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Purpose: The performance of three different large language models (LLMS) (GPT-3.5, GPT-4, and PaLM2) in answering ophthalmology professional questions was evaluated and compared with that of three different professional populations (medical…

Computation and Language · Computer Science 2023-11-10 Jason Holmes , Shuyuan Ye , Yiwei Li , Shi-Nan Wu , Zhengliang Liu , Zihao Wu , Jinyu Hu , Huan Zhao , Xi Jiang , Wei Liu , Hong Wei , Jie Zou , Tianming Liu , Yi Shao

Phenotype-driven gene prioritization is a critical process in the diagnosis of rare genetic disorders for identifying and ranking potential disease-causing genes based on observed physical traits or phenotypes. While traditional approaches…

Quantitative Methods · Quantitative Biology 2024-04-04 Junyoung Kim , Jingye Yang , Kai Wang , Chunhua Weng , Cong Liu

Intermediate Representations (IRs) play a critical role in compiler design and program analysis, yet their comprehension by Large Language Models (LLMs) remains underexplored. In this paper, we present an explorative empirical study…

Machine Learning · Computer Science 2025-06-06 Hailong Jiang , Jianfeng Zhu , Yao Wan , Bo Fang , Hongyu Zhang , Ruoming Jin , Qiang Guan

Multimodal Large Language Models (MLLMs) promise advanced vision language capabilities, yet their effectiveness in visually presented mathematics remains underexplored. This paper analyzes the development and evaluation of MLLMs for…

Automated fact-checking, using machine learning to verify claims, has grown vital as misinformation spreads beyond human fact-checking capacity. Large Language Models (LLMs) like GPT-4 are increasingly trusted to write academic papers,…

Computation and Language · Computer Science 2024-02-08 Dorian Quelle , Alexandre Bovet

The rapid advancement of Large Language Models (LLMs) presents a significant challenge to academic integrity within computing education. As educators seek reliable detection methods, this paper evaluates the capacity of three prominent LLMs…

Computers and Society · Computer Science 2025-12-30 Christopher Burger , Karmece Talley , Christina Trotter

Prompting techniques have significantly enhanced the capabilities of Large Language Models (LLMs) across various complex tasks, including reasoning, planning, and solving math word problems. However, most research has predominantly focused…

Computation and Language · Computer Science 2024-05-24 Neisarg Dave , Daniel Kifer , C. Lee Giles , Ankur Mali

Large language models (LLMs) have shown considerable promise in clinical natural language processing, yet few domain-specific datasets exist to rigorously evaluate their performance on radiology tasks. In this work, we introduce an…

Computation and Language · Computer Science 2025-11-18 Namu Park , Giridhar Kaushik Ramachandran , Kevin Lybarger , Fei Xia , Ozlem Uzuner , Meliha Yetisgen , Martin Gunn

Large language models (LLMs), such as GPT-3 and GPT-4, have demonstrated exceptional performance in various natural language processing tasks and have shown the ability to solve certain reasoning problems. However, their reasoning…

Artificial Intelligence · Computer Science 2023-07-18 Adam Ishay , Zhun Yang , Joohyung Lee

Various deep learning-based approaches utilizing pre-trained language models (PLMs) have been proposed for automated vulnerability detection. With recent advancements in large language models (LLMs), several studies have begun exploring…

Software Engineering · Computer Science 2026-03-11 Honglin Shu , Michael Fu , Junji Yu , Dong Wang , Chakkrit Tantithamthavorn , Junjie Chen , Yasutaka Kamei

The widespread adoption of large language models (LLMs) makes it important to recognize their strengths and limitations. We argue that in order to develop a holistic understanding of these systems we need to consider the problem that they…

Computation and Language · Computer Science 2023-09-26 R. Thomas McCoy , Shunyu Yao , Dan Friedman , Matthew Hardy , Thomas L. Griffiths

Machine learning has revolutionized polymer science by enabling rapid property prediction and generative design. Large language models (LLMs) offer further opportunities in polymer informatics by simplifying workflows that traditionally…

Computational Engineering, Finance, and Science · Computer Science 2026-02-20 Sonakshi Gupta , Akhlak Mahmood , Shivank Shukla , Rampi Ramprasad

Large Language Models (LLMs) are trained on massive amounts of data, enabling their application across diverse domains and tasks. Despite their remarkable performance, most LLMs are developed and evaluated primarily in English. Recently, a…

Computation and Language · Computer Science 2024-10-18 Krishno Dey , Prerona Tarannum , Md. Arid Hasan , Imran Razzak , Usman Naseem

Despite their success in many natural language tasks, solving math problems remains a significant challenge for large language models (LLMs). A large gap exists between LLMs' pass-at-one and pass-at-N performance in solving math problems,…

Computation and Language · Computer Science 2023-10-17 Yixin Liu , Avi Singh , C. Daniel Freeman , John D. Co-Reyes , Peter J. Liu

Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

Large Language Models (LLMs) generate responses to questions; however, their effectiveness is often hindered by sub-optimal quality of answers and occasional failures to provide accurate responses to questions. To address these challenges,…

Computation and Language · Computer Science 2024-02-06 Liang Zhang , Katherine Jijo , Spurthi Setty , Eden Chung , Fatima Javid , Natan Vidra , Tommy Clifford

Mathematical reasoning remains a challenging area for large language models (LLMs), prompting the development of math-specific LLMs such as LLEMMA, DeepSeekMath, and Qwen2-Math, among others. These models typically follow a two-stage…

Computation and Language · Computer Science 2025-03-25 Zui Chen , Tianqiao Liu , Mi Tian , Qing Tong , Weiqi Luo , Zitao Liu

Thinking Large Language Models (LLMs) generate explicit intermediate reasoning traces before final answers, potentially improving transparency, interpretability, and solution accuracy for code generation. However, the quality of these…

Artificial Intelligence · Computer Science 2025-11-11 Haoran Xue , Gias Uddin , Song Wang

Large Language Models (LLMs) are transformer-based machine learning models that have shown remarkable performance in tasks for which they were not explicitly trained. Here, we explore the potential of LLMs to perform symbolic regression --…

Computation and Language · Computer Science 2026-04-17 Samiha Sharlin , Tyler R. Josephson

Large language models (LLMs) have achieved impressive performance across various mathematical reasoning benchmarks. However, there are increasing debates regarding whether these models truly understand and apply mathematical knowledge or…

Computation and Language · Computer Science 2024-07-03 Qintong Li , Leyang Cui , Xueliang Zhao , Lingpeng Kong , Wei Bi