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We apply a hybrid evolutionary algorithm to minimize the depth of circuits in quantum computing. More specifically, we evaluate two different variants of the algorithm. In the first approach, we combine the evolutionary algorithm with an…

Accurate prediction of mRNA secondary structure is critical for understanding gene expression, translation efficiency, and advancing mRNA-based therapeutics. However, the combinatorial complexity of possible foldings, especially in long…

Quantum computers allow a near-exponential speed-up for specific applications when compared to classical computers. Despite recent advances in the hardware of quantum computers, their practical usage is still severely limited due to a…

Quantum Physics · Physics 2025-05-09 Tobias Fischbach , Pierre Talbot , Pascal Bouvry

Diagnosing the minimal set of faults capable of explaining a set of given observations, e.g., from sensor readouts, is a hard combinatorial optimization problem usually tackled with artificial intelligence techniques. We present the mapping…

We introduce an optimisation method for variational quantum algorithms and experimentally demonstrate a 100-fold improvement in efficiency compared to naive implementations. The effectiveness of our approach is shown by obtaining…

We present an end-to-end pipeline for large-scale portfolio selection with cardinality constraints and experimentally demonstrate it on trapped-ion quantum processors using hardware-aware decomposition. Building on RMT-based…

Variational quantum algorithms are the centerpiece of modern quantum programming. These algorithms involve training parameterized quantum circuits using a classical co-processor, an approach adapted partly from classical machine learning.…

Quantum Physics · Physics 2022-11-09 V. Akshay , H. Philathong , E. Campos , D. Rabinovich , I. Zacharov , Xiao-Ming Zhang , J. Biamonte

Quantum computing is an emerging technology in which quantum mechanical properties are suitably utilized to perform certain compute-intensive operations faster than classical computers. Quantum algorithms are designed as a combination of…

Emerging Technologies · Computer Science 2023-06-06 Aravind Joshi , Akshara Kairali , Renju Raju , Adithya Athreya , Reena Monica P , Sanjay Vishwakarma , Srinjoy Ganguly

We develop a hardware-efficient ansatz for variational optimization, derived from existing ansatze in the literature, that parametrizes subsets of all interactions in the Cost Hamiltonian in each layer. We treat gate orderings as a…

This paper investigates the application of quantum computing technology to airline gate-scheduling quadratic assignment problems (QAP). We explore the quantum computing hardware architecture and software environment required for porting…

Quadratic Unconstrained Binary Optimization (QUBO) provides a versatile framework for representing NP-hard combinatorial problems, yet existing solvers often face trade-offs among speed, accuracy, and scalability. In this work, we introduce…

Quantum Physics · Physics 2025-06-06 Jiecheng Yang , Ding Wang , Xiang Zhao , Hairui Zhang , Ming Gao , Lin Yang

The Quadratic Unconstrained Binary Optimization problem (QUBO) has become a unifying model for representing a wide range of combinatorial optimization problems, and for linking a variety of disciplines that face these problems. A new class…

Artificial Intelligence · Computer Science 2017-05-30 Mark Lewis , Fred Glover

Variational quantum eigensolver (VQE) is regarded as a promising candidate of hybrid quantum-classical algorithm for the near-term quantum computers. Meanwhile, VQE is confronted with a challenge that statistical error associated with the…

Quantum Physics · Physics 2023-12-12 Ken N. Okada , Keita Osaki , Kosuke Mitarai , Keisuke Fujii

Variational quantum algorithms are a class of techniques intended to be used on near-term quantum computers. The goal of these algorithms is to perform large quantum computations by breaking the problem down into a large number of shallow…

Quantum Physics · Physics 2023-03-24 Ryan Shaffer , Lucas Kocia , Mohan Sarovar

Performing experiments on small-scale quantum computers is certainly a challenging endeavor. Many parameters need to be optimized to achieve high-fidelity operations. This can be done efficiently for operations acting on single qubits as…

Quantum Physics · Physics 2016-08-31 M. Müller , A. Rivas , E. A. Martínez , D. Nigg , P. Schindler , T. Monz , R. Blatt , M. A. Martin-Delgado

We introduce parity quantum optimization with the aim of solving optimization problems consisting of arbitrary $k$-body interactions and side conditions using planar quantum chip architectures. The method introduces a decomposition of the…

Solving real-world optimization problems with quantum computing requires choosing between a large number of options concerning formulation, encoding, algorithm and hardware. Finding good solution paths is challenging for end users and…

This paper proposes a hybrid quantum-classical algorithm that learns a suitable quantum feature map that separates unlabelled data that is originally non linearly separable in the classical space using a Variational quantum feature map and…

Quantum Physics · Physics 2021-12-14 Arvind S Menon , Nikaash Puri

We consider the problem of the variational quantum circuit synthesis into a gate set consisting of the CNOT gate and arbitrary single-qubit (1q) gates with the primary target being the minimization of the CNOT count. First we note that…

Quantum Physics · Physics 2023-05-10 Nikita A. Nemkov , Evgeniy O. Kiktenko , Ilia A. Luchnikov , Aleksey K. Fedorov

Solving combinatorial optimization problems on current noisy quantum devices is currently being advocated for (and restricted to) binary polynomial optimization with equality constraints via quantum heuristic approaches. This is achieved…

Quantum Physics · Physics 2021-02-04 Claudio Gambella , Andrea Simonetto
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