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We consider distributions arising from a mixture of causal models, where each model is represented by a directed acyclic graph (DAG). We provide a graphical representation of such mixture distributions and prove that this representation…

Machine Learning · Statistics 2020-08-11 Basil Saeed , Snigdha Panigrahi , Caroline Uhler

Causal discovery, the task of inferring causal structure from data, has the potential to uncover mechanistic insights from biological experiments, especially those involving perturbations. However, causal discovery algorithms over larger…

Machine Learning · Computer Science 2025-04-01 Menghua Wu , Yujia Bao , Regina Barzilay , Tommi Jaakkola

Constraint-based causal discovery methods leverage conditional independence tests to infer causal relationships in a wide variety of applications. Just as the majority of machine learning methods, existing work focuses on studying…

Machine Learning · Statistics 2024-05-27 Siyuan Guo , Viktor Tóth , Bernhard Schölkopf , Ferenc Huszár

If $X,Y,Z$ denote sets of random variables, two different data sources may contain samples from $P_{X,Y}$ and $P_{Y,Z}$, respectively. We argue that causal discovery can help inferring properties of the `unobserved joint distributions'…

Machine Learning · Statistics 2023-05-12 Dominik Janzing , Philipp M. Faller , Leena Chennuru Vankadara

We consider the problem of learning causal networks with interventions, when each intervention is limited in size under Pearl's Structural Equation Model with independent errors (SEM-IE). The objective is to minimize the number of…

Artificial Intelligence · Computer Science 2015-11-03 Karthikeyan Shanmugam , Murat Kocaoglu , Alexandros G. Dimakis , Sriram Vishwanath

Biomarker discovery from high-throughput transcriptomic data is crucial for advancing precision medicine. However, existing methods often neglect gene-gene regulatory relationships and lack stability across datasets, leading to conflation…

Quantitative Methods · Quantitative Biology 2025-11-18 Chaowang Lan , Jingxin Wu , Yulong Yuan , Chuxun Liu , Huangyi Kang , Caihua Liu

Causal graphs (CGs) are compact representations of the knowledge of the data generating processes behind the data distributions. When a CG is available, e.g., from the domain knowledge, we can infer the conditional independence (CI)…

Machine Learning · Computer Science 2021-08-18 Takeshi Teshima , Masashi Sugiyama

Missing data are ubiquitous in many domains including healthcare. When these data entries are not missing completely at random, the (conditional) independence relations in the observed data may be different from those in the complete data…

Machine Learning · Computer Science 2020-07-14 Ruibo Tu , Kun Zhang , Paul Ackermann , Bo Christer Bertilson , Clark Glymour , Hedvig Kjellström , Cheng Zhang

Causality is receiving increasing attention by the artificial intelligence and machine learning communities. This paper gives an example of modelling a recommender system problem using causal graphs. Specifically, we approached the causal…

Information Retrieval · Computer Science 2024-09-17 Emanuele Cavenaghi , Fabio Stella , Markus Zanker

Testing for conditional independence is a core aspect of constraint-based causal discovery. Although commonly used tests are perfect in theory, they often fail to reject independence in practice, especially when conditioning on multiple…

Machine Learning · Statistics 2019-03-13 Alexander Marx , Jilles Vreeken

Directed acyclic graphs have been used fruitfully to represent causal strucures (Pearl 1988). However, in the social sciences and elsewhere models are often used which correspond both causally and statistically to directed graphs with…

Artificial Intelligence · Computer Science 2020-10-24 Thomas S. Richardson

Learning DAG structures from purely observational data remains a long-standing challenge across scientific domains. An emerging line of research leverages the score of the data distribution to initially identify a topological order of the…

Machine Learning · Computer Science 2026-01-27 Vy Vo , He Zhao , Trung Le , Edwin V. Bonilla , Dinh Phung

Causal structure learning from observational data remains a non-trivial task due to various factors such as finite sampling, unobserved confounding factors, and measurement errors. Constraint-based and score-based methods tend to suffer…

Machine Learning · Computer Science 2022-11-09 Rezaur Rashid , Jawad Chowdhury , Gabriel Terejanu

The PC algorithm uses conditional independence tests for model selection in graphical modeling with acyclic directed graphs. In Gaussian models, tests of conditional independence are typically based on Pearson correlations, and…

Statistics Theory · Mathematics 2012-07-03 Naftali Harris , Mathias Drton

In recent years, causal modelling has been used widely to improve generalization and to provide interpretability in machine learning models. To determine cause-effect relationships in the absence of a randomized trial, we can model causal…

Machine Learning · Computer Science 2021-06-03 Rohan Giriraj , Sinnu Susan Thomas

As causal ground truth is incredibly rare, causal discovery algorithms are commonly only evaluated on simulated data. This is concerning, given that simulations reflect preconceptions about generating processes regarding noise…

Neural networks have proven to be effective at solving machine learning tasks but it is unclear whether they learn any relevant causal relationships, while their black-box nature makes it difficult for modellers to understand and debug…

Machine Learning · Computer Science 2023-08-02 Fabrizio Russo , Francesca Toni

Causal interactions among a group of variables are often modeled by a single causal graph. In some domains, however, these interactions are best described by multiple co-existing causal graphs, e.g., in dynamical systems or genomics. This…

Machine Learning · Computer Science 2024-12-04 Burak Varıcı , Dmitriy Katz-Rogozhnikov , Dennis Wei , Prasanna Sattigeri , Ali Tajer

Causal opacity denotes the difficulty in understanding the "hidden" causal structure underlying the decisions of deep neural network (DNN) models. This leads to the inability to rely on and verify state-of-the-art DNN-based systems,…

Controlling false positives (Type I errors) through statistical hypothesis testing is a foundation of modern scientific data analysis. Existing causal structure discovery algorithms either do not provide Type I error control or cannot scale…

Methodology · Statistics 2025-12-29 James Leiner , Brian Manzo , Aaditya Ramdas , Wesley Tansey
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