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We demonstrate a new computational illumination technique that achieves large space-bandwidth-time product, for quantitative phase imaging of unstained live samples in vitro. Microscope lenses can have either large field of view (FOV) or…

Optics · Physics 2015-10-16 Lei Tian , Ziji Liu , Li-Hao Yeh , Michael Chen , Jingshan Zhong , Laura Waller

Scanning Probe Microscopy (SPM) is the primary tool for exploring nanoscale functionality, yet standard single-frequency operation is fundamentally limited, because the dynamic tip-sample interaction is mathematically underdetermined. While…

Light microscopy is a widespread and inexpensive imaging technique facilitating biomedical discovery and diagnostics. However, light diffraction barrier and imperfections in optics limit the level of detail of the acquired images. The…

Quantitative Methods · Quantitative Biology 2026-03-24 Rui Li , Gabriel della Maggiora , Vardan Andriasyan , Anthony Petkidis , Artsemi Yushkevich , Mikhail Kudryashev , Artur Yakimovich

A giant atom is an artificial matter configuration whose spatial scale is comparable to the wavelength of the interacting electromagnetic wave, such that the usual electric-dipole approximation is no longer valid. As a consequence, certain…

Quantum Physics · Physics 2026-05-13 S. R. He , S. N. Wang , Y. L. Zhang , P. H. Ouyang , L. F. Wei

The Slicer Combined with Array of Lenslets for Exoplanet Spectroscopy (SCALES) instrument is a lenslet-based integral field spectrograph that will operate at 2 to 5 microns, imaging and characterizing colder (and thus older) planets than…

Spiking Neural Networks (SNNs) are efficient computation models to perform spatio-temporal pattern recognition on {resource}- and {power}-constrained platforms. SNNs executed on neuromorphic hardware can further reduce energy consumption of…

Neural and Evolutionary Computing · Computer Science 2020-12-01 Adarsha Balaji , Anup Das

In traditional optical imaging systems, the spatial resolution is limited by the physics of diffraction, which acts as a low-pass filter. The information on sub-wavelength features is carried by evanescent waves, never reaching the camera,…

Optics · Physics 2018-12-13 Oren Solomon , Yonina C. Eldar , Maor Mutzafi , Mordechai Segev

A deep learning based non-line-of-sight (NLOS) imaging system is developed to image an occluded object off a scattering surface. The neural net is trained using only handwritten digits, and yet exhibits capability to reconstruct patterns…

Image and Video Processing · Electrical Eng. & Systems 2020-05-05 Chen Zhou , Cheng-Yu Wang , Zhiwen Liu

Computational spectrometers are pivotal in enabling low-cost, in-situ and rapid spectral analysis, with potential applications in chemistry, biology, and environmental science. However, filter-based spectral encoding approaches typically…

ESCAPE is a free python package and framework for creating applications for simulating and fitting of X-ray and neutron scattering data with current support for specular reflectivity, polarized neutron reflectometry, high resolution X-ray…

Computational Engineering, Finance, and Science · Computer Science 2020-11-11 Denis Korolkov , Stepan Rakhimov

This paper describes the architecture and demonstrates the capabilities of a newly developed, physically-based imaging simulator environment called SISPO, developed for small solar system body fly-by and terrestrial planet surface mission…

Fluorescent molecules are versatile nanoscale emitters that enable detailed observations of biophysical processes with nanoscale resolution. Because they are well-approximated as electric dipoles, imaging systems can be designed to…

Optics · Physics 2024-03-26 Tingting Wu , Matthew D. Lew

In a previous paper we proposed a modification of metal-coated tapered-fibre aperture probes for scanning near-field optical microscopes. The modification consists of radial corrugations of the metal-dielectric interface oriented inward the…

Optics · Physics 2008-01-03 Tomasz J. Antosiewicz , Tomasz Szoplik

Focusing light through dynamically varying heterogeneous media is a sought-after goal with important applications ranging from free-space communication to nano-surgery. The underlying challenge is to control the optical wavefront with a…

Optical fibres are essential for many types of highly-multiplexed and precision spectroscopy. The success of the new generation of multifibre instruments under construction to investigate fundamental problems in cosmology, such as the…

Instrumentation and Methods for Astrophysics · Physics 2015-06-05 Jeremy Allington-Smith , Graham Murray , Ulrike Lemke

Fourier Ptychographic Microscopy (FPM) is a recent technique to overcome the diffraction limit of a low numerical aperture (NA) objective lens by algorithmic post-processing of several lower resolved images. It can increase the…

The semi-empirical pseudopotential method (SEPM) has been widely applied to provide computational insights into the electronic structure, photophysics, and charge carrier dynamics of nanoscale materials. We present "DeepPseudopot", a…

Materials Science · Physics 2026-01-01 Kailai Lin , Matthew J. Coley-O'Rourke , Eran Rabani

Magnetron sputtering is an essential technique in combinatorial materials science, enabling the efficient synthesis of thin-film materials libraries with continuous compositional gradients. For exploring multidimensional search spaces,…

Materials Science · Physics 2024-11-22 Felix Thelen , Rico Zehl , Jan Lukas Bürgel , Diederik Depla , Alfred Ludwig

Hyperspectral imaging is useful for applications ranging from medical diagnostics to agricultural crop monitoring; however, traditional scanning hyperspectral imagers are prohibitively slow and expensive for widespread adoption. Snapshot…

Image and Video Processing · Electrical Eng. & Systems 2020-09-30 Kristina Monakhova , Kyrollos Yanny , Neerja Aggarwal , Laura Waller

In this paper we present a method to robustly evaluate the quantitative accuracy of various tomographic phase microscopy (TPM) methods with a multiple scattering 3D-printed microphantom with known geometry and refractive index distribution.…

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