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Major depressive disorder (MDD) is a prevalent mental disorder associated with complex neurobiological changes that cannot be fully captured using a single imaging modality. The use of multimodal magnetic resonance imaging (MRI) provides a…
Deep learning-based models in medical imaging often struggle to generalize effectively to new scans due to data heterogeneity arising from differences in hardware, acquisition parameters, population, and artifacts. This limitation presents…
Resting-state functional MRI (rs-fMRI) is increasingly employed in multi-site research to aid neurological disorder analysis. Existing studies usually suffer from significant cross-site/domain data heterogeneity caused by site effects such…
Single subject prediction of brain disorders from neuroimaging data has gained increasing attention in recent years. Yet, for some heterogeneous disorders such as major depression disorder (MDD) and autism spectrum disorder (ASD), the…
Brain disorders are a major challenge to global health, causing millions of deaths each year. Accurate diagnosis of these diseases relies heavily on advanced medical imaging techniques such as Magnetic Resonance Imaging (MRI) and Computed…
Alzheimer's disease (AD) is an irreversible neurodegenerative disorder, and early diagnosis is critical for timely intervention. However, most existing classification frameworks face challenges in multicenter studies, as they often neglect…
Learning deep neural networks that are generalizable across different domains remains a challenge due to the problem of domain shift. Unsupervised domain adaptation is a promising avenue which transfers knowledge from a source domain to a…
Unsupervised domain adaptive (UDA) person re-identification (ReID) aims to transfer the knowledge from the labeled source domain to the unlabeled target domain for person matching. One challenge is how to generate target domain samples with…
Accurate identification of late-life depression (LLD) using structural brain MRI is essential for monitoring disease progression and facilitating timely intervention. However, existing learning-based approaches for LLD detection are often…
The primary goal of this work is to study the effectiveness of an unsupervised domain adaptation approach for various applications such as binary classification and anomaly detection in the context of Alzheimer's disease (AD) detection for…
Depression poses serious public health risks, including suicide, underscoring the urgency of timely and scalable screening. Multimodal automatic depression detection (ADD) offers a promising solution; however, widely studied audio- and…
The application of deep learning to build accurate predictive models from functional neuroimaging data is often hindered by limited dataset sizes. Though data augmentation can help mitigate such training obstacles, most data augmentation…
Increasing the volume of training data can enable the auxiliary diagnostic algorithms for Autism Spectrum Disorder (ASD) to learn more accurate and stable models. However, due to the significant heterogeneity and domain shift in rs-fMRI…
Adapting a deep learning model to a specific target individual is a challenging facial expression recognition (FER) task that may be achieved using unsupervised domain adaptation (UDA) methods. Although several UDA methods have been…
Unsupervised domain adaptation (UDA) involves a supervised loss in a labeled source domain and an unsupervised loss in an unlabeled target domain, which often faces more severe overfitting (than classical supervised learning) as the…
Medical Foundation Models (MFMs), trained on large-scale datasets, have demonstrated superior performance across various tasks. However, these models still struggle with domain gaps in practical applications. Specifically, even after…
Most existing person re-identification (Re-ID) approaches follow a supervised learning framework, in which a large number of labelled matching pairs are required for training. Such a setting severely limits their scalability in real-world…
Automatic semantic segmentation of magnetic resonance imaging (MRI) images using deep neural networks greatly assists in evaluating and planning treatments for various clinical applications. However, training these models is conditioned on…
Major depressive disorder (MDD) is one of the most common mental disorders, with significant impacts on many daily activities and quality of life. It stands as one of the most common mental disorders globally and ranks as the second leading…
The scarcity of annotated data, particularly for rare diseases, limits the variability of training data and the range of detectable lesions, presenting a significant challenge for supervised anomaly detection in medical imaging. To solve…