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A novel computing model, called \emph{Probe Machine}, is proposed in this paper. Different from Turing Machine, Probe Machine is a fully-parallel computing model in the sense that it can simultaneously process multiple pairs of data, rather…

Computational Complexity · Computer Science 2016-03-01 Jin Xu

DNA Self-Assembly has emerged as an interdisciplinary field with many intriguing applications such DNA bio-sensor, DNA circuits, DNA storage, drug delivery etc. Tile assembly model of DNA has been studied for various computational…

Emerging Technologies · Computer Science 2015-02-20 Shalin Shah , Parth Dave , Manish K Gupta

The development of autonomous molecular computers capable of making independent decisions in vivo regarding local drug administration may revolutionize medical science. Recently Benenson at el (2004) have envisioned one form such a ``smart…

Computational Complexity · Computer Science 2019-10-01 David Soloveichik , Erik Winfree

DNA data storage offers a high-density, long-term alternative to traditional storage systems, addressing the exponential growth of digital data. Composite DNA extends this paradigm by leveraging mixtures of nucleotides to increase storage…

Information Theory · Computer Science 2026-02-13 Busra Tegin , Tolga M Duman

DNA self-assembly is a robust and programmable approach for building structures at nanoscale. Researchers around the world have proposed and implemented different techniques to build two dimensional and three dimensional nano structures.…

Emerging Technologies · Computer Science 2014-05-19 Shikhar Kumar Gupta , Foram Joshi , Dixita Limbachiya , Manish K Gupta

High-performance computing (HPC) is reshaping computational drug discovery by enabling large-scale, time-efficient molecular simulations. In this work, we explore HPC-driven pipelines for Alzheimer's disease drug discovery, focusing on…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-03 Paul Ruiz Alliata , Diana Rubaga , Daniel Kumlin , Alberto Puliga

Drug discovery has become a main challenge in our society, following the Covid-19 pandemic. Even pharmaceutical companies are already using computing to accelerate drug discovery. They are increasingly interested in Quantum Computing with a…

Quantum Physics · Physics 2024-02-16 Anthony Chagneau , Yousra Massaoudi , Imene Derbali , Linda Yahiaoui

The yearly global production of data is growing exponentially, outpacing the capacity of existing storage media, such as tape and disk, and surpassing our ability to store it. DNA storage - the representation of arbitrary information as…

Quantitative Methods · Quantitative Biology 2023-10-04 Thomas Heinis , Roman Sokolovskii , Jamie J. Alnasir

Memcomputing is a novel computing paradigm beyond the von-Neumann one. Its digital version is designed for the efficient solution of combinatorial optimization problems, which emerge in various fields of science and technology. Previously,…

Emerging Technologies · Computer Science 2024-02-02 Dyk Chung Nguyen , Yuan-Hang Zhang , Massimiliano Di Ventra , Yuriy V. Pershin

While deep learning excels in natural image and language processing, its application to high-dimensional data faces computational challenges due to the dimensionality curse. Current large-scale data tools focus on business-oriented…

Machine Learning · Computer Science 2025-07-01 Chen Zhang

As deep neural networks require tremendous amount of computation and memory, analog computing with emerging memory devices is a promising alternative to digital computing for edge devices. However, because of the increasing simulation time…

Machine Learning · Computer Science 2021-01-21 Chaeun Lee , Seyoung Kim

Extensively exploring protein conformational landscapes remains a major challenge in computational biology due to the high computational cost involved in dynamic physics-based simulations. In this work, we propose a novel pipeline, MoDyGAN,…

Machine Learning · Computer Science 2025-07-21 Jingbo Liang , Bruna Jacobson

Computation biology helps to understand all processes in organisms from interaction of molecules to complex functions of whole organs. Therefore, there is a need for mathematical methods and models that deliver logical explanations in a…

Molecular Networks · Quantitative Biology 2018-10-10 Ines Abdeljaoued-Tej , Alia BenKahla , Ghassen Haddad , Annick Valibouze

In this paper we propose a biomolecular implementation of the push-down automaton (one of theoretical models of computing device with unbounded memory) using DNA molecules. The idea of this improved implementation was inspired by Cavaliere…

Formal Languages and Automata Theory · Computer Science 2011-11-28 Tadeusz Krasinski , Sebastian Sakowski , Tomasz Poplawski

Researchers in the field of DNA-based chaotic cryptography have recently proposed a set of novel and efficient image encryption algorithms. In this paper, we present a comprehensive summary of those techniques, which are available in the…

Cryptography and Security · Computer Science 2015-05-08 Chiranjoy Chattopadhyay , Bikramjit Sarkar , Debaprasad Mukherjee

Karppa & Kaski (2019) proposed a novel ``broken" or ``opportunistic" matrix multiplication algorithm, based on a variant of Strassen's algorithm, and used this to develop new algorithms for Boolean matrix multiplication, among other tasks.…

Data Structures and Algorithms · Computer Science 2024-09-05 David G. Harris

Deep learning has become a powerful tool in computational biology, revolutionising the analysis and interpretation of biological data over time. In our article review, we delve into various aspects of deep learning in computational biology.…

We present an efficient quantum algorithm to simulate nonlinear differential equations with polynomial vector fields of arbitrary degree on quantum platforms. Models of physical systems that are governed by ordinary differential equations…

Dynamical Systems · Mathematics 2023-02-08 Amit Surana , Abeynaya Gnanasekaran , Tuhin Sahai

In recent years, with the rapid development of electro-optic modulators, optical computing has become a potential excellent candidate for various computing tasks. New structures and devices for optical computing are emerging one after…

Optics · Physics 2023-09-20 Yufeng Zhang , Hao Yan , Kaizhi Wang

As computer scientists working in bioinformatics/computational biology, we often face the challenge of coming up with an algorithm to answer a biological question. This occurs in many areas, such as variant calling, alignment, and assembly.…

Data Structures and Algorithms · Computer Science 2018-01-04 Paul Medvedev
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