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Federated learning has attracted significant attention as a privacy-preserving framework for training personalised models on multi-source heterogeneous data. However, most existing approaches are unable to handle scenarios where subgroup…

Methodology · Statistics 2025-10-14 Changxin Yang , Zhongyi Zhu , Heng Lian

Federated learning enables training a global machine learning model from data distributed across multiple sites, without having to move the data. This is particularly relevant in healthcare applications, where data is rife with personal,…

Cryptography and Security · Computer Science 2020-02-24 Olivia Choudhury , Aris Gkoulalas-Divanis , Theodoros Salonidis , Issa Sylla , Yoonyoung Park , Grace Hsu , Amar Das

In multicenter biomedical research, integrating data from multiple decentralized sites provides more robust and generalizable findings due to its larger sample size and the ability to account for the between-site heterogeneity. However,…

Methodology · Statistics 2025-12-29 Xiaokang Liu , Yuchen Yang , Yifei Sun , Jiang Bian , Yanyuan Ma , Raymond J. Carroll , Yong Chen

Over the last years, topic modeling has emerged as a powerful technique for organizing and summarizing big collections of documents or searching for particular patterns in them. However, privacy concerns may arise when cross-analyzing data…

Machine Learning · Computer Science 2023-06-13 Lorena Calvo-Bartolomé , Jerónimo Arenas-García

The age of big data has fueled expectations for accelerating learning. The availability of large data sets enables researchers to achieve more powerful statistical analyses and enhances the reliability of conclusions, which can be based on…

Methodology · Statistics 2023-08-22 Ori Becher , Mira Marcus-Kalish , David M. Steinberg

Federated machine learning is a versatile and flexible tool to utilize distributed data from different sources, especially when communication technology develops rapidly and an unprecedented amount of data could be collected on mobile…

Machine Learning · Computer Science 2024-03-12 Tianyi Zhang , Shirui Zhang , Ziwei Chen , Dianbo Liu

Federated learning has attracted considerable interest for collaborative machine learning in healthcare to leverage separate institutional datasets while maintaining patient privacy. However, additional challenges such as poor calibration…

Machine Learning · Computer Science 2022-01-19 Charles Lu , Jayasheree Kalpathy-Cramer

Currently, many contexts exist where distributed learning is difficult or otherwise constrained by security and communication limitations. One common domain where this is a consideration is in Healthcare where data is often governed by…

Cryptography and Security · Computer Science 2023-08-16 Navya Annapareddy , Jade Preston , Judy Fox

This paper proposes a data privacy protection framework based on federated learning, which aims to realize effective cross-domain data collaboration under the premise of ensuring data privacy through distributed learning. Federated learning…

Machine Learning · Computer Science 2025-04-02 Yiwei Zhang , Jie Liu , Jiawei Wang , Lu Dai , Fan Guo , Guohui Cai

The data made available for analysis are becoming more and more complex along several directions: high dimensionality, number of examples and the amount of labels per example. This poses a variety of challenges for the existing machine…

Machine Learning · Computer Science 2020-08-11 Matej Petković , Sašo Džeroski , Dragi Kocev

This work demonstrates how mixed effects random forests enable accurate predictions of depression severity using multimodal physiological and digital activity data collected from an 8-week study involving 31 patients with major depressive…

Machine Learning · Computer Science 2023-01-25 Robert A. Lewis , Asma Ghandeharioun , Szymon Fedor , Paola Pedrelli , Rosalind Picard , David Mischoulon

Federated Learning (FL) offers a promising approach for training clinical AI models without centralizing sensitive patient data. However, its real-world adoption is hindered by challenges related to privacy, resource constraints, and…

In medical image segmentation tasks, Domain Generalization (DG) under the Federated Learning (FL) framework is crucial for addressing challenges related to privacy protection and data heterogeneity. However, traditional federated learning…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Yucheng Song , Chenxi Li , Haokang Ding , Zhining Liao , Zhifang Liao

Machine learning in medical research, by nature, needs careful attention on obeying the regulations of data privacy, making it difficult to train a machine learning model over gathered data from different medical centers. Failure of…

Machine Learning · Computer Science 2021-10-19 Jun Luo , Shandong Wu

We propose an asymptotic framework to analyze the performance of (personalized) federated learning algorithms. In this new framework, we formulate federated learning as a multi-criterion objective, where the goal is to minimize each…

Machine Learning · Computer Science 2022-02-21 Gary Cheng , Karan Chadha , John Duchi

Availability of large, diverse, and multi-national datasets is crucial for the development of effective and clinically applicable AI systems in the medical imaging domain. However, forming a global model by bringing these datasets together…

Machine Learning · Computer Science 2022-09-07 Ece Isik-Polat , Gorkem Polat , Altan Kocyigit , Alptekin Temizel

Data privacy has become a major concern in healthcare due to the increasing digitization of medical records and data-driven medical research. Protecting sensitive patient information from breaches and unauthorized access is critical, as…

Artificial intelligence (AI) has demonstrated considerable potential in the realm of medical imaging. However, the development of high-performance AI models typically necessitates training on large-scale, centralized datasets. This approach…

Cryptography and Security · Computer Science 2025-08-29 Mengyu Sun , Ziyuan Yang , Yongqiang Huang , Hui Yu , Yingyu Chen , Shuren Qi , Andrew Beng Jin Teoh , Yi Zhang

Graph federated learning enables the collaborative extraction of high-order information from distributed subgraphs while preserving the privacy of raw data. However, graph data often exhibits overlap among different clients. Previous…

Machine Learning · Computer Science 2025-12-30 Zihao Zhou , Shusen Yang , Fangyuan Zhao , Xuebin Ren

Federated Learning (FL) enables collaborative training across decentralized clients, but most methods assume aligned feature schemas, an assumption that rarely holds in tabular settings where clients observe only partially overlapping…

Machine Learning · Computer Science 2026-05-18 Imane Hocine , Chaimaa Medjadji , Sylvain Kubler , Gregoire Danoy , Yves Le Traon