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In many modern applications, discretely-observed data may be naturally understood as a set of functions. Functional data often exhibit two confounded sources of variability: amplitude (y-axis) and phase (x-axis). The extraction of amplitude…

Methodology · Statistics 2025-05-22 Yoonji Kim , Oksana A. Chkrebtii , Sebastian A. Kurtek

Low-dimensional embeddings of knowledge graphs and behavior graphs have proved remarkably powerful in varieties of tasks, from predicting unobserved edges between entities to content recommendation. The two types of graphs can contain…

Machine Learning · Computer Science 2019-08-29 Yuting Ye , Xuwu Wang , Jiangchao Yao , Kunyang Jia , Jingren Zhou , Yanghua Xiao , Hongxia Yang

Image data are increasingly encountered and are of growing importance in many areas of science. Much of these data are quantitative image data, which are characterized by intensities that represent some measurement of interest in the…

Untargeted metabolomics based on liquid chromatography-mass spectrometry technology is quickly gaining widespread application given its ability to depict the global metabolic pattern in biological samples. However, the data is noisy and…

Methodology · Statistics 2026-03-24 Guoxuan Ma , Jian Kang , Tianwei Yu

Functional principal components analysis is a popular tool for inference on functional data. Standard approaches rely on an eigendecomposition of a smoothed covariance surface in order to extract the orthonormal functions representing the…

Methodology · Statistics 2021-04-02 Tui H. Nolan , Jeff Goldsmith , David Ruppert

We introduce a novel Bayesian approach for both covariate selection and sparse precision matrix estimation in the context of high-dimensional Gaussian graphical models involving multiple responses. Our approach provides a sparse estimation…

Methodology · Statistics 2024-09-25 Anwesha Chakravarti , Naveen N. Narishetty , Feng Liang

Task functional magnetic resonance imaging (fMRI) is a type of neuroimaging data used to identify areas of the brain that activate during specific tasks or stimuli. These data are conventionally modeled using a massive univariate approach…

Methodology · Statistics 2022-11-04 Daniel A. Spencer , David Bolin , Amanda F. Mejia

We consider functional data where an underlying smooth curve is composed not just with errors, but also with irregular spikes. We propose an approach that, combining regularized spline smoothing and an Expectation-Maximization algorithm,…

Methodology · Statistics 2023-07-18 Huy Dang , Marzia Cremona , Francesca Chiaromonte

A novel approach to perform unsupervised sequential learning for functional data is proposed. Our goal is to extract reference shapes (referred to as templates) from noisy, deformed and censored realizations of curves and images. Our model…

Methodology · Statistics 2016-04-05 Florian Maire , Eric Moulines , Sidonie Lefebvre

In many areas of science one aims to estimate latent sub-population mean curves based only on observations of aggregated population curves. By aggregated curves we mean linear combination of functional data that cannot be observed…

Methodology · Statistics 2011-02-15 Ronaldo Dias , Nancy L. Garcia , Alexandra M. Schmidt

Handling latent variables in Structural Equation Models (SEMs) in a case where both the latent variables and their corresponding indicators in the measurement error part of the model are random curves presents significant challenges,…

Methodology · Statistics 2024-12-30 Fatemeh Asgari , Valeria Vitelli , Uta Sailer

Linear mixed effects models are widely used in statistical modelling. We consider a mixed effects model with Bayesian variable selection in the random effects using spike-and-slab priors and developed a variational Bayes inference scheme…

Methodology · Statistics 2024-08-15 M-Z. Spyropoulou , J. Hopker , J. E. Griffin

Functional data registration is a necessary processing step for many applications. The observed data can be inherently noisy, often due to measurement error or natural process uncertainty, which most functional alignment methods cannot…

Methodology · Statistics 2021-06-09 J. Derek Tucker , Lyndsay Shand , Kenny Chowdhary

In environmental studies, realistic simulations are essential for understanding complex systems. Statistical emulation with Gaussian processes (GPs) in functional data models have become a standard tool for this purpose. Traditional…

Applications · Statistics 2024-09-26 R. Jacob Andros , Rajarshi Guhaniyogi , Devin Francom , Donatella Pasqualini

Spatial whole-brain Bayesian modeling of task-related functional magnetic resonance imaging (fMRI) is a great computational challenge. Most of the currently proposed methods therefore do inference in subregions of the brain separately or do…

Computation · Statistics 2017-01-03 Per Sidén , Anders Eklund , David Bolin , Mattias Villani

We develop a Bayesian variable selection method, called SVEN, based on a hierarchical Gaussian linear model with priors placed on the regression coefficients as well as on the model space. Sparsity is achieved by using degenerate spike…

Methodology · Statistics 2020-08-04 Dongjin Li , Somak Dutta , Vivekananda Roy

We develop a new method for simultaneously selecting fixed and random effects in a multilevel functional regression model. The proposed method is motivated by accelerometer-derived physical activity data from the 2011-12 cohort of the…

Methodology · Statistics 2025-10-24 Rahul Ghosal , Marcos Matabuena , Enakshi Saha

Collective variable-based enhanced sampling methods are routinely used on systems with metastable states, where high free energy barriers impede proper sampling of the free energy landscapes when using conventional molecular dynamics…

Chemical Physics · Physics 2022-08-09 Benjamin Pampel , Omar Valsson

In modern contexts, some types of data are observed in high-resolution, essentially continuously in time. Such data units are best described as taking values in a space of functions. Subject units carrying the observations may have…

Methodology · Statistics 2021-07-21 Arkaprava Roy , Shubhashis Ghosal

We propose a Bayesian procedure for simultaneous variable and covariance selection using continuous spike-and-slab priors in multivariate linear regression models where q possibly correlated responses are regressed onto p predictors. Rather…

Methodology · Statistics 2019-03-29 Sameer K. Deshpande , Veronika Rockova , Edward I. George