Quantitative Biology 2014-03-05 S. M. Kissler , C. Cichowitz , S. Sankaranarayanan , D. M. Bortz

Background and objective: Diabetes is a chronic pathology which is affecting more and more people over the years. It gives rise to a large number of deaths each year. Furthermore, many people living with the disease do not realize the…

Blood glucose value prediction is an important task in diabetes management. While it is reported that glucose concentration is sensitive to social context such as mood, physical activity, stress, diet, alongside the influence of diabetes…

Machine Learning · Statistics 2019-09-05 Mohammad Akbari , Rumi Chunara

Diabetes Mellitus is a metabolic disorder which may result in severe and potentially fatal complications if not well-treated and monitored. In this study, a quantitative analysis of the data collected using CGM (Continuous Glucose…

Quantitative Methods · Quantitative Biology 2023-08-15 Giulia Elena Aliffi , Giovanni Nastasi , Vittorio Romano , Dario Pitocco , Alessandro Rizzi , Elvin J. Moore , Andrea De Gaetano

Model-based feedforward control improves tracking performance of motion systems, provided that the model describing the inverse dynamics is of sufficient accuracy. Model sets, such as neural networks (NNs) and physics-guided neural networks…

Systems and Control · Electrical Eng. & Systems 2022-04-04 Max Bolderman , Mircea Lazar , Hans Butler

The positive link prediction (PLP) problem is formulated in a system identification framework: we consider dynamic graphical models for auto-regressive moving-average (ARMA) Gaussian random processes. For the identification of the…

Optimization and Control · Mathematics 2020-04-30 Daniele Alpago , Mattia Zorzi , Augusto Ferrante

Hypoglycemia is common and potentially dangerous among those treated for diabetes. Electronic health records (EHRs) are important resources for hypoglycemia surveillance. In this study, we report the development and evaluation of deep…

Computation and Language · Computer Science 2018-11-30 Yonghao Jin , Fei Li , Hong Yu

The PID controller parameters can be adjusted in such a manner that it gives the desired frequency response and the results are found using the Bodes integral formula in order to adjust the slope of the nyquist curve in a desired manner.…

Systems and Control · Computer Science 2013-01-01 Anish Acharya , Debatri Mitra , Kaushik Halder