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Despite the ever-increasing interest in applying deep learning (DL) models to medical imaging, the typical scarcity and imbalance of medical datasets can severely impact the performance of DL models. The generation of synthetic data that…

Image and Video Processing · Electrical Eng. & Systems 2023-04-03 Pouria Rouzrokh , Bardia Khosravi , Shahriar Faghani , Mana Moassefi , Sanaz Vahdati , Bradley J. Erickson

Pseudo-healthy image inpainting is an essential preprocessing step for analyzing pathological brain MRI scans. Most current inpainting methods favor slice-wise 2D models for their high in-plane fidelity, but their independence across slices…

Image and Video Processing · Electrical Eng. & Systems 2025-07-25 Dou Hoon Kwark , Shirui Luo , Xiyue Zhu , Yudu Li , Zhi-Pei Liang , Volodymyr Kindratenko

In multiple sclerosis, lesions interfere with automated magnetic resonance imaging analyses such as brain parcellation and deformable registration, while lesion segmentation models are hindered by the limited availability of annotated…

Accurate longitudinal analysis of brain MRI is often hindered by evolving lesions, which bias automated neuroimaging pipelines. While deep generative models have shown promise in inpainting these lesions, most existing methods operate…

Image and Video Processing · Electrical Eng. & Systems 2026-03-09 Zahra Karimaghaloo , Dumitru Fetco , Haz-Edine Assemlal , Hassan Rivaz , Douglas L. Arnold

Collecting pixel-level labels for medical datasets can be a laborious and expensive process, and enhancing segmentation performance with a scarcity of labeled data is a crucial challenge. This work introduces AugPaint, a data augmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Xinrong Hu , Yiyu Shi

Synthesizing healthy brain scans from diseased brain scans offers a potential solution to address the limitations of general-purpose algorithms, such as tissue segmentation and brain extraction algorithms, which may not effectively handle…

Image and Video Processing · Electrical Eng. & Systems 2024-02-05 Ruizhi Zhu , Xinru Zhang , Haowen Pang , Chundan Xu , Chuyang Ye

Medical imaging datasets often suffer from class imbalance and limited availability of pathology-rich cases, which constrains the performance of machine learning models for segmentation, classification, and vision-language tasks. To address…

Image and Video Processing · Electrical Eng. & Systems 2026-01-15 Fei Tan , Ashok Vardhan Addala , Bruno Astuto Arouche Nunes , Xucheng Zhu , Ravi Soni

Image inpainting is the task of reconstructing missing or damaged parts of an image in a way that seamlessly blends with the surrounding content. With the advent of advanced generative models, especially diffusion models and generative…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Xingzhong Hou , Jie Wu , Boxiao Liu , Yi Zhang , Guanglu Song , Yunpeng Liu , Yu Liu , Haihang You

Diffusion probabilistic models learn to remove noise added during training, generating novel data (e.g., images) from Gaussian noise through sequential denoising. However, conditioning the generative process on corrupted or masked images is…

Computer Vision and Pattern Recognition · Computer Science 2026-05-01 Sakshi Agarwal , Gabriel Hope , Jimin Heo , Erik B. Sudderth

Purpose: In the present work we describe the correction of diffusion-weighted MRI for site and scanner biases using a novel method based on invariant representation. Theory and Methods: Pooled imaging data from multiple sources are subject…

Quantitative Methods · Quantitative Biology 2020-02-04 Daniel Moyer , Greg Ver Steeg , Chantal M. W. Tax , Paul M. Thompson

Implicit Neural Representations (INRs) are a learning-based approach to accelerate Magnetic Resonance Imaging (MRI) acquisitions, particularly in scan-specific settings when only data from the under-sampled scan itself are available.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Yamin Arefeen , Brett Levac , Zach Stoebner , Jonathan Tamir

Magnetic Resonance Imaging (MRI) is the primary imaging modality used in the diagnosis, assessment, and treatment planning for brain pathologies. However, most automated MRI analysis tools, such as segmentation and registration pipelines,…

Brain tumors delay the standard preprocessing workflow for further examination. Brain inpainting offers a viable, although difficult, solution for tumor tissue processing, which is necessary to improve the precision of the diagnosis and…

Image and Video Processing · Electrical Eng. & Systems 2025-02-25 Tianli Tao , Ziyang Wang , Han Zhang , Theodoros N. Arvanitis , Le Zhang

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

Monitoring diseases that affect the brain's structural integrity requires automated analysis of magnetic resonance (MR) images, e.g., for the evaluation of volumetric changes. However, many of the evaluation tools are optimized for…

The development of robust artificial intelligence models for histopathology diagnosis is severely constrained by the scarcity of expert-annotated lesion data, particularly for rare pathologies and underrepresented disease subtypes. While…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Mohamad Koohi-Moghadam , Mohammad-Ali Nikouei Mahani , Kyongtae Tyler Bae

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

Despite continued advancement in recent years, deep neural networks still rely on large amounts of training data to avoid overfitting. However, labeled training data for real-world applications such as healthcare is limited and difficult to…

Image synthesis approaches, e.g., generative adversarial networks, have been popular as a form of data augmentation in medical image analysis tasks. It is primarily beneficial to overcome the shortage of publicly accessible data and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Shiyi Du , Xiaosong Wang , Yongyi Lu , Yuyin Zhou , Shaoting Zhang , Alan Yuille , Kang Li , Zongwei Zhou

Diffusion models, as powerful generative models, have found a wide range of applications and shown great potential in solving image reconstruction problems. Some works attempted to solve MRI reconstruction with diffusion models, but these…

Image and Video Processing · Electrical Eng. & Systems 2025-06-09 Xingjian Tang , Jingwei Guan , Linge Li , Ran Shi , Youmei Zhang , Mengye Lyu , Li Yan
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