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We develop estimation for potentially high-dimensional additive structural equation models. A key component of our approach is to decouple order search among the variables from feature or edge selection in a directed acyclic graph encoding…

Methodology · Statistics 2014-12-02 Peter Bühlmann , Jonas Peters , Jan Ernest

We investigate the identifiability of nonlinear Canonical Correlation Analysis (CCA) in a multi-view setup, where each view is generated by an unknown nonlinear map applied to a linear mixture of shared latents and view-private noise.…

Machine Learning · Computer Science 2026-03-02 Zhiwei Han , Stefan Matthes , Hao Shen

Although many studies collect biomedical time series signals from multiple subjects, there is a dearth of models and methods for assessing the association between frequency domain properties of time series and other study outcomes. This…

Applications · Statistics 2015-03-13 Robert T. Krafty , Martica Hall

Regularized generalized canonical correlation analysis (RGCCA) is a generalization of regularized canonical correlation analysis to three or more sets of variables, which is a component-based approach aiming to study the relationships…

Statistics Theory · Mathematics 2025-03-21 Kuo-Yue Li , Qi-Ye Zhang , Yong-Han Sun

Since the introduction of the lasso in regression, various sparse methods have been developed in an unsupervised context like sparse principal component analysis (s-PCA), sparse canonical correlation analysis (s-CCA) and sparse singular…

Methodology · Statistics 2020-12-09 Ruiping Liu , Ndeye Niang , Gilbert Saporta , Huiwen Wang

Drug discovery is the process of identifying compounds which have potentially meaningful biological activity. A major challenge that arises is that the number of compounds to search over can be quite large, sometimes numbering in the…

Applications · Statistics 2012-02-16 Daniel Samarov , J. S. Marron , Yufeng Liu , Christopher Grulke , Alexander Tropsha

Correspondence analysis (CA) is a multivariate statistical tool used to visualize and interpret data dependencies. CA has found applications in fields ranging from epidemiology to social sciences. However, current methods used to perform CA…

Machine Learning · Statistics 2019-02-22 Hsiang Hsu , Salman Salamatian , Flavio P. Calmon

In using multiple regression methods for prediction, one often considers the linear combination of explanatory variables as an index. Seeking a single such index when here are multiple responses is rather more complicated. One classical…

Methodology · Statistics 2020-11-19 Stephen Portnoy , Joseph Haimberg

We address the problem of predicting a target ordinal variable based on observable features consisting of functional profiles. This problem is crucial, especially in decision-making driven by sensor systems, when the goal is to assess an…

Modern biomedical studies often collect multi-view data, that is, multiple types of data measured on the same set of objects. A popular model in high-dimensional multi-view data analysis is to decompose each view's data matrix into a…

Machine Learning · Statistics 2022-09-19 Hai Shu , Zhe Qu , Hongtu Zhu

Canonical Variate Analysis (CVA) is a multivariate statistical technique and a direct application of Linear Discriminant Analysis (LDA) that aims to find linear combinations of variables that best differentiate between groups in a dataset.…

Computation · Statistics 2025-09-23 Raeesa Ganey , Sugnet Lubbe

We build on the interpretation of the Economic Complexity method as Correspondence Analysis (CA), and propose that the Canonical form of CA (CCA), which originated in the ecology literature, can be used to calculate multi-dimensional…

General Economics · Economics 2024-09-04 Önder Nomaler , Bart Verspagen

We propose using canonical correlation analysis (CCA) to generate features from sequences of medical billing codes. Applying this novel use of CCA to a database of medical billing codes for patients with diverticulitis, we first demonstrate…

Machine Learning · Statistics 2017-01-09 Corinne L. Jones , Sham M. Kakade , Lucas W. Thornblade , David R. Flum , Abraham D. Flaxman

Cross-modality retrieval encompasses retrieval tasks where the fetched items are of a different type than the search query, e.g., retrieving pictures relevant to a given text query. The state-of-the-art approach to cross-modality retrieval…

Information Retrieval · Computer Science 2018-04-17 Matthias Dorfer , Jan Schlüter , Andreu Vall , Filip Korzeniowski , Gerhard Widmer

Generalized correlation analysis (GCA) is concerned with uncovering linear relationships across multiple datasets. It generalizes canonical correlation analysis that is designed for two datasets. We study sparse GCA when there are…

Machine Learning · Statistics 2023-02-07 Sheng Gao , Zongming Ma

Reduced-rank linear discriminant analysis (RRLDA) is a foundational method of dimension reduction for classification that has been useful in a wide range of applications. The goal is to identify an optimal subspace to project the…

Computation · Statistics 2026-02-12 Jocelyn T. Chi

Having a large number of covariates can have a negative impact on the quality of causal effect estimation since confounding adjustment becomes unreliable when the number of covariates is large relative to the samples available. Propensity…

Methodology · Statistics 2020-09-15 Debo Cheng , Jiuyong Li , Lin Liu , Jixue Liu

Cortical pyramidal neurons receive inputs from multiple distinct neural populations and integrate these inputs in separate dendritic compartments. We explore the possibility that cortical microcircuits implement Canonical Correlation…

Neurons and Cognition · Quantitative Biology 2021-03-29 David Lipshutz , Yanis Bahroun , Siavash Golkar , Anirvan M. Sengupta , Dmitri B. Chklovskii

Recently proposed automatic pathological speech detection approaches rely on spectrogram input representations or wav2vec2 embeddings. These representations may contain pathology irrelevant uncorrelated information, such as changing…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-27 Yacouba Kaloga , Shakeel A. Sheikh , Ina Kodrasi

Comparing the functional behavior of neural network models, whether it is a single network over time or two (or more networks) during or post-training, is an essential step in understanding what they are learning (and what they are not),…

Computer Vision and Pattern Recognition · Computer Science 2022-11-10 Xingjian Zhen , Zihang Meng , Rudrasis Chakraborty , Vikas Singh