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Multimodal representation learning is a challenging task in which previous work mostly focus on either uni-modality pre-training or cross-modality fusion. In fact, we regard modeling multimodal representation as building a skyscraper, where…

Computation and Language · Computer Science 2024-08-15 Ronghao Lin , Haifeng Hu

The integration of different imaging modalities, such as structural, diffusion tensor, and functional magnetic resonance imaging, with deep learning models has yielded promising outcomes in discerning phenotypic characteristics and…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Zhiyuan Li , Hailong Li , Anca L. Ralescu , Jonathan R. Dillman , Mekibib Altaye , Kim M. Cecil , Nehal A. Parikh , Lili He

In recent years, large-scale pre-trained multimodal models (LMMs) generally emerge to integrate the vision and language modalities, achieving considerable success in multimodal tasks, such as text-image classification. The growing size of…

Computer Vision and Pattern Recognition · Computer Science 2025-07-11 Xinyao Yu , Hao Sun , Zeyu Ling , Ziwei Niu , Zhenjia Bai , Rui Qin , Yen-Wei Chen , Lanfen Lin

Multimodal learning significantly benefits cancer survival prediction, especially the integration of pathological images and genomic data. Despite advantages of multimodal learning for cancer survival prediction, massive redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Yilan Zhang , Yingxue Xu , Jianqi Chen , Fengying Xie , Hao Chen

In silico drug-target interaction (DTI) prediction is an important and challenging problem in biomedical research with a huge potential benefit to the pharmaceutical industry and patients. Most existing methods for DTI prediction including…

Machine Learning · Computer Science 2019-08-22 Qingyuan Feng , Evgenia Dueva , Artem Cherkasov , Martin Ester

Accurate prediction of antibody-antigen (Ab-Ag) interfaces is critical for vaccine design, immunodiagnostics, and therapeutic antibody development. However, achieving reliable predictions from sequences alone remains a challenge. In this…

Machine Learning · Computer Science 2025-09-30 Zhang-Yu You , Jiahao Ma , Hongzong Li , Ye-Fan Hu , Jian-Dong Huang

Multimodal graphs, where nodes contain heterogeneous features such as images and text, are increasingly common in real-world applications. Effectively learning on such graphs requires both adaptive intra-modal message passing and efficient…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Xiaobin Hong , Mingkai Lin , Xiaoli Wang , Chaoqun Wang , Wenzhong Li

The rise of social media and the exponential growth of multimodal communication necessitates advanced techniques for Multimodal Information Extraction (MIE). However, existing methodologies primarily rely on direct Image-Text interactions,…

Artificial Intelligence · Computer Science 2024-07-26 Wen Luo , Yu Xia , Shen Tianshu , Sujian Li

Link prediction aims to identify potential missing triples in knowledge graphs. To get better results, some recent studies have introduced multimodal information to link prediction. However, these methods utilize multimodal information…

Artificial Intelligence · Computer Science 2023-03-21 Xinhang Li , Xiangyu Zhao , Jiaxing Xu , Yong Zhang , Chunxiao Xing

Learning representations that transfer well to diverse downstream tasks remains a central challenge in representation learning. Existing paradigms -- contrastive learning, self-supervised masking, and denoising auto-encoders -- balance this…

Machine Learning · Computer Science 2025-09-29 Micha Livne

The integration of visual and textual data in Vision-Language Pre-training (VLP) models is crucial for enhancing vision-language understanding. However, the adversarial robustness of these models, especially in the alignment of image-text…

Multimedia · Computer Science 2025-06-03 Youze Wang , Wenbo Hu , Yinpeng Dong , Hanwang Zhang , Hang Su , Richang Hong

The rapidly evolving field of robotics necessitates methods that can facilitate the fusion of multiple modalities. Specifically, when it comes to interacting with tangible objects, effectively combining visual and tactile sensory data is…

Robotics · Computer Science 2024-01-23 Vedant Dave , Fotios Lygerakis , Elmar Rueckert

We introduce eCLIP, an enhanced version of the CLIP model that integrates expert annotations in the form of radiologist eye-gaze heatmaps. It tackles key challenges in contrastive multi-modal medical imaging analysis, notably data scarcity…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yogesh Kumar , Pekka Marttinen

Protein-protein interaction (PPI) prediction plays a pivotal role in deciphering cellular functions and disease mechanisms. To address the limitations of traditional experimental methods and existing computational approaches in cross-modal…

Machine Learning · Computer Science 2025-04-29 Shengrui XU , Tianchi Lu , Zikun Wang , Jixiu Zhai

Human beings have rich ways of emotional expressions, including facial action, voice, and natural languages. Due to the diversity and complexity of different individuals, the emotions expressed by various modalities may be semantically…

Artificial Intelligence · Computer Science 2023-02-06 Chuan Zhang , Daoxin Zhang , Ruixiu Zhang , Jiawei Li , Jianke Zhu

Obtaining large-scale radiology reports can be difficult for medical images due to various reasons, limiting the effectiveness of contrastive pre-training in the medical image domain and underscoring the need for alternative methods. In…

Computer Vision and Pattern Recognition · Computer Science 2023-12-13 Zihao Zhao , Sheng Wang , Qian Wang , Dinggang Shen

Learning effective joint embedding for cross-modal data has always been a focus in the field of multimodal machine learning. We argue that during multimodal fusion, the generated multimodal embedding may be redundant, and the discriminative…

Machine Learning · Computer Science 2022-12-06 Sijie Mai , Ying Zeng , Haifeng Hu

Multimodal imaging and correlative analysis typically require image alignment. Contrastive learning can generate representations of multimodal images, reducing the challenging task of multimodal image registration to a monomodal one.…

Computer Vision and Pattern Recognition · Computer Science 2023-03-02 Elisabeth Wetzer , Joakim Lindblad , Nataša Sladoje

Recently, Antimicrobial peptides (AMPs) have been an area of interest in the researches, as the first line of defense against the bacteria. They are raising attention as an efficient way of fighting multidrug resistance. Discovering and…

Quantitative Methods · Quantitative Biology 2020-05-06 Neda Zarayeneh , Zahra Hanifeloo

First-principles investigations of electron-phonon interactions (EPIs) play a crucial role in understanding a wide range of phenomena in physics and materials science. Among various approaches, the finite difference method offers a direct…

Materials Science · Physics 2026-02-27 Zun Wang , Wenhui Duan , Zuzhang Lin