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Source-free test-time adaptation for medical image segmentation aims to enhance the adaptability of segmentation models to diverse and previously unseen test sets of the target domain, which contributes to the generalizability and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Yanyu Ye , Zhenxi Zhang , Wei Wei , Chunna Tian

We present MaskGen, a theoretically grounded and deliberately simple approach for domain generalization in 3D biomedical image segmentation. Modern segmentation models degrade sharply under shifts in modality, disease severity, clinical…

Image and Video Processing · Electrical Eng. & Systems 2026-05-12 Sebo Diaz , Polina Golland , Elfar Adalsteinsson , Neel Dey

Model generalization capacity at domain shift (e.g., various imaging protocols and scanners) is crucial for deep learning methods in real-world clinical deployment. This paper tackles the challenging problem of domain generalization, i.e.,…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Quande Liu , Qi Dou , Pheng-Ann Heng

Multi-domain data are widely leveraged in vision applications taking advantage of complementary information from different modalities, e.g., brain tumor segmentation from multi-parametric magnetic resonance imaging (MRI). However, due to…

Due to domain shifts across diverse medical imaging modalities, learned segmentation models often suffer significant performance degradation during deployment. We posit that these domain shifts can generally be categorized into two main…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane , Zhaolin Chen

Along with the recent development of deep neural networks, appearance-based gaze estimation has succeeded considerably when training and testing within the same domain. Compared to the within-domain task, the variance of different domains…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Jiawei Qin , Takuru Shimoyama , Xucong Zhang , Yusuke Sugano

Recently, we have witnessed great progress in the field of medical imaging classification by adopting deep neural networks. However, the recent advanced models still require accessing sufficiently large and representative datasets for…

Computer Vision and Pattern Recognition · Computer Science 2020-10-30 Haoliang Li , YuFei Wang , Renjie Wan , Shiqi Wang , Tie-Qiang Li , Alex C. Kot

Feature alignment between domains is one of the mainstream methods for Unsupervised Domain Adaptation (UDA) semantic segmentation. Existing feature alignment methods for semantic segmentation learn domain-invariant features by adversarial…

Computer Vision and Pattern Recognition · Computer Science 2021-05-10 Shuang Wang , Dong Zhao , Yi Li , Chi Zhang , Yuwei Guo , Qi Zang , Biao Hou , Licheng Jiao

Despite domain generalization (DG) has significantly addressed the performance degradation of pre-trained models caused by domain shifts, it often falls short in real-world deployment. Test-time adaptation (TTA), which adjusts a learned…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Xingguo Lv , Xingbo Dong , Liwen Wang , Jiewen Yang , Lei Zhao , Bin Pu , Zhe Jin , Xuejun Li

The domain generalization problem has been widely investigated in deep learning for non-contrast imaging over the last years, but it received limited attention for contrast-enhanced imaging. However, there are marked differences in contrast…

Comprehensive semantic segmentation is one of the key components for robust scene understanding and a requirement to enable autonomous driving. Driven by large scale datasets, convolutional neural networks show impressive results on this…

Computer Vision and Pattern Recognition · Computer Science 2019-08-30 Jan-Nico Zaech , Dengxin Dai , Martin Hahner , Luc Van Gool

An organ segmentation method that can generalize to unseen contrasts and scanner settings can significantly reduce the need for retraining of deep learning models. Domain Generalization (DG) aims to achieve this goal. However, most DG…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yanwu Xu , Shaoan Xie , Maxwell Reynolds , Matthew Ragoza , Mingming Gong , Kayhan Batmanghelich

Deep learning based methods often suffer from performance degradation caused by domain shift. In recent years, many sophisticated network structures have been designed to tackle this problem. However, the advent of large model trained on…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Zhikai Wei , Wenhui Dong , Peilin Zhou , Yuliang Gu , Zhou Zhao , Yongchao Xu

Deep learning models obtain impressive accuracy in road scenes understanding, however they need a large quantity of labeled samples for their training. Additionally, such models do not generalise well to environments where the statistical…

Computer Vision and Pattern Recognition · Computer Science 2021-10-28 Francesco Barbato , Umberto Michieli , Marco Toldo , Pietro Zanuttigh

Deep neural networks (DNN) have demonstrated unprecedented success for medical imaging applications. However, due to the issue of limited dataset availability and the strict legal and ethical requirements for patient privacy protection, the…

Machine Learning · Computer Science 2023-09-19 Chris Xing Tian , Haoliang Li , Yufei Wang , Shiqi Wang

The recent progress in text-to-image models pretrained on large-scale datasets has enabled us to generate various images as long as we provide a text prompt describing what we want. Nevertheless, the availability of these models is still…

Computer Vision and Pattern Recognition · Computer Science 2024-11-08 Yuxuan Duan , Yan Hong , Bo Zhang , Jun Lan , Huijia Zhu , Weiqiang Wang , Jianfu Zhang , Li Niu , Liqing Zhang

Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…

Image and Video Processing · Electrical Eng. & Systems 2023-08-09 Sebastian Nørgaard Llambias , Mads Nielsen , Mostafa Mehdipour Ghazi

Domain generalization aims to develop models that are robust to distribution shifts. Existing methods focus on learning invariance across domains to enhance model robustness, and data augmentation has been widely used to learn invariant…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Yingnan Liu , Yingtian Zou , Rui Qiao , Fusheng Liu , Mong Li Lee , Wynne Hsu

Clinical machine learning models experience significantly degraded performance in datasets not seen during training, e.g., new hospitals or populations. Recent developments in domain generalization offer a promising solution to this problem…

Machine Learning · Computer Science 2021-04-16 Haoran Zhang , Natalie Dullerud , Laleh Seyyed-Kalantari , Quaid Morris , Shalmali Joshi , Marzyeh Ghassemi

In open-world scenarios, where both novel classes and domains may exist, an ideal segmentation model should detect anomaly classes for safety and generalize to new domains. However, existing methods often struggle to distinguish between…

Computer Vision and Pattern Recognition · Computer Science 2024-11-07 Zhitong Gao , Bingnan Li , Mathieu Salzmann , Xuming He