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Deep learning methods such as convolutional neural networks (CNNs) are difficult to directly utilize to analyze whole slide images (WSIs) due to the large image dimensions. We overcome this limitation by proposing a novel two-stage…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Shivam Kalra , Mohammed Adnan , Sobhan Hemati , Taher Dehkharghanian , Shahryar Rahnamayan , Hamid Tizhoosh

With the popularity of foundational models, parameter efficient fine tuning has become the defacto approach to leverage pretrained models to perform downstream tasks. Taking inspiration from recent advances in large language models, Visual…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Aadya Arora , Vinay Namboodiri

The Multiple Instance Learning (MIL) paradigm is attracting plenty of attention in medical imaging classification, where labeled data is scarce. MIL methods cast medical images as bags of instances (e.g. patches in whole slide images, or…

Computer Vision and Pattern Recognition · Computer Science 2025-07-22 Francisco M. Castro-Macías , Pablo Morales-Álvarez , Yunan Wu , Rafael Molina , Aggelos K. Katsaggelos

Contrastive Language Image Pre-training (CLIP) has recently demonstrated success across various tasks due to superior feature representation empowered by image-text contrastive learning. However, the instance discrimination method used by…

Computer Vision and Pattern Recognition · Computer Science 2024-11-07 Xiang An , Kaicheng Yang , Xiangzi Dai , Ziyong Feng , Jiankang Deng

We develop a transductive meta-learning method that uses unlabelled instances to improve few-shot image classification performance. Our approach combines a regularized Mahalanobis-distance-based soft k-means clustering procedure with a…

Computer Vision and Pattern Recognition · Computer Science 2021-10-22 Peyman Bateni , Jarred Barber , Jan-Willem van de Meent , Frank Wood

While multiple instance learning (MIL) has shown to be a promising approach for histopathological whole slide image (WSI) analysis, its reliance on permutation invariance significantly limits its capacity to effectively uncover semantic…

Image and Video Processing · Electrical Eng. & Systems 2025-07-14 Xiwen Chen , Peijie Qiu , Wenhui Zhu , Hao Wang , Huayu Li , Xuanzhao Dong , Xiaotong Sun , Xiaobing Yu , Yalin Wang , Abolfazl Razi , Aristeidis Sotiras

Most multi-view clustering methods are limited by shallow models without sound nonlinear information perception capability, or fail to effectively exploit complementary information hidden in different views. To tackle these issues, we…

Machine Learning · Computer Science 2022-10-14 Fu Lele , Zhang Lei , Yang Jinghua , Chen Chuan , Zhang Chuanfu , Zheng Zibin

Hierarchical clustering recursively partitions data at an increasingly finer granularity. In real-world applications, multi-view data have become increasingly important. This raises a less investigated problem, i.e., multi-view hierarchical…

Machine Learning · Computer Science 2022-05-06 Fangfei Lin , Bing Bai , Kun Bai , Yazhou Ren , Peng Zhao , Zenglin Xu

An intrinsic problem of classifiers based on machine learning (ML) methods is that their learning time grows as the size and complexity of the training dataset increases. For this reason, it is important to have efficient computational…

Machine Learning · Computer Science 2013-04-16 Khadoudja Ghanem

Multiple Instance Learning (MIL) is the predominant framework for classifying gigapixel whole-slide images in computational pathology. MIL follows a sequence of 1) extracting patch features, 2) applying a linear layer to obtain…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Daniel Shao , Joel Runevic , Richard J. Chen , Drew F. K. Williamson , Ahrong Kim , Andrew H. Song , Faisal Mahmood

Digital pathology has revolutionized the field by enabling the digitization of tissue samples into whole slide images (WSIs). However, the high resolution and large size of WSIs present significant challenges when it comes to applying Deep…

Computer Vision and Pattern Recognition · Computer Science 2025-07-03 Ali Mammadov , Loïc Le Folgoc , Guillaume Hocquet , Pietro Gori

Fine-tuning is widely applied in image classification tasks as a transfer learning approach. It re-uses the knowledge from a source task to learn and obtain a high performance in target tasks. Fine-tuning is able to alleviate the challenge…

Computer Vision and Pattern Recognition · Computer Science 2022-07-27 Xuyang Shen , Jo Plested , Sabrina Caldwell , Yiran Zhong , Tom Gedeon

Multimodal federated learning enables privacy-preserving collaborative model training across healthcare institutions. However, a fundamental challenge arises from modality heterogeneity: many clinical sites possess only a subset of…

Image and Video Processing · Electrical Eng. & Systems 2026-04-15 Nafis Fuad Shahid , Maroof Ahmed , Md Akib Haider , Saidur Rahman Sagor , Aashnan Rahman , Md Azam Hossain

We present a general methodology that learns to classify images without labels by leveraging pretrained feature extractors. Our approach involves self-distillation training of clustering heads based on the fact that nearest neighbours in…

Computer Vision and Pattern Recognition · Computer Science 2023-11-13 Nikolas Adaloglou , Felix Michels , Hamza Kalisch , Markus Kollmann

Multiple Instance Learning (MIL) is a popular weakly-supervised method for various applications, with a particular interest in histological whole slide image (WSI) classification. Due to the gigapixel resolution of WSI, applications of MIL…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Wenhui Zhu , Peijie Qiu , Xiwen Chen , Zhangsihao Yang , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

Deep learning technology has enabled successful modeling of complex facial features when high quality images are available. Nonetheless, accurate modeling and recognition of human faces in real world scenarios `on the wild' or under adverse…

Computer Vision and Pattern Recognition · Computer Science 2020-11-30 S. W. Arachchilage , E. Izquierdo

Whole Slide Images (WSIs) present a challenging computer vision task due to their gigapixel size and presence of numerous artefacts. Yet they are a valuable resource for patient diagnosis and stratification, often representing the gold…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Amaya Gallagher-Syed , Luca Rossi , Felice Rivellese , Costantino Pitzalis , Myles Lewis , Michael Barnes , Gregory Slabaugh

The popular use of histopathology images, such as hematoxylin and eosin (H&E), has proven to be useful in detecting tumors. However, moving such cancer cases forward for treatment requires accurate on the amount of the human epidermal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Olaide N. Oyelade , Oliver Hoxey , Yulia Humrye

Recent advancements in Contrastive Language-Image Pre-training (CLIP) have demonstrated notable success in self-supervised representation learning across various tasks. However, the existing CLIP-like approaches often demand extensive GPU…

Computer Vision and Pattern Recognition · Computer Science 2024-07-31 Yuexi Du , Brian Chang , Nicha C. Dvornek

Incomplete multi-view unsupervised feature selection (IMUFS), which aims to identify representative features from unlabeled multi-view data containing missing values, has received growing attention in recent years. Despite their promising…

Machine Learning · Computer Science 2025-11-18 Zongxin Shen , Yanyong Huang , Dongjie Wang , Jinyuan Chang , Fengmao Lv , Tianrui Li , Xiaoyi Jiang