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We study the benign overfitting theory in the prediction of the conditional average treatment effect (CATE), with linear regression models. As the development of machine learning for causal inference, a wide range of large-scale models for…

Econometrics · Economics 2022-02-17 Masahiro Kato , Masaaki Imaizumi

This article proposes a meta-learning method for estimating the conditional average treatment effect (CATE) from a few observational data. The proposed method learns how to estimate CATEs from multiple tasks and uses the knowledge for…

Machine Learning · Statistics 2023-05-22 Tomoharu Iwata , Yoichi Chikahara

Estimating personalized treatment effects from high-dimensional observational data is essential in situations where experimental designs are infeasible, unethical, or expensive. Existing approaches rely on fitting deep models on outcomes…

Machine Learning · Computer Science 2022-02-02 Andrew Jesson , Panagiotis Tigas , Joost van Amersfoort , Andreas Kirsch , Uri Shalit , Yarin Gal

In computed tomography (CT), achieving high image quality while minimizing radiation exposure remains a key clinical challenge. This paper presents CAPRI-CT, a novel causal-aware deep learning framework for Causal Analysis and Predictive…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Sneha George Gnanakalavathy , Hairil Abdul Razak , Robert Meertens , Jonathan E. Fieldsend , Xujiong Ye , Mohammed M. Abdelsamea

Advances in digitizing tissue slides and the fast-paced progress in artificial intelligence, including deep learning, have boosted the field of computational pathology. This field holds tremendous potential to automate clinical diagnosis,…

Image and Video Processing · Electrical Eng. & Systems 2024-01-17 Andrew H. Song , Guillaume Jaume , Drew F. K. Williamson , Ming Y. Lu , Anurag Vaidya , Tiffany R. Miller , Faisal Mahmood

Diagnosis based on medical images, such as X-ray images, often involves manual annotation of anatomical keypoints. However, this process involves significant human efforts and can thus be a bottleneck in the diagnostic process. To fully…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Jinhee Kim , Taesung Kim , Taewoo Kim , Jaegul Choo , Dong-Wook Kim , Byungduk Ahn , In-Seok Song , Yoon-Ji Kim

The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods. In this paper, we propose MDNet to establish a direct multimodal…

Computer Vision and Pattern Recognition · Computer Science 2017-07-11 Zizhao Zhang , Yuanpu Xie , Fuyong Xing , Mason McGough , Lin Yang

Motivation. Cancer heterogeneity is observed at multiple biological levels. To improve our understanding of these differences and their relevance in medicine, approaches to link organ- and tissue-level information from diagnostic images and…

Quantitative Methods · Quantitative Biology 2020-05-19 Nova F. Smedley , Suzie El-Saden , William Hsu

An important task in drug development is to identify patients, which respond better or worse to an experimental treatment. Identifying predictive covariates, which influence the treatment effect and can be used to define subgroups of…

Methodology · Statistics 2018-11-27 Marius Thomas , Björn Bornkamp , Katja Ickstadt

Detection of interactions between treatment effects and patient descriptors in clinical trials is critical for optimizing the drug development process. The increasing volume of data accumulated in clinical trials provides a unique…

Applications · Statistics 2017-12-25 Baptiste Goujaud , Eric W. Tramel , Pierre Courtiol , Mikhail Zaslavskiy , Gilles Wainrib

The COVID-19 pandemic has left a lasting impact on individuals, with many experiencing persistent symptoms, including inflammation, in the post-acute phase of the disease. Detecting and monitoring these inflammatory biomarkers is critical…

Machine Learning · Computer Science 2023-09-28 Ghizal Fatima , Fadhil G. Al-Amran , Maitham G. Yousif

Background: In medical imaging, images are usually treated as deterministic, while their uncertainties are largely underexplored. Purpose: This work aims at using deep learning to efficiently estimate posterior distributions of imaging…

Image and Video Processing · Electrical Eng. & Systems 2023-03-20 Xiaofeng Liu , Thibault Marin , Tiss Amal , Jonghye Woo , Georges El Fakhri , Jinsong Ouyang

The integration of artificial intelligence [AI] into clinical trials has revolutionized the process of drug development and personalized medicine. Among these advancements, deep learning and predictive modelling have emerged as…

Machine Learning · Computer Science 2024-12-11 Sydney Anuyah , Mallika K Singh , Hope Nyavor

Matching in causal inference from observational data aims to construct treatment and control groups with similar distributions of covariates, thereby reducing confounding and ensuring an unbiased estimation of treatment effects. This…

Artificial Intelligence · Computer Science 2025-04-15 Sahil Shikalgar , Md. Noor-E-Alam

The need for a large amount of labeled data in the supervised setting has led recent studies to utilize self-supervised learning to pre-train deep neural networks using unlabeled data. Many self-supervised training strategies have been…

Computer Vision and Pattern Recognition · Computer Science 2022-04-06 Mojtaba Bahrami , Mahsa Ghorbani , Nassir Navab

We consider machine-learning-based malignancy prediction and lesion identification from clinical dermatological images, which can be indistinctly acquired via smartphone or dermoscopy capture. Additionally, we do not assume that images…

Computer Vision and Pattern Recognition · Computer Science 2021-04-07 Meng Xia , Meenal K. Kheterpal , Samantha C. Wong , Christine Park , William Ratliff , Lawrence Carin , Ricardo Henao

This study presents a systematic machine-learning approach for classifying acute pain from raw electrophysiological signals. We address binary and ternary classification tasks, leveraging Power-In-Band (PIB) and signal coherence as…

Signal Processing · Electrical Eng. & Systems 2025-03-06 Sidharth Sidharth , Vishwas Sathish , Shweta Bansal , Samantha Sun , Timmy Pham , Kurt Weaver , Rajesh P. N. Rao , Jeffrey Herron

Medical imaging plays a vital role in modern diagnostics; however, interpreting high-resolution radiological data remains time-consuming and susceptible to variability among clinicians. Traditional image processing techniques often lack the…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Melika Filvantorkaman , Maral Filvan Torkaman

This paper presents a novel positive and negative set selection strategy for contrastive learning of medical images based on labels that can be extracted from clinical data. In the medical field, there exists a variety of labels for data…

Computer Vision and Pattern Recognition · Computer Science 2023-05-25 Kiran Kokilepersaud , Stephanie Trejo Corona , Mohit Prabhushankar , Ghassan AlRegib , Charles Wykoff

Reliable estimation of treatment effects from observational data is important in many disciplines such as medicine. However, estimation is challenging when unconfoundedness as a standard assumption in the causal inference literature is…

Machine Learning · Computer Science 2024-10-15 Jonas Schweisthal , Dennis Frauen , Maresa Schröder , Konstantin Hess , Niki Kilbertus , Stefan Feuerriegel