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Recently deep learning methods, in particular, convolutional neural networks (CNNs), have led to a massive breakthrough in the range of computer vision. Also, the large-scale annotated dataset is the essential key to a successful training…

Segmentation and classification of large numbers of instances, such as cell nuclei, are crucial tasks in digital pathology for accurate diagnosis. However, the availability of high-quality datasets for deep learning methods is often limited…

Multi-class cell segmentation in high-resolution Giga-pixel whole slide images (WSI) is critical for various clinical applications. Training such an AI model typically requires labor-intensive pixel-wise manual annotation from experienced…

In the last decade, researchers working in the domain of computer vision and Artificial Intelligence (AI) have beefed up their efforts to come up with the automated framework that not only detects but also identifies stage of breast cancer.…

Supervised deep learning methods for segmentation require large amounts of labelled training data, without which they are prone to overfitting, not generalizing well to unseen images. In practice, obtaining a large number of annotations…

Computational pathology methods have the potential to improve access to precision medicine, as well as the reproducibility and accuracy of pathological diagnoses. Particularly the analysis of whole-slide-images (WSIs) of…

The past decade has witnessed a substantial increase in the number of startups and companies offering AI-based solutions for clinical decision support in medical institutions. However, the critical nature of medical decision-making raises…

Deep learning models often achieve expert-level accuracy in medical image classification but suffer from a critical flaw: semantic incoherence. These high-confidence mistakes that are semantically incoherent (e.g., classifying a malignant…

Breast cancer classification remains a challenging task due to inter-class ambiguity and intra-class variability. Existing deep learning-based methods try to confront this challenge by utilizing complex nonlinear projections. However, these…

Public imaging datasets are critical for the development and evaluation of automated tools in cancer imaging. Unfortunately, many do not include annotations or image-derived features, complicating their downstream analysis. Artificial…

Given multi-type point maps from different place-types (e.g., tumor regions), our objective is to develop a classifier trained on the source place-type to accurately distinguish between two classes of the target place-type based on their…

Skin cancer is one of the most common cancers worldwide and early detection is critical for effective treatment. However, current AI diagnostic tools are often trained on datasets dominated by lighter skin tones, leading to reduced accuracy…

Supervised deep learning models often achieve excellent performance within their training distribution but struggle to generalize beyond it. In cancer histopathology, for example, a convolutional neural network (CNN) may classify cancer…

Supervised learning-based segmentation methods typically require a large number of annotated training data to generalize well at test time. In medical applications, curating such datasets is not a favourable option because acquiring a large…

Breast cancer remains a critical global health challenge, necessitating early and accurate detection for effective treatment. This paper introduces a methodology that combines automated image augmentation selection (RandAugment) with search…

Treatment selection in breast cancer is guided by molecular subtypes and clinical characteristics. However, current tools including genomic assays lack the accuracy required for optimal clinical decision-making. We developed a novel…

Breast cancer detection through mammography interpretation remains difficult because of the minimal nature of abnormalities that experts need to identify alongside the variable interpretations between readers. The potential of CNNs for…

Computer-aided detection systems based on deep learning have shown great potential in breast cancer detection. However, the lack of domain generalization of artificial neural networks is an important obstacle to their deployment in changing…

High-resolution mapping of cells and tissue structures provides a foundation for developing interpretable machine-learning models for computational pathology. Deep learning algorithms can provide accurate mappings given large numbers of…

Convolutional Neural Network (CNN)-based accurate prediction typically requires large-scale annotated training data. In Medical Imaging, however, both obtaining medical data and annotating them by expert physicians are challenging; to…