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Related papers: UniIF: Unified Molecule Inverse Folding

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Fundamental understanding of interatomic forces in molecules must emerge from quantum mechanics, yet widely used empirical force fields rely on simplified mechanistic approximations that often fail to capture the complexity of many-body…

Multi-modality image fusion (MMIF) combines complementary information from different image modalities to provide a comprehensive and objective interpretation of scenes. However, existing fusion methods cannot resist different weather…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Xilai Li , Wuyang Liu , Xiaosong Li , Fuqiang Zhou , Huafeng Li , Feiping Nie

This paper proposes an easy-to-use method for one-class classification: Repeated Element-wise Folding (REF). The algorithm consists of repeatedly standardizing and applying an element-wise folding operation on the one-class training data.…

Machine Learning · Computer Science 2025-06-19 Jenni Raitoharju

Predicting molecular impact on cellular function is a core challenge in therapeutic design. Phenomic experiments, designed to capture cellular morphology, utilize microscopy based techniques and demonstrate a high throughput solution for…

Quantitative Methods · Quantitative Biology 2024-09-16 Philip Fradkin , Puria Azadi , Karush Suri , Frederik Wenkel , Ali Bashashati , Maciej Sypetkowski , Dominique Beaini

Artificial intelligence for scientific discovery has recently generated significant interest within the machine learning and scientific communities, particularly in the domains of chemistry, biology, and material discovery. For these…

With the recent advances in machine learning for quantum chemistry, it is now possible to predict the chemical properties of compounds and to generate novel molecules. Existing generative models mostly use a string- or graph-based…

Biomolecules · Quantitative Biology 2020-10-14 Vitali Nesterov , Mario Wieser , Volker Roth

Multimodal learning has gained much success in recent years. However, current multimodal fusion methods adopt the attention mechanism of Transformers to implicitly learn the underlying correlation of multimodal features. As a result, the…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Thanh-Dat Truong , Christophe Bobda , Nitin Agarwal , Khoa Luu

Tokenizer is a crucial component for both visual understanding and generation. To advance toward the ultimate goal of universal modeling, recent research has focused on developing a unified tokenizer. However, existing tokenizers face a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Zhengrong Yue , Haiyu Zhang , Xiangyu Zeng , Boyu Chen , Chenting Wang , Shaobin Zhuang , Lu Dong , Yi Wang , Limin Wang , Yali Wang

Universal machine-learned interatomic potentials (U-MLIPs) have demonstrated broad applicability across diverse atomistic systems but often require fine-tuning to achieve task-specific accuracy. While the number of available U-MLIPs and…

Computational Physics · Physics 2025-08-25 Xiaoqing Liu , Kehan Zeng , Zedong Luo , Yangshuai Wang , Teng Zhao , Zhenli Xu

We propose UniT, a Unified Transformer model to simultaneously learn the most prominent tasks across different domains, ranging from object detection to natural language understanding and multimodal reasoning. Based on the transformer…

Computer Vision and Pattern Recognition · Computer Science 2021-08-19 Ronghang Hu , Amanpreet Singh

In contrast to supervised backpropagation-based feature learning in deep neural networks (DNNs), an unsupervised feedforward feature (UFF) learning scheme for joint classification and segmentation of 3D point clouds is proposed in this…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Min Zhang , Pranav Kadam , Shan Liu , C. -C. Jay Kuo

Accurate modelling of electrostatic interactions and charge transfer is fundamental to computational chemistry, yet most machine learning interatomic potentials (MLIPs) rely on local atomic descriptors that cannot capture long-range…

Machine-learning models of atomic-scale interactions achieve the accuracy of the quantum mechanical calculations on which they are trained, but at a dramatically lower computational cost. Their predictions can be made trustworthy by…

We introduce a new optical tool - a "two-dimensional optical centrifuge", capable of aligning molecules in extreme rotational states. Unlike the conventional centrifuge, which confines the molecules in the plane of their rotation, its…

Chemical Physics · Physics 2016-05-18 A. A. Milner , A. Korobenko , V. Milner

Several algorithms for RNA inverse folding have been used to design synthetic riboswitches, ribozymes and thermoswitches, whose activity has been experimentally validated. The RNAiFold software is unique among approaches for inverse folding…

Biomolecules · Quantitative Biology 2015-05-29 Juan Antonio Garcia-Martin , Ivan Dotu , Peter Clote

Materials discovery is decisive for tackling urgent challenges related to energy, the environment, health care and many others. In chemistry, conventional methodologies for innovation usually rely on expensive and incremental strategies to…

Machine Learning · Computer Science 2020-06-09 Daniel Schwalbe-Koda , Rafael Gómez-Bombarelli

Visual-language models have advanced the development of universal models, yet their application in medical imaging remains constrained by specific functional requirements and the limited data. Current general-purpose models are typically…

Computer Vision and Pattern Recognition · Computer Science 2024-10-08 Kaini Wang , Ling Yang , Siping Zhou , Guangquan Zhou , Wentao Zhang , Bin Cui , Shuo Li

Link prediction aims to identify potential missing triples in knowledge graphs. To get better results, some recent studies have introduced multimodal information to link prediction. However, these methods utilize multimodal information…

Artificial Intelligence · Computer Science 2023-03-21 Xinhang Li , Xiangyu Zhao , Jiaxing Xu , Yong Zhang , Chunxiao Xing

A scattering model is developed for ultracold molecular collisions, which allows inelastic processes, chemical reactions, and complex formation to be treated in a unified way. All these scattering processes and various combinations of them…

Atomic Physics · Physics 2020-09-23 James F. E. Croft , John L. Bohn , Goulven Quéméner

Following rapid advancements in text and image generation, research has increasingly shifted towards 3D generation. Unlike the well-established pixel-based representation in images, 3D representations remain diverse and fragmented,…

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