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Federated learning (FL) is increasingly adopted in domains like healthcare, where data privacy is paramount. A fundamental challenge in these systems is statistical heterogeneity-the fact that data distributions vary significantly across…

Machine Learning · Computer Science 2026-02-12 Zijian Wang , Xiaofei Zhang , Xin Zhang , Yukun Liu , Qiong Zhang

Recent advances in communication technologies and Internet-of-Medical-Things have transformed smart healthcare enabled by artificial intelligence (AI). Traditionally, AI techniques require centralized data collection and processing that may…

Federated learning has received significant attention for its ability to simultaneously protect customer privacy and leverage distributed data from multiple devices for model training. However, conventional approaches often focus on…

Machine Learning · Computer Science 2025-10-07 Jiahao Zeng , Wolong Xing , Liangtao Shi , Xin Huang , Jialin Wang , Zhile Cao , Zhenkui Shi

Federated Learning (FL) enables multiple clients to collaboratively learn a machine learning model without exchanging their own local data. In this way, the server can exploit the computational power of all clients and train the model on a…

Machine Learning · Computer Science 2023-07-04 Song Wang , Xingbo Fu , Kaize Ding , Chen Chen , Huiyuan Chen , Jundong Li

Deep learning models can enable accurate and efficient disease diagnosis, but have thus far been hampered by the data scarcity present in the medical world. Automated diagnosis studies have been constrained by underpowered single-center…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Akis Linardos , Kaisar Kushibar , Sean Walsh , Polyxeni Gkontra , Karim Lekadir

Research increasingly relies on computational methods to analyze experimental data and predict molecular properties. Current approaches often require researchers to use a variety of tools for statistical analysis and machine learning,…

Quantitative Methods · Quantitative Biology 2025-12-01 Luke Rimmo Lego , Samantha Gauthier , Denver Jn. Baptiste

Machine learning relies on the availability of a vast amount of data for training. However, in reality, most data are scattered across different organizations and cannot be easily integrated under many legal and practical constraints. In…

Machine Learning · Computer Science 2020-06-25 Yang Liu , Yan Kang , Chaoping Xing , Tianjian Chen , Qiang Yang

Data privacy is a major concern in industries such as healthcare or finance. The requirement to safeguard privacy is essential to prevent data breaches and misuse, which can have severe consequences for individuals and organisations.…

Machine Learning · Computer Science 2024-12-18 Jose L Salmeron , Irina Arévalo

Causal inference in modern largescale systems faces growing challenges, including highdimensional covariates, multi-valued treatments, massive observational (OBS) data, and limited randomized controlled trial (RCT) samples due to cost…

Methodology · Statistics 2026-02-27 Yuxi Du , Zhiheng Zhang , Haoxuan Li , Cong Fang , Jixing Xu , Peng Zhen , Jiecheng Guo

The limited representation of minorities and disadvantaged populations in large-scale clinical and genomics research has become a barrier to translating precision medicine research into practice. Due to heterogeneity across populations,…

Machine Learning · Statistics 2021-08-30 Sai Li , Tianxi Cai , Rui Duan

Partial model personalization, which encompasses both shared and personal variables in its formulation, is a critical optimization problem in federated learning. It balances individual client needs with collective knowledge utilization, and…

Optimization and Control · Mathematics 2023-10-02 Yiming Chen , Liyuan Cao , Kun Yuan , Zaiwen Wen

Online collaborative medical prediction platforms offer convenience and real-time feedback by leveraging massive electronic health records. However, growing concerns about privacy and low prediction quality can deter patient participation…

Machine Learning · Computer Science 2025-07-16 Shao-Bo Lin , Xiaotong Liu , Yao Wang

Decentralized federated learning enables learning of data representations from multiple sources without compromising the privacy of the clients. In applications like medical image segmentation, where obtaining a large annotated dataset from…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Siladittya Manna , Suresh Das , Sayantari Ghosh , Saumik Bhattacharya

Although machine learning (ML) has shown promise in numerous domains, there are concerns about generalizability to out-of-sample data. This is currently addressed by centrally sharing ample, and importantly diverse, data from multiple…

Machine Learning · Computer Science 2022-12-07 Sarthak Pati , Ujjwal Baid , Brandon Edwards , Micah Sheller , Shih-Han Wang , G Anthony Reina , Patrick Foley , Alexey Gruzdev , Deepthi Karkada , Christos Davatzikos , Chiharu Sako , Satyam Ghodasara , Michel Bilello , Suyash Mohan , Philipp Vollmuth , Gianluca Brugnara , Chandrakanth J Preetha , Felix Sahm , Klaus Maier-Hein , Maximilian Zenk , Martin Bendszus , Wolfgang Wick , Evan Calabrese , Jeffrey Rudie , Javier Villanueva-Meyer , Soonmee Cha , Madhura Ingalhalikar , Manali Jadhav , Umang Pandey , Jitender Saini , John Garrett , Matthew Larson , Robert Jeraj , Stuart Currie , Russell Frood , Kavi Fatania , Raymond Y Huang , Ken Chang , Carmen Balana , Jaume Capellades , Josep Puig , Johannes Trenkler , Josef Pichler , Georg Necker , Andreas Haunschmidt , Stephan Meckel , Gaurav Shukla , Spencer Liem , Gregory S Alexander , Joseph Lombardo , Joshua D Palmer , Adam E Flanders , Adam P Dicker , Haris I Sair , Craig K Jones , Archana Venkataraman , Meirui Jiang , Tiffany Y So , Cheng Chen , Pheng Ann Heng , Qi Dou , Michal Kozubek , Filip Lux , Jan Michálek , Petr Matula , Miloš Keřkovský , Tereza Kopřivová , Marek Dostál , Václav Vybíhal , Michael A Vogelbaum , J Ross Mitchell , Joaquim Farinhas , Joseph A Maldjian , Chandan Ganesh Bangalore Yogananda , Marco C Pinho , Divya Reddy , James Holcomb , Benjamin C Wagner , Benjamin M Ellingson , Timothy F Cloughesy , Catalina Raymond , Talia Oughourlian , Akifumi Hagiwara , Chencai Wang , Minh-Son To , Sargam Bhardwaj , Chee Chong , Marc Agzarian , Alexandre Xavier Falcão , Samuel B Martins , Bernardo C A Teixeira , Flávia Sprenger , David Menotti , Diego R Lucio , Pamela LaMontagne , Daniel Marcus , Benedikt Wiestler , Florian Kofler , Ivan Ezhov , Marie Metz , Rajan Jain , Matthew Lee , Yvonne W Lui , Richard McKinley , Johannes Slotboom , Piotr Radojewski , Raphael Meier , Roland Wiest , Derrick Murcia , Eric Fu , Rourke Haas , John Thompson , David Ryan Ormond , Chaitra Badve , Andrew E Sloan , Vachan Vadmal , Kristin Waite , Rivka R Colen , Linmin Pei , Murat Ak , Ashok Srinivasan , J Rajiv Bapuraj , Arvind Rao , Nicholas Wang , Ota Yoshiaki , Toshio Moritani , Sevcan Turk , Joonsang Lee , Snehal Prabhudesai , Fanny Morón , Jacob Mandel , Konstantinos Kamnitsas , Ben Glocker , Luke V M Dixon , Matthew Williams , Peter Zampakis , Vasileios Panagiotopoulos , Panagiotis Tsiganos , Sotiris Alexiou , Ilias Haliassos , Evangelia I Zacharaki , Konstantinos Moustakas , Christina Kalogeropoulou , Dimitrios M Kardamakis , Yoon Seong Choi , Seung-Koo Lee , Jong Hee Chang , Sung Soo Ahn , Bing Luo , Laila Poisson , Ning Wen , Pallavi Tiwari , Ruchika Verma , Rohan Bareja , Ipsa Yadav , Jonathan Chen , Neeraj Kumar , Marion Smits , Sebastian R van der Voort , Ahmed Alafandi , Fatih Incekara , Maarten MJ Wijnenga , Georgios Kapsas , Renske Gahrmann , Joost W Schouten , Hendrikus J Dubbink , Arnaud JPE Vincent , Martin J van den Bent , Pim J French , Stefan Klein , Yading Yuan , Sonam Sharma , Tzu-Chi Tseng , Saba Adabi , Simone P Niclou , Olivier Keunen , Ann-Christin Hau , Martin Vallières , David Fortin , Martin Lepage , Bennett Landman , Karthik Ramadass , Kaiwen Xu , Silky Chotai , Lola B Chambless , Akshitkumar Mistry , Reid C Thompson , Yuriy Gusev , Krithika Bhuvaneshwar , Anousheh Sayah , Camelia Bencheqroun , Anas Belouali , Subha Madhavan , Thomas C Booth , Alysha Chelliah , Marc Modat , Haris Shuaib , Carmen Dragos , Aly Abayazeed , Kenneth Kolodziej , Michael Hill , Ahmed Abbassy , Shady Gamal , Mahmoud Mekhaimar , Mohamed Qayati , Mauricio Reyes , Ji Eun Park , Jihye Yun , Ho Sung Kim , Abhishek Mahajan , Mark Muzi , Sean Benson , Regina G H Beets-Tan , Jonas Teuwen , Alejandro Herrera-Trujillo , Maria Trujillo , William Escobar , Ana Abello , Jose Bernal , Jhon Gómez , Joseph Choi , Stephen Baek , Yusung Kim , Heba Ismael , Bryan Allen , John M Buatti , Aikaterini Kotrotsou , Hongwei Li , Tobias Weiss , Michael Weller , Andrea Bink , Bertrand Pouymayou , Hassan F Shaykh , Joel Saltz , Prateek Prasanna , Sampurna Shrestha , Kartik M Mani , David Payne , Tahsin Kurc , Enrique Pelaez , Heydy Franco-Maldonado , Francis Loayza , Sebastian Quevedo , Pamela Guevara , Esteban Torche , Cristobal Mendoza , Franco Vera , Elvis Ríos , Eduardo López , Sergio A Velastin , Godwin Ogbole , Dotun Oyekunle , Olubunmi Odafe-Oyibotha , Babatunde Osobu , Mustapha Shu'aibu , Adeleye Dorcas , Mayowa Soneye , Farouk Dako , Amber L Simpson , Mohammad Hamghalam , Jacob J Peoples , Ricky Hu , Anh Tran , Danielle Cutler , Fabio Y Moraes , Michael A Boss , James Gimpel , Deepak Kattil Veettil , Kendall Schmidt , Brian Bialecki , Sailaja Marella , Cynthia Price , Lisa Cimino , Charles Apgar , Prashant Shah , Bjoern Menze , Jill S Barnholtz-Sloan , Jason Martin , Spyridon Bakas

The provision of social care applications is crucial for elderly people to improve their quality of life and enables operators to provide early interventions. Accurate predictions of user dropouts in healthy ageing applications are…

Machine Learning · Computer Science 2023-09-11 Christos Chrysanthos Nikolaidis , Vasileios Perifanis , Nikolaos Pavlidis , Pavlos S. Efraimidis

The performance of coverage-based fault localization greatly depends on the quality of test cases being executed. These test cases execute some lines of the given program and determine whether the underlying tests are passed or failed. In…

Software Engineering · Computer Science 2020-06-17 Shuvalaxmi Dass , Xiaozhen Xue , Akbar Siami Namin

In the age of cloud computing, data privacy protection has become a major challenge, especially when sharing sensitive data across cloud environments. However, how to optimize collaboration across cloud environments remains an unresolved…

Cryptography and Security · Computer Science 2025-05-20 Huaiying Luo , Cheng Ji

Multiple medical institutions collaboratively training a model using federated learning (FL) has become a promising solution for maximizing the potential of data-driven models, yet the non-independent and identically distributed (non-iid)…

Image and Video Processing · Electrical Eng. & Systems 2022-04-26 Meirui Jiang , Zirui Wang , Qi Dou

Data-driven evolutionary optimization has witnessed great success in solving complex real-world optimization problems. However, existing data-driven optimization algorithms require that all data are centrally stored, which is not always…

Neural and Evolutionary Computing · Computer Science 2021-02-17 Jinjin Xu , Yaochu Jin , Wenli Du , Sai Gu

Federated learning learns from scattered data by fusing collaborative models from local nodes. However, due to chaotic information distribution, the model fusion may suffer from structural misalignment with regard to unmatched parameters.…

Machine Learning · Computer Science 2022-03-22 Fuxun Yu , Weishan Zhang , Zhuwei Qin , Zirui Xu , Di Wang , Chenchen Liu , Zhi Tian , Xiang Chen