Related papers: Vagus nerve stimulation: Laying the groundwork for…
Vagus nerve stimulation (VNS) has emerged as a promising therapeutic intervention across various neurological and psychiatric conditions, including epilepsy, depression, and stroke rehabilitation; however, its mechanisms of action on neural…
Background: The chronically instrumented pregnant sheep has been used as a model of human fetal development and responses to pathophysiologic stimuli. This is due to the unique amenability of the unanesthetized fetal sheep to the surgical…
An electrocardiogram (ECG)-derived heart rate variability (HRV) index reliably tracks the inflammatory response induced by low-dose lipopolysaccharide (LPS) in near-term sheep fetuses. We evaluated the effect of vagus nerve stimulation…
Response variability limits the clinical utility of transcutaneous auricular vagus nerve stimulation (taVNS) for negative symptoms in treatment-resistant schizophrenia (TRS). This study aimed to develop an electroencephalography (EEG)-based…
Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…
An implanted device for brain-responsive neurostimulation (RNS System) is approved as an effective treatment to reduce seizures in adults with medically-refractory focal epilepsy. Clinical trials of the RNS System demonstrate…
Early management and better clinical outcomes for epileptic patients depend on seizure prediction. The accuracy and false alarm rates of existing systems are often compromised by their dependence on static thresholds and basic…
Epilepsy is a dynamic and complex neurological disease affecting about 1% of the worldwide population, among which 30% of the patients are drug-resistant. Epilepsy is characterized by recurrent episodes of paroxysmal neural discharges (the…
Neurostimulation is a promising therapy for abating epileptic seizures. However, it is extremely difficult to identify optimal stimulation patterns experimentally. In this study human recordings are used to develop a functional 24 neuron…
Epilepsy is a common neurological disorder characterized by recurrent seizures accompanied by excessive synchronous brain activity. The process of structural and functional brain alterations leading to increased seizure susceptibility and…
Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…
In the emerging research field of bioelectronic medicine, it has been indicated that neuromodulation of the Vagus Nerve (VN) has the potential to treat various conditions such as epilepsy, depression, and autoimmune diseases. In order to…
Epilepsy is a neurological illness that is characterised by continuous spasms of shaking, sometimes known as convulsions. Although there are effective treatments for epilepsy, such as drugs and surgery, there is still a group of individuals…
The rapid growth of the drone industry, particularly in the use of small unmanned aerial systems (sUAS) and unmanned aerial vehicles (UAVs), requires the development of advanced training protocols for remote pilots. Remote pilots must…
Peripheral Nerve Stimulation (PNS) constrains the clinical performance of Magnetic Resonance and Particle Imaging (MRI and MPI) systems. Extensive magneto-stimulation studies have been carried out recently in the field of MPI, where typical…
Epilepsy is a neurological disease characterized by recurrent and spontaneous seizures. It affects approximately 50 million people worldwide. In majority of the cases accurate diagnosis of the disease can be made without using any…
Predicting seizure freedom is essential for tailoring epilepsy treatment. But accurate prediction remains challenging with traditional methods, especially with diverse patient populations. This study developed a deep learning-based graph…
Epilepsy is a prevalent neurological disorder affecting 50 million individuals worldwide and 1.2 million Americans. There exist millions of pediatric patients with intractable epilepsy, a condition in which seizures fail to come under…
During the last three decades, many studies have been conducted in the field of treatment with non-invasive methods. In this way, researchers try to use alternative methods including the use of electromagnetic waves in the treatment of…
Information transmission in the human brain is a fundamentally dynamic network process. In partial epilepsy, this process is perturbed and highly synchronous seizures originate in a local network, the so-called epileptogenic zone (EZ),…