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Uncertainty is a fundamental challenge in medical practice, but current medical AI systems fail to explicitly quantify or communicate uncertainty in a way that aligns with clinical reasoning. Existing XAI works focus on interpreting model…

Artificial Intelligence · Computer Science 2025-09-24 Xiuyi Fan

With the advancement of technology for artificial intelligence (AI) based solutions and analytics compute engines, machine learning (ML) models are getting more complex day by day. Most of these models are generally used as a black box…

Machine Learning · Computer Science 2022-10-11 P. Sai Ram Aditya , Mayukha Pal

Individualized treatment rules (ITRs) for treatment recommendation is an important topic for precision medicine as not all beneficial treatments work well for all individuals. Interpretability is a desirable property of ITRs, as it helps…

Methodology · Statistics 2023-11-06 Jacob M. Maronge , Jared D. Huling , Guanhua Chen

Interpretability has become incredibly important as machine learning is increasingly used to inform consequential decisions. We propose to construct global explanations of complex, blackbox models in the form of a decision tree…

Machine Learning · Computer Science 2019-01-28 Osbert Bastani , Carolyn Kim , Hamsa Bastani

Deep neural networks for medical image classification often fail to generalize consistently in clinical practice due to violations of the i.i.d. assumption and opaque decision-making. This paper examines interpretability in deep neural…

Computer Vision and Pattern Recognition · Computer Science 2025-04-09 Mohammad Hossein Najafi , Mohammad Morsali , Mohammadreza Pashanejad , Saman Soleimani Roudi , Mohammad Norouzi , Saeed Bagheri Shouraki

Advances in deep learning (DL) have resulted in impressive accuracy in some medical image classification tasks, but often deep models lack interpretability. The ability of these models to explain their decisions is important for fostering…

Deep Neural Networks (DNNs) do not inherently compute or exhibit empirically-justified task confidence. In mission critical applications, it is important to both understand associated DNN reasoning and its supporting evidence. In this…

Machine Learning · Computer Science 2024-03-14 Paul Ardis , Arjuna Flenner

Artificial Intelligence is rapidly advancing and radically impacting everyday life, driven by the increasing availability of computing power. Despite this trend, the adoption of AI in real-world healthcare is still limited. One of the main…

Artificial Intelligence · Computer Science 2024-12-02 Akshat Dubey , Zewen Yang , Georges Hattab

The rapid evolution of machine learning (ML) has led to the widespread adoption of complex "black box" models, such as deep neural networks and ensemble methods. These models exhibit exceptional predictive performance, making them…

Machine Learning · Computer Science 2025-03-28 Moncef Garouani , Josiane Mothe , Ayah Barhrhouj , Julien Aligon

Estimating treatment effects from observational data is of central interest across numerous application domains. Individual treatment effect offers the most granular measure of treatment effect on an individual level, and is the most useful…

Machine Learning · Statistics 2024-08-06 Hengrui Cai , Huaqing Jin , Lexin Li

One of the largest drivers of social inequality is unequal access to personal tutoring, with wealthier individuals able to afford it, while the majority cannot. Affordable, effective AI tutors offer a scalable solution. We focus on adaptive…

Artificial Intelligence · Computer Science 2025-10-01 Tom Quilter , Anastasia Ilick , Karen Poon , Richard Turner

Social platforms such as Reddit have a network of communities of shared interests, with a prevalence of posts and comments from which one can infer users' Personal Information Identifiers (PIIs). While such self-disclosures can lead to…

Computation and Language · Computer Science 2025-08-01 Shalini Jangra , Suparna De , Nishanth Sastry , Saeed Fadaei

Accurate fault detection in high-dimensional industrial environments remains a major challenge due to the inherent complexity, noise, and redundancy in sensor data. This paper introduces CLAIRE, i.e., a hybrid end-to-end learning framework…

Machine Learning · Computer Science 2026-03-09 Mohammadhossein Ghahramani , Mengchu Zhou

Recent efforts in Machine Learning (ML) interpretability have focused on creating methods for explaining black-box ML models. However, these methods rely on the assumption that simple approximations, such as linear models or decision-trees,…

Machine Learning · Computer Science 2019-06-13 Owen Lahav , Nicholas Mastronarde , Mihaela van der Schaar

Whilst an abundance of techniques have recently been proposed to generate counterfactual explanations for the predictions of opaque black-box systems, markedly less attention has been paid to exploring the uncertainty of these generated…

Machine Learning · Computer Science 2021-07-22 Eoin Delaney , Derek Greene , Mark T. Keane

There is a rich and growing literature on producing local contrastive/counterfactual explanations for black-box models (e.g. neural networks). In these methods, for an input, an explanation is in the form of a contrast point differing in…

Machine Learning · Computer Science 2020-10-30 Tejaswini Pedapati , Avinash Balakrishnan , Karthikeyan Shanmugam , Amit Dhurandhar

While recent advancements in Neural Ranking Models have resulted in significant improvements over traditional statistical retrieval models, it is generally acknowledged that the use of large neural architectures and the application of…

Information Retrieval · Computer Science 2025-05-13 Sourav Saha , Harsh Agarwal , V Venktesh , Avishek Anand , Swastik Mohanty , Debapriyo Majumdar , Mandar Mitra

Clinicians are often very sceptical about applying automatic image processing approaches, especially deep learning based methods, in practice. One main reason for this is the black-box nature of these approaches and the inherent problem of…

InterpretML is an open-source Python package which exposes machine learning interpretability algorithms to practitioners and researchers. InterpretML exposes two types of interpretability - glassbox models, which are machine learning models…

Machine Learning · Computer Science 2019-09-23 Harsha Nori , Samuel Jenkins , Paul Koch , Rich Caruana

How to interpret a data mining model has received much attention recently, because people may distrust a black-box predictive model if they do not understand how the model works. Hence, it will be trustworthy if a model can provide…

Machine Learning · Computer Science 2025-03-20 Zengyou He , Pengju Li , Yifan Tang , Lianyu Hu , Mudi Jiang , Yan Liu
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