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Large language models (LLMs) are increasingly adopted in clinical decision support, yet aligning them with the multifaceted reasoning pathways of real-world medicine remains a major challenge. Using more than 8,000 infertility treatment…

Machine Learning · Computer Science 2025-11-25 Dou Liu , Ying Long , Sophia Zuoqiu , Kaipeng Xie , Runze Yang , Di Liu , Kang Li , Yiting Lin , Hanyi Liu , Rong Yin , Tian Tang

A safe and trustworthy use of Large Language Models (LLMs) requires an accurate expression of confidence in their answers. We propose a novel Reinforcement Learning approach that allows to directly fine-tune LLMs to express calibrated…

Computation and Language · Computer Science 2026-03-03 David Bani-Harouni , Chantal Pellegrini , Paul Stangel , Ege Özsoy , Kamilia Zaripova , Nassir Navab , Matthias Keicher

Pre-trained vision-language models (VLMs) exhibit strong zero-shot generalization but remain vulnerable to adversarial perturbations. Existing classification-guided adversarial fine-tuning methods often disrupt pre-trained cross-modal…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Yubo Cui , Xianchao Guan , Zijun Xiong , Zheng Zhang

Supervised fine-tuning (SFT) has emerged as one of the most effective ways to improve the performance of large language models (LLMs) in downstream tasks. However, SFT can have difficulty generalizing when the underlying data distribution…

Computation and Language · Computer Science 2025-12-15 Mrinal Rawat , Arkajyoti Chakraborty , Neha Gupta , Roberto Pieraccini

Large language models (LLMs) have been proposed as alternatives to human experts for estimating unknown quantities with associated uncertainty, a process known as Bayesian elicitation. We test this by asking eleven LLMs to estimate…

Artificial Intelligence · Computer Science 2026-04-03 Luka Hobor , Mario Brcic , Mihael Kovac , Kristijan Poje

Large Language Models (LLMs) exhibit impressive capabilities but also present risks such as biased content generation and privacy issues. One of the current alignment techniques includes principle-driven integration, but it faces challenges…

Computation and Language · Computer Science 2025-05-30 Yi Luo , Zhenghao Lin , Yuhao Zhang , Jiashuo Sun , Chen Lin , Chengjin Xu , Xiangdong Su , Yelong Shen , Jian Guo , Yeyun Gong

As Large Language Models (LLMs) continue to progress toward more advanced forms of intelligence, Reinforcement Learning from Human Feedback (RLHF) is increasingly seen as a key pathway toward achieving Artificial General Intelligence (AGI).…

Machine Learning · Computer Science 2024-10-17 Yuzi Yan , Xingzhou Lou , Jialian Li , Yiping Zhang , Jian Xie , Chao Yu , Yu Wang , Dong Yan , Yuan Shen

Advancements in Natural Language Processing (NLP), have led to the emergence of Large Language Models (LLMs) such as GPT, Llama, Claude, and Gemini, which excel across a range of tasks but require extensive fine-tuning to align their…

Computation and Language · Computer Science 2025-04-01 Angela Lopez-Cardona , Carlos Segura , Alexandros Karatzoglou , Sergi Abadal , Ioannis Arapakis

Reinforcement Learning from Human Feedback (RLHF) is increasingly used to align large language models (LLMs) with human preferences. However, the effectiveness of RLHF in addressing underlying biases remains unclear. This study investigates…

Computation and Language · Computer Science 2025-03-13 Logan Barnhart , Reza Akbarian Bafghi , Stephen Becker , Maziar Raissi

Learning to infer Bayesian posterior from a few-shot dataset is an important step towards robust meta-learning due to the model uncertainty inherent in the problem. In this paper, we propose a novel Bayesian model-agnostic meta-learning…

Machine Learning · Computer Science 2018-11-20 Taesup Kim , Jaesik Yoon , Ousmane Dia , Sungwoong Kim , Yoshua Bengio , Sungjin Ahn

Large language models (LLMs) are now rapidly advancing and surpassing human abilities on many natural language tasks. However, aligning these super-human LLMs with human knowledge remains challenging because the supervision signals from…

Computation and Language · Computer Science 2024-06-28 Yue Guo , Yi Yang

Pre-trained language models (PLMs) may fail in giving reliable estimates of their predictive uncertainty. We take a close look into this problem, aiming to answer two questions: (1) Do PLMs learn to become calibrated in the training…

Computation and Language · Computer Science 2023-05-09 Yangyi Chen , Lifan Yuan , Ganqu Cui , Zhiyuan Liu , Heng Ji

Large Language Models (LLM) alignment aims to prevent models from producing content that misaligns with human expectations, which can lead to ethical and legal concerns. In the last few years, Reinforcement Learning from Human Feedback…

Computation and Language · Computer Science 2024-10-10 Biao Liu , Ning Xu , Xin Geng

We propose an algorithm for meta-learning that is model-agnostic, in the sense that it is compatible with any model trained with gradient descent and applicable to a variety of different learning problems, including classification,…

Machine Learning · Computer Science 2017-07-19 Chelsea Finn , Pieter Abbeel , Sergey Levine

Driven by recent advances in artificial intelligence (AI), a growing literature has demonstrated the potential for using large language models (LLMs) as scalable surrogates to generate human-like responses in many business applications. Two…

Machine Learning · Computer Science 2025-12-30 Lei Wang , Zikun Ye , Jinglong Zhao

Large language models (LLMs) have demonstrated remarkable performance across various real-world tasks. However, they often struggle to fully comprehend and effectively utilize their input contexts, resulting in responses that are unfaithful…

Computation and Language · Computer Science 2024-09-18 Qingru Zhang , Xiaodong Yu , Chandan Singh , Xiaodong Liu , Liyuan Liu , Jianfeng Gao , Tuo Zhao , Dan Roth , Hao Cheng

Alignment of Large Language Models (LLMs) typically relies on Reinforcement Learning from Human Feedback (RLHF) with gradient-based optimizers such as Proximal Policy Optimization (PPO) or Group Relative Policy Optimization (GRPO). While…

Although large language models (LLMs) have demonstrated their effectiveness in a wide range of applications, they have also been observed to perpetuate unwanted biases present in the training data, potentially leading to harm for…

Computation and Language · Computer Science 2026-03-09 Schrasing Tong , Eliott Zemour , Jessica Lu , Rawisara Lohanimit , Lalana Kagal

Black-box tuning is an emerging paradigm for adapting large language models (LLMs) to better achieve desired behaviors, particularly when direct access to model parameters is unavailable. Current strategies, however, often present a dilemma…

Artificial Intelligence · Computer Science 2025-12-17 Zhikang Xie , Weilin Wan , Peizhu Gong , Weizhong Zhang , Cheng Jin

Safety alignment is a key requirement for building reliable Artificial General Intelligence. Despite significant advances in safety alignment, we observe that minor latent shifts can still trigger unsafe responses in aligned models. We…

Machine Learning · Computer Science 2025-06-23 Tianle Gu , Kexin Huang , Zongqi Wang , Yixu Wang , Jie Li , Yuanqi Yao , Yang Yao , Yujiu Yang , Yan Teng , Yingchun Wang